DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp312a1 and CYP94D2

DIOPT Version :9

Sequence 1:	NP_001262008.1	Gene:	Cyp312a1 / 40005	FlyBaseID:	FBgn0036778	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_191222.1	Gene:	CYP94D2 / 824830	AraportID:	AT3G56630	Length:	499	Species:	Arabidopsis thaliana

Alignment Length:	519	Identity:	121/519 - (23%)
Similarity:	222/519 - (42%)	Gaps:	95/519 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LLALSLYLLYVFERQSRIDRLTHKWPAPPALPFIGHLHILAKLVGPHPLRRATEMINEHLHDHRA 74
            ||...:.:.::|..::.......|     :.|.:|.|               ..::|..   ||.
plant     9 LLCFPIVIFFIFFPKNSSSEFGFK-----SYPIVGSL---------------PGLVNNR---HRF 50

  Fly    75 KLWM-----------------GTKLYLVDCNPKDIQALCSAQ-QLLQKTNDY-RVFENWLCEGLF 120
            ..|.                 |...:::..||.:::.:...: :...|...: .:.|::|..|:|
plant    51 LDWTVETLSRCPTQTAIFRRPGKLQFVMTANPANVEYMLKTKFESFPKGERFISILEDFLGRGIF 115

  Fly   121 TSGFEKWSHRRKIVMPAFNYTMIKQFV---AVFEKQSRILLTNVAKFAESGDQIDFLQLISCFTL 182
            .|..|.|..:||.....|:...::.||   ...|..:| |:..:|:.|.:|..||...::..|..
plant   116 NSDGEMWWKQRKTASYEFSTKSLRDFVMSNVTVEINTR-LVPVLAEAATNGKLIDLQDILERFAF 179

  Fly   183 DTICETALGVS---VGSQSSAKSEYLDAVKSILVIIDKRLKNIFYRNSFIFKRTSHYKRE---QE 241
            |.||:.|..|.   :|...:|...::.|.::...||.:|.:::. ..|:..|:..:...|   :|
plant   180 DNICKLAFNVDSACLGDDGAAGVNFMQAFETAATIISQRFQSVI-SYSWKIKKKLNIGSERVLRE 243

  Fly   242 LIKTLHGFTEGIIQKRIDEINQDAENRNYQSSDAELDGVKRTLCFLDTLLLSKGPDGKPLTVKDI 306
            .|..:|.|.:.|::.||::         .:.||.:.|.:.|        .:||.....|..::||
plant   244 SIMIVHKFADEIVRNRIEQ---------GKVSDHKEDLLSR--------FISKEEMNSPEILRDI 291

  Fly   307 REEVDTIIFGGFDLTATTLNFFMYNMTLHPEHQQRCREEVWSV---CGKDKSEPISIEQVRQLEF 368
               |.:.|..|.|.|::.|::|.:.:::|||.:.:..:|:.|:   .||...|....|.::.:.:
plant   292 ---VISFILAGRDTTSSALSWFFWLLSMHPEVKDKILQELNSIRERTGKRIGEVYGFEDLKLMNY 353

  Fly   369 LEACIKETLRMYPSGPL-TARKATANCTINDFFIPKGSDVIISPIYMGRCKDFF-PDPMVFKPDR 431
            |.|.|.|:||:||..|: |...|..|...:..||.|...:..:...|||.:..: .|...|.|:|
plant   354 LHAAITESLRLYPPVPVDTMSCAEDNVLPDGTFIGKDWGISYNAYAMGRMESIWGKDCDRFDPER 418

  Fly   432 WAIGAEPKIEATT----------FIPFMAGARSCMGQRYAMVMLKMVLAHLLRNFLFEPLGERQ 485
            |       |:.|.          |..|.||.|.|:|:..|.:.:|.::|.:|..|:.|..|:::
plant   419 W-------IDETNGGFRGENPYKFPAFHAGPRMCLGKEMAYIQMKSIVAAVLERFVVEVPGKKE 475

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp312a1	NP_001262008.1	p450	35..505	CDD:278495	117/494 (24%)
CYP94D2	NP_191222.1	p450	52..499	CDD:299894	111/453 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	1	0.900	-	-		OOG6_100859
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.810