DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp312a1 and CYP94D1

DIOPT Version :9

Sequence 1:	NP_001262008.1	Gene:	Cyp312a1 / 40005	FlyBaseID:	FBgn0036778	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_174713.1	Gene:	CYP94D1 / 840356	AraportID:	AT1G34540	Length:	498	Species:	Arabidopsis thaliana

Alignment Length:	529	Identity:	122/529 - (23%)
Similarity:	233/529 - (44%)	Gaps:	91/529 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LLLLALSLYLLYVFERQSRIDRLTHKWPAPPALPFIGHLHILAKLVGPHPLRRATEMINEHLHDH 72
            ||...:|::.:: |.::|..:.....:|                :||..|     .::|..   |
plant     9 LLCFPISIFFIF-FTKKSSSEFGFKSYP----------------IVGSFP-----GLVNNR---H 48

  Fly    73 RAKLWM-----------------GTKLYLVDCNPKDIQALCSAQ-QLLQKTNDY-RVFENWLCEG 118
            |...|.                 |.:..::..||.:::.:...: :...|...: .|.|::|..|
plant    49 RFLDWTVETLSRCPTQTAIFRRPGKQQLIMTANPSNVEYMLKTKFESFPKGQQFTSVLEDFLGHG 113

  Fly   119 LFTSGFEKWSHRRKIVMPAFNYTMIKQFV---AVFEKQSRILLTNVAKFAESGDQIDFLQLISCF 180
            :|.|..:.|..:||.....|:...::.||   ...|..:| |:..:.:.|.:|..||...::..|
plant   114 IFNSDGDMWWKQRKTASYEFSTKSLRDFVMSNVTVEINTR-LVPVLVEAATTGKLIDLQDILERF 177

  Fly   181 TLDTICETALGVS---VGSQSSAKSEYLDAVKSILVIIDKRLKNIFYRNSFIFKRTSHYKRE--- 239
            ..|.||:.|..|.   :|...:....::.|.::...||.:|.::: ...::..|:..:...|
plant   178 AFDNICKLAFNVDCACLGHDGAVGVNFMRAFETAATIISQRFRSV-ASCAWRIKKKLNIGSERVL 241

  Fly   240 QELIKTLHGFTEGIIQKRIDEINQDAENRNYQSSDAELDGVKRTLCFLDTLLLSKGPDGKPLTVK 304
            :|.|.|:|.|.:.|::.|||:         .:|||.:.|.:.|        .:||.....|..::
plant   242 RESIATVHKFADEIVRNRIDQ---------GRSSDHKEDLLSR--------FISKEEMNSPEILR 289

  Fly   305 DIREEVDTIIFGGFDLTATTLNFFMYNMTLHPEHQQRCREEVWSV---CGKDKSEPISIEQVRQL 366
            ||   |.:.|..|.|.|::.|::|.:.:::|||.:.:..:|:.|:   .||...|....|.::.:
plant   290 DI---VISFILAGRDTTSSALSWFFWLLSMHPEVEDKILQELNSIRARTGKRIGEVYGFEHLKMM 351

  Fly   367 EFLEACIKETLRMYPSGPLTARKATANCTIND-FFIPKGSDVIISPIYMGRCKDFF-PDPMVFKP 429
            .:|.|.|.|:||:||..|:..:....:..:.| .|:.||..:..:...|||.:..: .|...|.|
plant   352 NYLHAAITESLRLYPPVPVDIKSCAEDNVLPDGTFVGKGWAITYNIFAMGRMESIWGKDCDRFDP 416

  Fly   430 DRWA-------IGAEPKIEATTFIPFMAGARSCMGQRYAMVMLKMVLAHLLRNFLFEPLGERQVK 487
            :||.       .|.:|    :.|..|.||.|.|:|:..|.:.:|.::|.:|..|:.|..|:.:.:
plant   417 ERWIDETNGCFRGEDP----SKFPAFHAGPRMCVGKDMAYIQMKSIVAAVLERFVVEVPGKERPE 477

  Fly   488 LKLNFVITL 496
            :.|:..:.:
plant   478 ILLSMTLRI 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp312a1	NP_001262008.1	p450	35..505	CDD:278495	117/502 (23%)
CYP94D1	NP_174713.1	CYP86A	64..490	CDD:410687	109/449 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	1	0.900	-	-		OOG6_100859
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.810