DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp312a1 and CYP714A2

DIOPT Version :9

Sequence 1:	NP_001262008.1	Gene:	Cyp312a1 / 40005	FlyBaseID:	FBgn0036778	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_197872.1	Gene:	CYP714A2 / 832559	AraportID:	AT5G24900	Length:	525	Species:	Arabidopsis thaliana

Alignment Length:	509	Identity:	118/509 - (23%)
Similarity:	217/509 - (42%)	Gaps:	86/509 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 PPALPFIGHLHILAKLVGPHPLRRATEMINEHLHDHRAKL------W-----------MGTKLYL 84
            ||...|.|::..:.::...........:|:   ||:.:.|      |           .|.|.:|
plant    50 PPPSIFNGNVSEMQRIQSEAKHCSGDNIIS---HDYSSSLFPHFDHWRKQYGRIYTYSTGLKQHL 111

  Fly    85 VDCNPKDIQALCSAQ--QLLQKTNDYRVFENWLCEGLFTSGFEKWSHRRKIVMPAFNYTMIKQFV 147
            ...:|:.::.|....  .|.:.|:..:.....|..|:.||....|:|:|:|:...|.:..||..|
plant   112 YINHPEMVKELSQTNTLNLGRITHITKRLNPILGNGIITSNGPHWAHQRRIIAYEFTHDKIKGMV 176

  Fly   148 AVFEKQSRILLTN----VAKFAESGDQIDFLQLISCFTLDTICETALGVSVGSQSSAKSEYLDAV 208
            .:..:.:..:|..    |.:..|.|..|...:.:...:.|.|.:...|   .|.|..|:.: ..:
plant   177 GLMVESAMPMLNKWEEMVKRGGEMGCDIRVDEDLKDVSADVIAKACFG---SSFSKGKAIF-SMI 237

  Fly   209 KSILVIIDKRLKNIFYRNSFIFKRTSHYKREQELIKTLHGFTEGII-QKRIDEINQDAENRNYQS 272
            :.:|..|.||        |.:|:              .:|||:.:. .|:..:::.||.....:|
plant   238 RDLLTAITKR--------SVLFR--------------FNGFTDMVFGSKKHGDVDIDALEMELES 280

  Fly   273 SDAELDGVKRTLCFLDT-------LLLS---KGPDG----KPLTVKDIREEVDTIIFGGFDLTAT 323
            |..|....:...| .||       |:|.   :..||    |....:.:.:...:|.|.|.|.||.
plant   281 SIWETVKEREIEC-KDTHKKDLMQLILEGAMRSCDGNLWDKSAYRRFVVDNCKSIYFAGHDSTAV 344

  Fly   324 TLNFFMYNMTLHPEHQQRCREEVWSVCGKDKSEPISIEQVRQLEFLEACIKETLRMYPSGPLTAR 388
            ::::.:..:.|:|..|.:.|:|:.|.|   |:.....|.:..|:.:...|:||:|:||..|:..|
plant   345 SVSWCLMLLALNPSWQVKIRDEILSSC---KNGIPDAESIPNLKTVTMVIQETMRLYPPAPIVGR 406

  Fly   389 KATANCTINDFFIPKGSDVIISPIYMGRCKD---FFPDPMVFKPDRWAIGAEPKIE-ATTFIPFM 449
            :|:.:..:.|..:|||  |.|..:.....:|   :.||...|||:|::.|.....: ..::|||.
plant   407 EASKDIRLGDLVVPKG--VCIWTLIPALHRDPEIWGPDANDFKPERFSEGISKACKYPQSYIPFG 469

  Fly   450 AGARSCMGQRYAMVMLKMVLAHLLRNFLF--EPLGERQVKLKLNFVITLHTVEP 501
            .|.|:|:|:.:.|:.:|::::.::..|.|  .|..:.....||       .|||
plant   470 LGPRTCVGKNFGMMEVKVLVSLIVSKFSFTLSPTYQHSPSHKL-------LVEP 516

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp312a1	NP_001262008.1	p450	35..505	CDD:278495	118/509 (23%)
CYP714A2	NP_197872.1	p450	37..524	CDD:299894	118/509 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.960