Protein Alignment Cyp312a1 and cyp46a1.2

DIOPT Version :9

• Sequence 1: NP_001262008.1
• Gene: Cyp312a1 / 40005
• FlyBaseID: FBgn0036778
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_001072550.1
• Gene: cyp46a1.2 / 780005
• XenbaseID: XB-GENE-5802444
• Length: 503
• Species: Xenopus tropicalis
• Alignment Length: 550
• Identity: 139/550 - (25%)
• Similarity: 249/550 - (45%)
• Gaps: 103/550 - (18%)

  Fly     3 W--LGF-GLLLLALSL--------YLLYVFERQSRIDRLTHKWPAPPALPFI-GHLHILAKLVGP 55
            |  ||: .||||||.|        |:.|:..:...|       |.||...|| ||...|.|||..
 Frog     4 WAILGWAALLLLALILICFLLYCGYIHYIHMKYDHI-------PGPPRDSFIFGHSTALLKLVNE 61

  Fly    56 H---------------PLRRATEMINEHLHDHRAKLWMGTKLYLVDCNPKDIQALCSAQQLLQKT 105
            :               |:.|    || .||          |:.::..:|:.|:....:.:.| |.
 Frog    62 NLLMYDYFLDWVHKYGPVMR----IN-GLH----------KVAVLVASPEGIKEFLMSPKYL-KD 110

  Fly   106 NDYRVF-----ENWLCEGLFTS-GFEKWSHRRKIVMPAFNYTMIKQFVAVFEKQSRILLTNVAKF 164
            ..|..|     |..:.:||.|. .::.|..:|:|:.|||:.|.:...:..|.:::..|:..:::.
 Frog   111 EFYDFFGSLFGERLMGKGLLTDRDYDHWHKQRRIMDPAFSRTYLMGLMGPFNEKAEELMEKLSEN 175

  Fly   165 AESGDQIDFLQLISCFTLDTICETALGVSVGSQSSAKSEYLDAVKSILVIIDKRLKNIFYRNSFI 229
            ::...:::...:.|..|||.|.:...|:.:.|.:..::.:..|:..::      ..::..||..|
 Frog   176 SDRKCEVNMHDMFSKVTLDVIGKVGFGMELNSLNDDQTPFPRAISLVM------KGSVEIRNPMI 234

  Fly   230 ---FKRTSHYKREQELIKTLHGFTEGIIQKRIDEINQDAENRNYQSSDAELDGVKRTL------- 284
               ..:....::.||.|:.|....:..|::|..:| ||.|       :..:|.:.:.|
 Frog   235 KYSLAKRGLIRKVQESIRLLRQTGKECIERRQKQI-QDGE-------EIPVDILTQILRGTALEK 291

  Fly   285 -CFLDTLLLSKGPDGKPLTVKDIREEVDTIIFGGFDLTATTLNFFMYNMTLHPEHQQRCREEVWS 348
             |..:|||                :...|....|.:.||..|:|.:.::..:||..::.:.|:..
 Frog   292 DCDPETLL----------------DNFVTFFIAGQETTANQLSFAVMSLGRNPEILKKAQAEIDE 340

  Fly   349 VCGKDKSEPISIEQVRQLEFLEACIKETLRMYPSGPLTARKATANCTINDFFIPKGSDVIISPIY 413
            |.|..:.  |..|.:.:|.:|...:|||||:||:.|.|:|.......|::..||....::::...
 Frog   341 VIGSKRD--IEYEDLGKLSYLSQVLKETLRLYPTAPGTSRTLENEIVIDEVRIPGNVTLMLNSYV 403

  Fly   414 MGRCKDFFPDPMVFKPDRWAIGAEPKIEATTFIPFMAGARSCMGQRYAMVMLKMVLAHLLRNFLF 478
            |||.:.::.||::|.|||::..| || ...|:.||..|.|:|:||.::.:..|:|:|..|:.:.|
 Frog   404 MGRMEQYYKDPLMFNPDRFSPDA-PK-PYFTYFPFSLGPRNCIGQVFSQMEAKVVMAKFLQRYEF 466

  Fly   479 EPLGERQVKLKLNFVITLHTVEPYLCRAKN 508
            | |.|.| ..|:....||..::..:||.::
 Frog   467 E-LAEGQ-SFKILDTGTLRPLDGVICRLRS 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp312a1	NP_001262008.1	p450	35..505	CDD:278495	124/502 (25%)
cyp46a1.2	NP_001072550.1	p450	40..482	CDD:365848	122/493 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D825914at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010