DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5103 and AT2G45290

DIOPT Version :9

Sequence 1:	NP_649036.1	Gene:	CG5103 / 40012	FlyBaseID:	FBgn0036784	Length:	623	Species:	Drosophila melanogaster
Sequence 2:	NP_001324258.1	Gene:	AT2G45290 / 819137	AraportID:	AT2G45290	Length:	741	Species:	Arabidopsis thaliana

Alignment Length:	724	Identity:	199/724 - (27%)
Similarity:	296/724 - (40%)	Gaps:	168/724 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 DSKVVQNLKDVAQKLRIHSITSTQAAKSGH---PTSCASLAEIMTVLFFQQMRLNLKHPRDPSSD 68
            ||.:|.  |.| ..:|..:|.:.:.|||||   |..||.::.|   |:.:.|:.|.|:|...:.|
plant    77 DSSLVD--KSV-NTIRFLAIDAVEKAKSGHPGLPMGCAPMSHI---LYDEVMKYNPKNPYWFNRD 135

  Fly    69 RLVLSKGHAAPILYAVWAEAGLFPV--EELRNLRKVDSDLEGHP----TPRLSFVDVSTGSLGQG 127
            |.|||.||...:.||:...||...|  |:|::.|:..|...|||    ||.   |:.:||.||||
plant   136 RFVLSAGHGCMLQYALLHLAGYDSVREEDLKSFRQWGSKTPGHPENFETPG---VEATTGPLGQG 197

  Fly   128 ISVAAGMAYVGKHL---------DKADYRTYVIVGDGEATEGAVWESLHFAGHYCLDNLCVIFDM 183
            |:.|.|:|...|||         :..|:.||.|:|||...||...|....|||:.|..|...:|.
plant   198 IANAVGLALAEKHLAARFNKPDNEIVDHYTYSILGDGCQMEGISNEVCSLAGHWGLGKLIAFYDD 262

  Fly   184 NKIFCSDIGTEM---EVYRERLDAFGFNAL-VLNGHD-IDELAKAFINAASTKGKPTALLARTTK 243
            |.| ..|..|::   |...:|.:|.|::.: |.||:: .||:..|...|.:...|||.:...||.
plant   263 NHI-SIDGDTDIAFTESVDKRFEALGWHVIWVKNGNNGYDEIRAAIREAKAVTDKPTLIKVTTTI 326

  Fly   244 GKDFLGIEGIEEMHAQPLGKRAESAIK----------HLQMKIANPNVRLTPKKVGKCGHAPEVH 298
            |...........:|...||::...|.:          |:...:.:...|.||:     |.|.|..
plant   327 GYGSPNKANSYSVHGAALGEKEVEATRNNLGWPYEPFHVPEDVKSHWSRHTPE-----GAALEAD 386

  Fly   299 INNIMLCSPPNY-----RLGDSVAPRLAYG--TALAKIAADNPRVIALDGD-TKNSTY------- 348
            .|.........|     .|...::..|..|  .||.....|:|      || |:|.:.
plant   387 WNAKFAAYEKKYPEEAAELKSIISGELPVGWEKALPTYTPDSP------GDATRNLSQQCLNALA 445

  Fly   349 ----------AD------KMRNAFPERFIECFTAQQNL-VGV---AVGATCR---RRTVAFVSTY 390
                      ||      .|..|| ..|.:....::|| .||   .:||.|.   ..:..|:...
plant   446 KAVPGFLGGSADLASSNMTMLKAF-GNFQKATPEERNLRFGVREHGMGAICNGIALHSPGFIPYC 509

  Fly   391 ATFFT-----RAFDQIRMGAISHTNVNFAGSHCGCSIGEDGPSQMGLEDMAMFRSIPGSTVFYPT 450
            ||||.     ||  .:|:.|:|...|.:..:|....:|||||:...:|.::.||::|...:|.|.
plant   510 ATFFVFTDYMRA--AMRISALSEAGVIYVMTHDSIGLGEDGPTHQPIEHLSSFRAMPNIMMFRPA 572

  Fly   451 DAVSTERAVELAA---NTKGVCYIR----TTYPSTTV---------IYNNDEVFAVGLGKVVRQK 499
            |...|..|.::|.   .|..|..:.    ...|.|::         |.:|.          ...|
plant   573 DGNETAGAYKIAVTKRKTPSVLALSRQKLPQLPGTSIESVEKGGYTISDNS----------TGNK 627

  Fly   500 PSDEVLLIGAGVTLYECLAAAERLEEDCITARVI------------DPF--TVKPLDVG--LIVK 548
            |  :|:|||.|..|.....|||:|.|...:.||:            |.:  :|.|.||.  :.::
plant   628 P--DVILIGTGSELEIAAQAAEKLREQGKSVRVVSFVCWELFDEQSDAYKESVLPSDVSARVSIE 690

  Fly   549 HGKLCR-GRIVVVEDHYQQGGLGEAVLSALADYRNFVVKHLYITTVPRSGPPAVLLDMFGVSSRN 612
            .|.... |:||        ||.|               |.:.|.|...|.|...|...||::...
plant   691 AGSTFGWGKIV--------GGKG---------------KSIGIDTFGASAPAGKLYKEFGITIEA 732

  Fly   613 IYKASLAIM 621
            :.:|:.:::
plant   733 MVEAAKSLI 741

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5103	NP_649036.1	PRK05899	12..621	CDD:235639	196/717 (27%)
		TPP_TK	19..263	CDD:238970	90/266 (34%)
		TPP_PYR_DXS_TK_like	321..474	CDD:132916	51/197 (26%)
		Transketolase_C	493..613	CDD:280875	35/136 (26%)
AT2G45290	NP_001324258.1	PLN02790	88..741	CDD:215424	194/708 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	118	1.000	Domainoid score	I1928
eggNOG	1	0.900	-	-		E1_COG0021
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	176	1.000	Inparanoid score	I1482
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D354970at2759
OrthoFinder	1	1.000	-	-		FOG0001032
OrthoInspector	1	1.000	-	-		mtm1210
orthoMCL	1	0.900	-	-		OOG6_100329
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.730