DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp312a1 and AT5G08250

DIOPT Version :9

Sequence 1:	NP_001262008.1	Gene:	Cyp312a1 / 40005	FlyBaseID:	FBgn0036778	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_001330676.1	Gene:	AT5G08250 / 830721	AraportID:	AT5G08250	Length:	550	Species:	Arabidopsis thaliana

Alignment Length:	555	Identity:	118/555 - (21%)
Similarity:	230/555 - (41%)	Gaps:	107/555 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LSLYL-LYVFERQSRIDRLTHKWPAPPALPFIGHLHILAKLVGPHPLRRATEMINEHLHDHRAK- 75
            |.|:: .:||.....:.:..|:  ..|..|.:|.|..|...|..:.....::::.......|.:
plant    40 LELFIAFFVFATIHSLRQKKHQ--GMPVWPLVGMLPSLISAVRSNIYEWLSDVLISQNGTFRFRG 102

  Fly    76 LWMGTKLYLVDCNPKDIQALCSAQQLLQKTNDY--RVFENWLCEGLFTSGFEKWSHRRKIVMPAF 138
            .|..|...:|.|:|::::.|...:..:.....|  ...::.|.:|:|.:....|..:||.....|
plant   103 PWFSTLNCVVTCDPRNVEHLLKTRFSIYPKGSYFRETMQDLLGDGIFNTDDGTWQRQRKAASVEF 167

  Fly   139 NYTMIKQFVAVFEKQSRILLTNVAKFAESGDQIDFLQLISCFTLDTICETALGVSVGSQSSAKSE 203
            :....:|..:  :....::...:....|:..:||...::...|.|.:|..|.||..|..|....|
plant   168 HSAKFRQLTS--QSLHELVHNRLLPVLETSGKIDLQDILLRLTFDNVCMIAFGVDPGCLSPKLPE 230

  Fly   204 ------YLDAVKSILVIIDKRLKNIFYRNSFIFK--RTSHYKREQELIKTLHG---FTEGIIQKR 257
                  :.||.::.:|        .|....|::|  |:.:...|::|.::::|   |.|.:|:.|
plant   231 IPFAKAFEDATEATVV--------RFVMPKFVWKLMRSLNLGTEKKLKESINGVDDFAEEVIRTR 287

  Fly   258 IDEINQDAENRNYQSSDAELDGVKRTLCFLDTLLLSKGPD------------GKPLTVKDIREEV 310
            ..|::.:.|                         ::|.||            |:..:.|.:|:..
plant   288 KKEMSLETE-------------------------IAKRPDLLTIFMGLRDENGQKFSDKFLRDIC 327

  Fly   311 DTIIFGGFDLTATTLNFFMYNMTLHPEHQQRCREEVWSVC---------GKDKS----EPI-SIE 361
            ...|..|.|.::..|::|.:.:..:||.:::.   :..:|         |..|.    ||: ..|
plant   328 VNFILAGRDTSSVALSWFFWLIEKNPEVEEKI---MMGICKILEQRVDHGDTKKNMEYEPVFRPE 389

  Fly   362 QVRQLEFLEACIKETLRMYPSGPLTARKATANCTINDFF-----IPKGSDVIISPIYMGRCKDFF 421
            :::::::|:|.:.||||:|||.|:..::...    :|.|     :.||..||.:...|||.:..:
plant   390 EIKKMDYLQAALSETLRLYPSVPVDHKEVLE----DDVFPDGTKLKKGEKVIYAIYAMGRMETIW 450

  Fly   422 -PDPMVFKPDRW-AIGAEPKIEATTFIPFMAGARSCMGQRYAMVMLKMVLAHLLRNF--LFEPLG 482
             .|...|||:|| ..|......|..|..|..|.|.|:|:.:|...::.|.|.::..:  ..:..|
plant   451 GKDCREFKPERWLRDGRYMSESAYKFTAFNGGPRLCLGKDFAYYQMRYVAAAIIYRYKVRVDDKG 515

  Fly   483 ERQVK------------LKLNFV-ITLHTVEPYLC 504
            ..:|:            ||:|.| .::..::.|.|
plant   516 GHKVEPKMALTMYMKHGLKVNMVKRSVSEIDHYYC 550

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp312a1	NP_001262008.1	p450	35..505	CDD:278495	113/532 (21%)
AT5G08250	NP_001330676.1	CYP86A	98..533	CDD:410687	101/476 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53736
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	1	0.900	-	-		OOG6_100859
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.820