Protein Alignment AstC-R2 and cckbra

DIOPT Version :10

• Sequence 1: NP_001303398.1
• Gene: AstC-R2 / 40019
• FlyBaseID: FBgn0036789
• Length: 593
• Species: Drosophila melanogaster
• Sequence 2: NP_001108186.2
• Gene: cckbra / 100137117
• ZFINID: ZDB-GENE-060503-482
• Length: 444
• Species: Danio rerio
• Alignment Length: 439
• Identity: 107/439 - (24%)
• Similarity: 196/439 - (44%)
• Gaps: 130/439 - (29%)

  Fly    87 SVESESYPSINGT-QNETMVTSVRPHLDHRNRPTQQNGSHYLEYDDDGPDCSYSYNFILKLITMI 150
            |||      :|.| .|.:::...:|     .||.:.:.                       :.:|
Zfish    31 SVE------VNATCSNASIIQKFKP-----TRPKEMDS-----------------------VRII 61

  Fly   151 LYALVCIIGLFGNTLVIYVVMRFSKMQTVTNIYILNLAIADECFLI-GIPFLLYTMQVGNWPFGN 214
            ||:||.::.:|||.|:|.|::...:|:||||.::|:||::|....| .|||.|....:.::.||.
Zfish    62 LYSLVFLLSVFGNLLIIVVLIVNKRMRTVTNSFLLSLAVSDLMMAIFCIPFNLIPSLLEDFIFGA 126

  Fly   215 YMCK--AYM--VSTSITSFTSSIFLLIMSADRYIAVCHPISSPRYRTPFVSKLVSAFAWMTSVLL 275
            .|||  ||.  :|.||::|:    |:.::.:||.|:|:|:.|..::|...:..|.|..|:.||.:
Zfish   127 AMCKTVAYFMGISVSISTFS----LVAIAIERYSAICNPLKSRAWQTRSHAYKVIAATWVLSVAI 187

  Fly   276 MLPVILFASTVQ-SSNGNVS---CNIEWPDTQNSHTDSTFILYSLVLGFATPLTFILVFYCLVIR 336
            |:|..:|:..|. :...|::   |.:|||.:|   .:.|:.:..|.:.|..|...:::.|.|:.|
Zfish   188 MVPYPVFSILVPFNKTNNITAHMCRLEWPISQ---VEQTWYVLLLSILFFIPGVVMIIAYGLISR 249

  Fly   337 KLH---------------------------------------------------TVGP------- 343
            :|:                                                   |.||
Zfish   250 ELYRGIQFELEQKKDTSGVKNGLNGGLSSCHDESDGCYIQVSKKPPAMELSTLTTSGPVKTDRPR 314

  Fly   344 KHKSKEKKRSHRKVTKLVLTVISAYIFCWLP-----HW-----ISQVALISSAPQRCASRLELAV 398
            .:.|:.|..:.::|.::::.:::.:..||:|     .|     ||....:|.||   .|.::|
Zfish   315 SNTSEAKLIAKKRVIRMLIIIVAMFFVCWMPLYSANTWKAFDQISAQRALSGAP---ISFIQL-- 374

  Fly   399 FLACGCLSYSNSAMNPILYAFLSDNFKKSFMKACTCAARKDVNAQLQLE 447
                  |||:::.:|||:|.|::..|:|:.:....|..|...|.:.:.|
Zfish   375 ------LSYTSACVNPIIYCFMNTRFRKALLATFGCCRRPCHNRRKRKE 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstC-R2	NP_001303398.1	7tmA_AstC_insect	146..428	CDD:320222	94/358 (26%)
		TM helix 1	147..173	CDD:320222	11/25 (44%)
		TM helix 2	180..206	CDD:320222	11/26 (42%)
		TM helix 3	217..247	CDD:320222	12/33 (36%)
		TM helix 4	259..281	CDD:320222	7/21 (33%)
		TM helix 5	308..337	CDD:320222	6/28 (21%)
		TM helix 6	352..382	CDD:320222	7/39 (18%)
		TM helix 7	396..421	CDD:320222	9/24 (38%)
cckbra	NP_001108186.2	7tmA_CCK-BR	57..398	CDD:320645	94/381 (25%)
		TM helix 1	58..84	CDD:320645	11/25 (44%)
		TM helix 2	91..117	CDD:320645	11/25 (44%)
		TM helix 3	129..159	CDD:320645	12/33 (36%)
		TM helix 4	172..193	CDD:320645	7/20 (35%)
		TM helix 5	221..250	CDD:320645	6/28 (21%)
		TM helix 6	323..353	CDD:320645	4/29 (14%)
		TM helix 7	366..391	CDD:320645	12/35 (34%)