DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp312a1 and CYP704A2

DIOPT Version :9

Sequence 1:	NP_001262008.1	Gene:	Cyp312a1 / 40005	FlyBaseID:	FBgn0036778	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_182075.1	Gene:	CYP704A2 / 819159	AraportID:	AT2G45510	Length:	511	Species:	Arabidopsis thaliana

Alignment Length:	533	Identity:	122/533 - (22%)
Similarity:	227/533 - (42%)	Gaps:	97/533 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LLLALSLYLLY-VFERQSRIDRLTHKWPAPPALPFIGHLHILAKLVGPHPLRRATEMINEHLHDH 72
            ::|..::||:. :|..:||.|:   ::....|..|....|                  ::.|:|:
plant    17 IVLCFTIYLMIRIFTGKSRNDK---RYAPVHATVFDLLFH------------------SDELYDY 60

  Fly    73 RAKLWMGTKLY---------LVDCNPKDIQALCSAQQLLQKTNDYRVFENW-------------L 115
            ..::......|         ::..:|::::.:...:           |:|:             |
plant    61 ETEIAREKPTYRFLSPGQSEILTADPRNVEHILKTR-----------FDNYSKGHSSRENMADLL 114

  Fly   116 CEGLFTSGFEKWSHRRKIVMPAFNYTMIKQF-VAVFEKQSRILLTNVAKFAESGDQIDFLQLISC 179
            ..|:|....|||..:||:....|:..:::.| .:||.:.:..|:..|::||.||...|...|:..
plant   115 GHGIFAVDGEKWRQQRKLSSFEFSTRVLRDFSCSVFRRNASKLVGFVSEFALSGKAFDAQDLLMR 179

  Fly   180 FTLDTICETALGVS---VGSQSSAKSEYLDAVKSILVIIDKRLKNIFYRNSFIFKRTSHYKREQE 241
            .|||:|.:...||.   :...|....|:::|.....|....|..:..::..:.|...|..|.::.
plant   180 CTLDSIFKVGFGVELKCLDGFSKEGQEFMEAFDEGNVATSSRFIDPLWKLKWFFNIGSQSKLKKS 244

  Fly   242 LIKTLHGFTEGIIQKRIDEINQDAENRNYQSSDAELDGVKRTLCFLDTLLLSKGPDGKPLTVKDI 306
             |.|:..|...:|..:..|:.::      |::....|       .|...|:....|.:.:..|.:
plant   245 -IATIDKFVYSLITTKRKELAKE------QNTVVRED-------ILSRFLVESEKDPENMNDKYL 295

  Fly   307 REEVDTIIFGGFDLTATTLNFFMYNMTLHPEHQQRCREEVWSVC-GKDKS-------EPISIEQV 363
            |:.:...:..|.|.||..|::|:|.:..:|..|::..:|:..|. ..:|:       |.|:.|.:
plant   296 RDIILNFMIAGKDTTAALLSWFLYMLCKNPLVQEKIVQEIRDVTFSHEKTTDVNGFVESINEEAL 360

  Fly   364 RQLEFLEACIKETLRMYPSGPLTARKATANCTINDFFIP------KGSDVIISPIYMGRCKDFF- 421
            .::.:|.|.:.||||:||..|:..|     |..||..:|      ||.::......|||....:
plant   361 DEMHYLHAALSETLRLYPPVPVDMR-----CAENDDVLPDGHRVSKGDNIYYIAYAMGRMTYIWG 420

  Fly   422 PDPMVFKPDRWAIGA--EPKIEATTFIPFMAGARSCMGQRYAMVMLKMVLAHLLRNFLFEPLGER 484
            .|...|||:||....  :|: ....||.|.||.|.|:|:.:|...:|:|...||..|.|: :.:.
plant   421 QDAEEFKPERWLKDGLFQPE-SPFKFISFHAGPRICLGKDFAYRQMKIVSMALLHFFRFK-MADE 483

  Fly   485 QVKLKLNFVITLH 497
            ..|:....::|||
plant   484 NSKVYYKRMLTLH 496

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp312a1	NP_001262008.1	p450	35..505	CDD:278495	115/506 (23%)
CYP704A2	NP_182075.1	PLN03195	15..509	CDD:215627	122/533 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53736
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	1	0.900	-	-		OOG6_100859
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.820