Protein Alignment AstC-R2 and cmklr2

DIOPT Version :10

• Sequence 1: NP_001303398.1
• Gene: AstC-R2 / 40019
• FlyBaseID: FBgn0036789
• Length: 593
• Species: Drosophila melanogaster
• Sequence 2: XP_001343514.2
• Gene: cmklr2 / 100004124
• ZFINID: ZDB-GENE-091204-457
• Length: 356
• Species: Danio rerio
• Alignment Length: 321
• Identity: 89/321 - (27%)
• Similarity: 153/321 - (47%)
• Gaps: 21/321 - (6%)

  Fly   121 QNGSHYLE---YDDDGPDCSYSYNFILKLITMILYALVCIIGLFGNTLVIYVVMRFSKMQTVTNI 182
            :|.:.|.:   |..|.....|:......:|::|:|:|...:|:.||..||:|. .|...:::.::
Zfish    10 ENDTVYFDETGYVVDSRSGGYTQREAFHIISVIIYSLAFTLGIIGNGTVIWVT-GFKIKRSINSV 73

  Fly   183 YILNLAIADECFLIGIPFLL-YTMQVGNWPFGNYMCKAYMVSTSITSFTSSIFLLIMSADRYIAV 246
            ::.||||||..|::.:||.: |.::..:|.||..|||......::..:.|.:||.::|.|||::.
Zfish    74 WLQNLAIADFVFVLFLPFSIDYVLRDFHWLFGKTMCKLNSFVCTMNMYASMLFLTVLSLDRYVSF 138

  Fly   247 CHPISSPRYRTPFVSKLVSAFAWMTSVLLMLPVILFASTVQSSNGNVSCNIEWPDTQNSHTDST- 310
            .|...|.:||....|..:.|..|:.|.:...|.::|...: ..||.:.|...:.| ::.|....
Zfish   139 VHFSWSQKYRNVRRSWWLCALIWIISCIFSCPALVFRDVI-LYNGKIVCFNHFHD-EDRHVMKMR 201

  Fly   311 ---FILYSLVLGFATPLTFILVFYCLVIRKLHTVGPKHKSKEKKRSHRKVTKLVLTVISAYIFCW 372
               .:.:..::||..|...|.|...|:..|:      .:|...:.|  ..:::|..||.|:..||
Zfish   202 HIGIVSFRTIVGFILPFATITVSGVLLALKM------RQSNSVRLS--SFSRMVSAVILAFFVCW 258

  Fly   373 LP-HWISQVALISSAPQRCASRLELAVFLACGCLSYSNSAMNPILYAFLSDNFKKSFMKAC 432
            .| |..|.:.|.........|.|.:...||.. |::.||.:|||||..|:...:|....||
Zfish   259 APFHTFSIMELSVHHSTALNSVLTIGFPLATS-LAFFNSCVNPILYVLLTKKVRKLVKSAC 318

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstC-R2	NP_001303398.1	7tmA_AstC_insect	146..428	CDD:320222	82/287 (29%)
		TM helix 1	147..173	CDD:320222	10/25 (40%)
		TM helix 2	180..206	CDD:320222	10/26 (38%)
		TM helix 3	217..247	CDD:320222	9/29 (31%)
		TM helix 4	259..281	CDD:320222	5/21 (24%)
		TM helix 5	308..337	CDD:320222	6/32 (19%)
		TM helix 6	352..382	CDD:320222	10/30 (33%)
		TM helix 7	396..421	CDD:320222	10/24 (42%)
cmklr2	XP_001343514.2	7tm_GPCRs	38..314	CDD:475119	82/287 (29%)
		TM helix 1	40..64	CDD:410628	9/24 (38%)
		TM helix 2	72..93	CDD:410628	9/20 (45%)
		TM helix 3	110..132	CDD:410628	4/21 (19%)
		TM helix 4	155..171	CDD:410628	3/15 (20%)
		TM helix 5	203..226	CDD:410628	5/22 (23%)
		TM helix 6	244..266	CDD:410628	8/21 (38%)
		TM helix 7	282..307	CDD:410628	10/25 (40%)