DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp312a1 and CYP715A1

DIOPT Version :9

Sequence 1:	NP_001262008.1	Gene:	Cyp312a1 / 40005	FlyBaseID:	FBgn0036778	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_200053.2	Gene:	CYP715A1 / 835316	AraportID:	AT5G52400	Length:	519	Species:	Arabidopsis thaliana

Alignment Length:	513	Identity:	120/513 - (23%)
Similarity:	221/513 - (43%)	Gaps:	70/513 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MFWLGFGLLLLALSLYLLYVFER--------QSRIDRLTHKWPAPPALPFIGHLHILAKLVGPHP 57
            ::::.|.:.::.:.|..|.:|.|        |.::.......|| |:.|| |:|:.:.||.....
plant     9 VWYIFFKVFVVVICLMFLKLFLRCWIWPVRAQKKLRGNGFVGPA-PSFPF-GNLNDMKKLKMASV 71

  Fly    58 L---RRATEMINEHLHD----HRAK----------LWMGTKLYLVDCNPKDIQALCSAQQLLQKT 105
            :   .:::.:||..:|.    |.|:          .|:|.:.::...:|:.:..:  ::.:|.|:
plant    72 VVDNSKSSTIINHDIHSIALPHFARWQQEYGKVFVYWLGIEPFVYVADPEFLSVM--SKGVLGKS 134

  Fly   106 -NDYRVFENWLCEGLFTSGF-----EKWSHRRKIVMPAFNYTMIKQFVAVFEKQSRILLTNVAKF 164
             ....||:... |.:|.:|.     :.|:..|.|:.|||....:|....:..:....:|......
plant   135 WGKPNVFKKDR-EPMFGTGLVMVEGDDWTRHRHIITPAFAPLNLKVMTNMMVESVSNMLDRWGIQ 198

  Fly   165 AESGD-QIDFLQLISCFTLDTICETALGVSVGSQSSAKSEYLDAVKSILVIIDKRLKNIFYRNSF 228
            ..||: :.|....|.....:.|.:|:.||: |...:...:.|.||:..| ....|...:.:.|..
plant   199 INSGNPEFDMESEIIGTAGEIIAKTSFGVT-GENGTQVLKNLRAVQFAL-FNSNRYVGVPFSNIL 261

  Fly   229 IFKRTSHYKREQELIKTLHGFTEGIIQKRIDEINQDAENRNYQSSDAELDGVKRTLCFLDTLLLS 293
            .:|:|   .:.:.|...:.|.....|.||             :.|.||.|.....|.   .:||.
plant   262 SYKQT---VKAKGLGHEIDGLLLSFINKR-------------KISLAEGDDQGHDLL---GMLLK 307

  Fly   294 KGPDGKPLTVKDIREEVDTIIFGGFDLTATTLNFFMYNMTLHPEHQQRCREEVWSVCGKDKSEPI 358
            ....|. .|.|::.:|..|..|.|.:.||..|.:....:.:|||.|...|||:..|.|..|.|..
plant   308 ADQKGN-FTAKELVDECKTFFFAGHETTALALTWTFMLLAIHPEWQDTIREEIREVIGDSKIEYN 371

  Fly   359 SIEQVRQLEFLEACIKETLRMYPSGPLTARKATANCTINDFFIPKGSDVIISPIYMGRCKDFFPD 423
            .:..::::.::   :.|.||:||..|...|:|..:..:|...||.|:::.|..:.|....:.:.|
plant   372 KLAGLKKMSWV---MNEVLRLYPPAPNAQRQARNDIEVNGRVIPNGTNIWIDVVAMHHDVELWGD 433

  Fly   424 PM-VFKPDRW----AIGAEPKIEATTFIPFMAGARSCMGQRYAMVMLKMVLAHLLRNF 476
            .: .|||:|:    ..|.:.|:   .::||..|.|.|:|:....:..|:||:.:|..|
plant   434 DVNEFKPERFDGNLHGGCKNKM---GYMPFGFGGRMCIGRNLTTMEYKIVLSLVLSRF 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp312a1	NP_001262008.1	p450	35..505	CDD:278495	114/471 (24%)
CYP715A1	NP_200053.2	p450	16..519	CDD:299894	119/506 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.960