DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AstC-R2 and cmklr2

DIOPT Version :9

Sequence 1:	NP_001303398.1	Gene:	AstC-R2 / 40019	FlyBaseID:	FBgn0036789	Length:	593	Species:	Drosophila melanogaster
Sequence 2:	XP_001343514.2	Gene:	cmklr2 / 100004124	ZFINID:	ZDB-GENE-091204-457	Length:	356	Species:	Danio rerio

Alignment Length:	321	Identity:	89/321 - (27%)
Similarity:	153/321 - (47%)	Gaps:	21/321 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   121 QNGSHYLE---YDDDGPDCSYSYNFILKLITMILYALVCIIGLFGNTLVIYVVMRFSKMQTVTNI 182
            :|.:.|.:   |..|.....|:......:|::|:|:|...:|:.||..||:|. .|...:::.::
Zfish    10 ENDTVYFDETGYVVDSRSGGYTQREAFHIISVIIYSLAFTLGIIGNGTVIWVT-GFKIKRSINSV 73

  Fly   183 YILNLAIADECFLIGIPFLL-YTMQVGNWPFGNYMCKAYMVSTSITSFTSSIFLLIMSADRYIAV 246
            ::.||||||..|::.:||.: |.::..:|.||..|||......::..:.|.:||.::|.|||::.
Zfish    74 WLQNLAIADFVFVLFLPFSIDYVLRDFHWLFGKTMCKLNSFVCTMNMYASMLFLTVLSLDRYVSF 138

  Fly   247 CHPISSPRYRTPFVSKLVSAFAWMTSVLLMLPVILFASTVQSSNGNVSCNIEWPDTQNSHTDST- 310
            .|...|.:||....|..:.|..|:.|.:...|.::|...: ..||.:.|...:.| ::.|....
Zfish   139 VHFSWSQKYRNVRRSWWLCALIWIISCIFSCPALVFRDVI-LYNGKIVCFNHFHD-EDRHVMKMR 201

  Fly   311 ---FILYSLVLGFATPLTFILVFYCLVIRKLHTVGPKHKSKEKKRSHRKVTKLVLTVISAYIFCW 372
               .:.:..::||..|...|.|...|:..|:      .:|...:.|  ..:::|..||.|:..||
Zfish   202 HIGIVSFRTIVGFILPFATITVSGVLLALKM------RQSNSVRLS--SFSRMVSAVILAFFVCW 258

  Fly   373 LP-HWISQVALISSAPQRCASRLELAVFLACGCLSYSNSAMNPILYAFLSDNFKKSFMKAC 432
            .| |..|.:.|.........|.|.:...||.. |::.||.:|||||..|:...:|....||
Zfish   259 APFHTFSIMELSVHHSTALNSVLTIGFPLATS-LAFFNSCVNPILYVLLTKKVRKLVKSAC 318

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AstC-R2	NP_001303398.1	7tm_4	156..>372	CDD:304433	58/220 (26%)
AstC-R2	NP_001303398.1	7tm_1	162..417	CDD:278431	73/260 (28%)
cmklr2	XP_001343514.2	7tm_1	54..303	CDD:278431	73/260 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24229
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X22
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.100