DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5103 and AT3G60750

DIOPT Version :9

Sequence 1:	NP_649036.1	Gene:	CG5103 / 40012	FlyBaseID:	FBgn0036784	Length:	623	Species:	Drosophila melanogaster
Sequence 2:	NP_567103.1	Gene:	AT3G60750 / 825246	AraportID:	AT3G60750	Length:	741	Species:	Arabidopsis thaliana

Alignment Length:	725	Identity:	194/725 - (26%)
Similarity:	288/725 - (39%)	Gaps:	178/725 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 DSKVVQNLKDVAQKLRIHSITSTQAAKSGH---PTSCASLAEIMTVLFFQQMRLNLKHPRDPSSD 68
            ||.:|.  |.| ..:|..:|.:.:.|||||   |..||.:|.|   |:.:.||.|.|:|...:.|
plant    77 DSSIVD--KSV-NSIRFLAIDAVEKAKSGHPGLPMGCAPMAHI---LYDEVMRYNPKNPYWFNRD 135

  Fly    69 RLVLSKGHAAPILYAVWAEAGLFPV--EELRNLRKVDSDLEGHP----TPRLSFVDVSTGSLGQG 127
            |.|||.||...:|||:...||...|  |:|:..|:..|...|||    ||.   ::|:||.||||
plant   136 RFVLSAGHGCMLLYALLHLAGYDSVQEEDLKQFRQWGSKTPGHPENFETPG---IEVTTGPLGQG 197

  Fly   128 ISVAAGMAYVGKHL---------DKADYRTYVIVGDGEATEGAVWESLHFAGHYCLDNLCVIFDM 183
            |:.|.|:|...|||         :..|:.||.|:|||...||...|:...|||:.|..|...:|.
plant   198 IANAVGLALAEKHLAARFNKPDAEVVDHYTYAILGDGCQMEGISNEACSLAGHWGLGKLIAFYDD 262

  Fly   184 NKIFCSDIGTEM---EVYRERLDAFGFNAL-VLNGH-DIDELAKAFINAASTKGKPTALLARTTK 243
            |.| ..|..||:   |...:|.:|.|::.: |.||: ..||:..|...|.:...|||.:...||.
plant   263 NHI-SIDGDTEIAFTENVDQRFEALGWHVIWVKNGNTGYDEIRAAIKEAKTVTDKPTLIKVTTTI 326

  Fly   244 GKDFLGIEGIEEMHAQPLGKRAESAIKHLQMKIANPNVRLTPKKVGK------CGHAPE------ 296
            |...........:|...||::...|.::      |......|.:|..      ..|.||
plant   327 GYGSPNKANSYSVHGAALGEKEVEATRN------NLGWPYEPFQVPDDVKSHWSRHTPEGATLES 385

  Fly   297 -----------------VHINNIML--------CSPPNY---RLGDS--------------VAPR 319
                             ..:.:|:.        .:.|.|   ..||:              |.|.
plant   386 DWSAKFAAYEKKYPEEASELKSIITGELPAGWEKALPTYTPESPGDATRNLSQQCLNALAKVVPG 450

  Fly   320 LAYGTALAKIAADNPRVIALDGDTKNSTYADKMRNAFPERFIECFTAQQNL-VGV---AVGATCR 380
            ...|:  |.:|:.|..::...||.:.:|         ||        ::|| .||   .:||.|.
plant   451 FLGGS--ADLASSNMTLLKAFGDFQKAT---------PE--------ERNLRFGVREHGMGAICN 496

  Fly   381 ------RRTVAFVSTYATFFTRAFDQIRMGAISHTNVNFAGSHCGCSIGEDGPSQMGLEDMAMFR 439
                  ...:.:.:|:..|.......:|:.|:|...|.:..:|....:|||||:...:|.:|.||
plant   497 GIALHSPGLIPYCATFFVFTDYMRGAMRISALSEAGVIYVMTHDSIGLGEDGPTHQPIEHIASFR 561

  Fly   440 SIPGSTVFYPTDAVSTERAVELAANTKGVCYIRTT-------YPSTTVIYNNDEVFAVGLGKVVR 497
            ::|.:.:|.|.|...|..|.::|...:....|...       .|.|::     |....| |..:.
plant   562 AMPNTLMFRPADGNETAGAYKIAVTKRKTPSILALSRQKLPHLPGTSI-----EGVEKG-GYTIS 620

  Fly   498 QKPS---DEVLLIGAGVTLYECLAAAERLEEDCITARVI------------DPF--TVKPLDVGL 545
            ...|   .:|:|||.|..|.....|||.|.:|..|.||:            |.:  :|.|.||..
plant   621 DDSSGNKPDVILIGTGSELEIAAQAAEVLRKDGKTVRVVSFVCWELFDEQSDEYKESVLPSDVSA 685

  Fly   546 ---IVKHGKLCRGRIVVVEDHYQQGGLGEAVLSALADYRNFVVKHLYITTVPRSGPPAVLLDMFG 607
               |........|:||        ||.|               |.:.|.:...|.|..:|...||
plant   686 RVSIEAASTFGWGKIV--------GGKG---------------KSIGINSFGASAPAPLLYKEFG 727

  Fly   608 VSSRNIYKAS 617
            ::...:..|:
plant   728 ITVEAVVDAA 737

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5103	NP_649036.1	PRK05899	12..621	CDD:235639	191/720 (27%)
		TPP_TK	19..263	CDD:238970	94/266 (35%)
		TPP_PYR_DXS_TK_like	321..474	CDD:132916	40/162 (25%)
		Transketolase_C	493..613	CDD:280875	35/139 (25%)
AT3G60750	NP_567103.1	PLN02790	88..740	CDD:215424	189/711 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	118	1.000	Domainoid score	I1928
eggNOG	1	0.900	-	-		E1_COG0021
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	176	1.000	Inparanoid score	I1482
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D354970at2759
OrthoFinder	1	1.000	-	-		FOG0001032
OrthoInspector	1	1.000	-	-		mtm1210
orthoMCL	1	0.900	-	-		OOG6_100329
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	11	10.730