DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp312a1 and CYP72A10

DIOPT Version :9

Sequence 1:	NP_001262008.1	Gene:	Cyp312a1 / 40005	FlyBaseID:	FBgn0036778	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_188082.2	Gene:	CYP72A10 / 820692	AraportID:	AT3G14640	Length:	536	Species:	Arabidopsis thaliana

Alignment Length:	501	Identity:	129/501 - (25%)
Similarity:	204/501 - (40%)	Gaps:	87/501 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 PALPFIGHL----HILAKL--------------VGPHPLRRATEMINEHLHDHRAKLWMGTKLYL 84
            |..|.||.|    ::|.:.              |.|||.    :|:.  .|......|:|.|..:
plant    70 PYTPLIGDLKRNVNMLTEATSKPIKLTEDITPRVLPHPF----QMLK--THGRTFFTWLGPKPTI 128

  Fly    85 VDCNPKDIQALCSAQQLLQKTNDYRVFENWLCEGLFTSGF-----EKWSHRRKIVMPAFNYTMIK 144
            ...:|:.|      :::..|..||...:.:|...|..:|.     :||:..|:|:.|||:...||
plant   129 TIMDPELI------KEVFNKVYDYPKAQTFLLGRLIATGIINYDGDKWAKHRRIINPAFHIEKIK 187

  Fly   145 QFVAVFEKQSRILLTNVAKF----AESGDQIDFLQLISCFTLDTICETALGVSVGSQSSAKSEYL 205
            ..|..|.:....::...:|.    ..|..::|....:...|.|.|..||.|.|............
plant   188 NMVPAFHQSCSDVVGEWSKLVSDKGSSSCEVDVWPWLVSMTGDVISRTAFGSSYKEGQRIFELQA 252

  Fly   206 DAVKSILVIIDKRLKNIFYRNSFIFKRTSHYKREQELIKTLHGFTEGIIQKRI--DEINQDAENR 268
            :.|..||....|     .|...:.:..|...:|.:...:.:....:||:.||:  .|..:.|.|.
plant   253 ELVHLILQAFWK-----VYIPGYRYLPTKSNRRMKAAAREIQVILKGIVNKRLRAREAGKAAPND 312

  Fly   269 NYQSSDAELDGVKRTLCFLDTLLLSK--GPDGKPLTVKDIREEVDTIIFGGFDLTATTLNFFMYN 331
            :                .|..||.|.  ...|..::.:|:.||.....|.|.:.|:..|.:.|..
plant   313 D----------------LLGILLESNLGQAKGNGMSTEDVMEECKLFYFAGQETTSVLLVWAMVL 361

  Fly   332 MTLHPEHQQRCREEVWSVCGKDKSEPISIEQVRQLEFLEACIKETLRMYPSGPLT--ARKATANC 394
            ::.|.:.|.|.||||..|.| || || ..|.:.||:.:...:.|.||:||  |:|  .|......
plant   362 LSHHQDWQARAREEVKQVFG-DK-EP-DTECLSQLKVMTMILYEVLRLYP--PVTHLTRAIDKEM 421

  Fly   395 TINDFFIPKGSDVIISPIYMGRCKDFFPDPMV-------FKPDRWAIGAEPKIEA-TTFIPFMAG 451
            .:.|..:|.|..:.:..:.:.|      |||:       |||:|:..|.....:: .:|.||..|
plant   422 KLGDLTLPAGVHISLPIMLVQR------DPMLWGTDAAEFKPERFKDGLSKATKSQVSFFPFAWG 480

  Fly   452 ARSCMGQRYAMVMLKMVLAHLLRNFLFEPLGERQVKLKLNFVITLH 497
            .|.|:||.:||:..||.:|.:|:.|.|| |....|... ..|:|:|
plant   481 PRICIGQNFAMLEAKMAMALILQTFTFE-LSPSYVHAP-QTVVTIH 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp312a1	NP_001262008.1	p450	35..505	CDD:278495	129/501 (26%)
CYP72A10	NP_188082.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D825914at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.970