DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp312a1 and CYP96A8

DIOPT Version :9

Sequence 1:	NP_001262008.1	Gene:	Cyp312a1 / 40005	FlyBaseID:	FBgn0036778	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_175193.1	Gene:	CYP96A8 / 841171	AraportID:	AT1G47620	Length:	520	Species:	Arabidopsis thaliana

Alignment Length:	532	Identity:	118/532 - (22%)
Similarity:	215/532 - (40%)	Gaps:	85/532 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 GLLLLALSLYLL------YVFERQSRIDRLTHKWPAPPALPFIGHLHILAKLVGPHPLRRATEMI 65
            |.|...:|.|.|      |:..::: :......||....||     .:|.:      |:|..:..
plant    12 GFLCFLISFYFLVKKPFSYLLIKKT-LQSYPWNWPVLGMLP-----GVLLR------LQRIYDCS 64

  Fly    66 NEHLHDHRAKL-----WMGTKLYLVDCNPKDIQALCSA--QQLLQKTNDYRVFENWLCEGLFTSG 123
            .|.|.:.....     |......|...:|.:|..:.|:  ...::....:.:||.: .:|:..:.
plant    65 VEVLENSNMTFQFKGPWFVGMDVLATVDPANIHHIMSSNFSNYIKGPIFHEIFEAF-GDGIINTD 128

  Fly   124 FEKWSHRRKIVMPAFNYTMIKQFVAVFEK----QSRILLTNVAKFAESGDQIDFLQLISCFTLDT 184
            .|.|...|......||:...:.|.|...|    ...:.|.|  .||.....:|...:...|..|.
plant   129 AELWRDWRNASQLIFNHQRYQNFSASTTKTKVNDGLVPLFN--HFANEEIVVDLEDVFQRFMYDI 191

  Fly   185 ICETALG-----VSVGSQSSAKSEYLDAVKSILVIIDKRLKNIFYRNSFIFKRTSHYKREQELIK 244
            ......|     :|:.......|:.||.|...:|     .::|..|..:..::......|::::|
plant   192 TFIFITGTDPRSLSIEMPEVEFSKALDDVGDAIV-----HRHITPRFVWKLQKWIGIGTEKKMLK 251

  Fly   245 ---TLHGFTEGIIQKRIDEI-------NQDAENRNYQSSDAELDGVKRTLCFLDTLLLSKGPDGK 299
               |.....|.||..:.:|:       |.:.|..:..:|..:||..|..:.             |
plant   252 AHATFDRVCEKIIAAKREELGSQGITYNSNGEREDLLTSFIKLDATKYEVL-------------K 303

  Fly   300 PLTVKDIREEVDTIIFGGFDLTATTLNFFMYNMTLHPEHQQRCREEVWSVCGKDKSEPISIEQVR 364
            |...|.:|:.....:..|.|.||:||.:|.:|::.:|....:..:|:.:...:..|:......:.
plant   304 PSHDKFLRDFTIGFMAAGRDSTASTLTWFFWNLSKNPNVLTKILQEINTNLPRTGSDQDMSSYLN 368

  Fly   365 QLEFLEACIKETLRMYPSGPLTARKATANCTINDFFIPKGSDV-----IISPIY-MGRCKDFF-P 422
            :|.:|...:.|::|:||..|. .||:    .|.:..:|.|..|     |:..|| |||.|..: .
plant   369 KLVYLHGALSESMRLYPPIPF-QRKS----PIKEDVLPSGHKVKSNINIMIFIYAMGRMKTIWGE 428

  Fly   423 DPMVFKPDRW-----AIGAEPKIEATTFIPFMAGARSCMGQRYAMVMLKMVLAHLLRNFLFEPLG 482
            |.|.|||:||     .:..||..:   |:.|.||.|:|:|:..||.::|.|:..:|:|:..:.:.
plant   429 DAMEFKPERWISETGGVRHEPSYK---FLSFNAGPRTCLGKNLAMNLMKTVIVEILQNYEIKIVS 490

  Fly   483 ERQVKLKLNFVI 494
            .::::.|...::
plant   491 GQKIEPKPGLIL 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp312a1	NP_001262008.1	p450	35..505	CDD:278495	111/498 (22%)
CYP96A8	NP_175193.1	p450	1..515	CDD:386267	118/532 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.000