DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp312a1 and CYP704B1

DIOPT Version :9

Sequence 1:	NP_001262008.1	Gene:	Cyp312a1 / 40005	FlyBaseID:	FBgn0036778	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_177109.3	Gene:	CYP704B1 / 843283	AraportID:	AT1G69500	Length:	524	Species:	Arabidopsis thaliana

Alignment Length:	534	Identity:	128/534 - (23%)
Similarity:	224/534 - (41%)	Gaps:	108/534 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 HKW-----PAPPALPFIGHLHILAKLVGPHPLRRATEMINEHLHDHR---AKLWMGTKLYLVDCN 88
            |:|     ..|...|.:|     |.:.......|..:.:.|:|::.|   ..:...|..|:.|
plant    18 HRWGQRNKSGPKTWPLVG-----AAIEQLTNFDRMHDWLVEYLYNSRTVVVPMPFTTYTYIAD-- 75

  Fly    89 PKDIQALCSAQQLLQKTNDYRVFENW-------------LCEGLFTSGFEKWSHRRKIVMPAFNY 140
            |.::       :.:.|||    |.|:             |.:|:|.|..|.|..:||.....|..
plant    76 PINV-------EYVLKTN----FSNYPKGETYHSYMEVLLGDGIFNSDGELWRKQRKTASFEFAS 129

  Fly   141 TMIKQF-VAVFEKQSRILLTNVAKFAESGDQIDFLQLISCFTLDTICETALGVSVGSQSS--AKS 202
            ..::.| ..||::.|..|.|.:::.:....|:|..:|:...|||:||:...||.:|:.:.  .::
plant   130 KNLRDFSTVVFKEYSLKLFTILSQASFKEQQVDMQELLMRMTLDSICKVGFGVEIGTLAPELPEN 194

  Fly   203 EYLDAVKSILVIIDKRLKNIFYRNSFIFKRTSHYKREQEL---IKTLHGFTEGIIQKRIDEINQ- 263
            .:..|..:..:|:..|..:..::    .|:..:...|..|   ||.::.||..:|::|..|:.:
plant   195 HFAKAFDTANIIVTLRFIDPLWK----MKKFLNIGSEALLGKSIKVVNDFTYSVIRRRKAELLEA 255

  Fly   264 ---DAENRNYQSSDAELDGVKRTLCFLDTLLLSKGPDGKPLTVKDIREEVDTIIFGGFDLTATTL 325
               ...|.|..::..:.|.:.|   |::   :|..||.|. |.|.:|:.|...:..|.|.|||||
plant   256 QISPTNNNNNNNNKVKHDILSR---FIE---ISDDPDSKE-TEKSLRDIVLNFVIAGRDTTATTL 313

  Fly   326 NFFMY---------------------------NMTLH---PEHQQRCREEVWSVCGKDKSEPISI 360
            .:.:|                           |.:||   .|......|:|....|.     ::.
plant   314 TWAIYMIMMNENVAEKLYSELQELEKESAEATNTSLHQYDTEDFNSFNEKVTEFAGL-----LNY 373

  Fly   361 EQVRQLEFLEACIKETLRMYPSGPLTARKATANCTINDFFIPKGSD------VIISPIYMGRCK- 418
            :.:.:|.:|.|.|.||||:||:.|...:.     .:.|..:|.|:.      |...|..|||.:
plant   374 DSLGKLHYLHAVITETLRLYPAVPQDPKG-----VLEDDMLPNGTKVKAGGMVTYVPYSMGRMEY 433

  Fly   419 DFFPDPMVFKPDRW-AIGAEPKIEATTFIPFMAGARSCMGQRYAMVMLKMVLAHLLRNFLFEPLG 482
            ::..|..:|||:|| ..|.........|..|.||.|.|:|:..|.:.:||.:|.|.|.:.|..:.
plant   434 NWGSDAALFKPERWLKDGVFQNASPFKFTAFQAGPRICLGKDSAYLQMKMAMAILCRFYKFHLVP 498

  Fly   483 ERQVKLKLNFVITL 496
            ...||.::..::::
plant   499 NHPVKYRMMTILSM 512

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp312a1	NP_001262008.1	p450	35..505	CDD:278495	126/526 (24%)
CYP704B1	NP_177109.3	PLN03195	1..524	CDD:215627	128/534 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	1	0.900	-	-		OOG6_100859
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.810