DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp312a1 and CYP97A3

DIOPT Version :9

Sequence 1:	NP_001262008.1	Gene:	Cyp312a1 / 40005	FlyBaseID:	FBgn0036778	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_564384.1	Gene:	CYP97A3 / 840067	AraportID:	AT1G31800	Length:	595	Species:	Arabidopsis thaliana

Alignment Length:	454	Identity:	111/454 - (24%)
Similarity:	212/454 - (46%)	Gaps:	41/454 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 KLWMGTKLYLVDCNP-------KDIQALCSAQQLLQKTNDYRVFENWLCEGLFTSGFEKWSHRRK 132
            :|..|.|.:|:..:|       || .|...::.:|.:..|:     .:.:||..:..|.|..||:
plant   144 RLTFGPKSFLIVSDPSIAKHILKD-NAKAYSKGILAEILDF-----VMGKGLIPADGEIWRRRRR 202

  Fly   133 IVMPAFNYTMIKQFVAVFEKQSRILLTNVAKFAESGDQIDFLQLISCFTLDTICETALGVSVGSQ 197
            .::||.:...:...:::|.:.|..|...:...|..|::::...|.|..|||.|.:........|.
plant   203 AIVPALHQKYVAAMISLFGEASDRLCQKLDAAALKGEEVEMESLFSRLTLDIIGKAVFNYDFDSL 267

  Fly   198 SSAKSEYLDAVKSIL-VIIDKRLKNIFYRNSFIFKRTSHYKRE-QELIKTLHGFTEGIIQ--KRI 258
            :: .:..::||.::| ...|:.:..|...:..|:|..|..:|: ...:|.::...:.:|.  ||:
plant   268 TN-DTGVIEAVYTVLREAEDRSVSPIPVWDIPIWKDISPRQRKVATSLKLINDTLDDLIATCKRM 331

  Fly   259 DEINQDAENRNYQSSDAELDGVKRTLCFLDTLLLSKGPDGKPLTVKDIREEVDTIIFGGFDLTAT 323
            .|..:...:..|.:        :|....|..||.|    |..::.|.:|:::.|::..|.:.:|.
plant   332 VEEEELQFHEEYMN--------ERDPSILHFLLAS----GDDVSSKQLRDDLMTMLIAGHETSAA 384

  Fly   324 TLNFFMYNMTLHPEHQQRCREEVWSVCGKDKSEPISIEQVRQLEFLEACIKETLRMYPSGPLTAR 388
            .|.:..|.:|..|....:.:|||.||.| |:..  :|:.:::|::....:.|:||:||..|:..|
plant   385 VLTWTFYLLTTEPSVVAKLQEEVDSVIG-DRFP--TIQDMKKLKYTTRVMNESLRLYPQPPVLIR 446

  Fly   389 KATANCTINDFFIPKGSDVIISPIYMGRCKDFFPDPMVFKPDRWAI-GAEPK--IEATTFIPFMA 450
            ::..|..:.::.|.:|.|:.||...:.|....:.|...|.|:||.: |..|.  .:..:::||..
plant   447 RSIDNDILGEYPIKRGEDIFISVWNLHRSPLHWDDAEKFNPERWPLDGPNPNETNQNFSYLPFGG 511

  Fly   451 GARSCMGQRYAMVMLKMVLAHLLRNFLFEPLGERQVKLKLNFVITLHTVE----PYLCRAKNLD 510
            |.|.|:|..:|.....:.:|.|:|.|.|: :......:|:....|:||.|    ....|.|.||
plant   512 GPRKCIGDMFASFENVVAIAMLIRRFNFQ-IAPGAPPVKMTTGATIHTTEGLKLTVTKRTKPLD 574

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp312a1	NP_001262008.1	p450	35..505	CDD:278495	107/447 (24%)
CYP97A3	NP_564384.1	PLN02738	1..595	CDD:215393	111/454 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53736
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24291
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	7.020