Protein Alignment Cyp312a1 and cyp46a1.1

DIOPT Version :9

• Sequence 1: NP_001262008.1
• Gene: Cyp312a1 / 40005
• FlyBaseID: FBgn0036778
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_001027519.1
• Gene: cyp46a1.1 / 613111
• XenbaseID: XB-GENE-22069537
• Length: 507
• Species: Xenopus tropicalis
• Alignment Length: 556
• Identity: 149/556 - (26%)
• Similarity: 243/556 - (43%)
• Gaps: 117/556 - (21%)

  Fly     3 WLGFG---LLLLALSL--------YLLYVFERQSRIDRLTHKWPAPPALPFI-GHLHILAKLV-- 53
            |..||   ||||||:|        |:.|:..:...|       |.||...|| ||...:.:|:
 Frog     4 WALFGWASLLLLALTLICFLLFCGYIQYIHMKYDHI-------PGPPRDGFIFGHSPTILRLMKN 61

  Fly    54 ---------------GP----HPLRRATEMINEHLHDHRAKLWMGTKLYLVDCNPKDIQALCSAQ 99
                           ||    :.|.|...:|...         .|.|.:|:  :||
 Frog    62 NKVVYDQYLDWVQKYGPVVRINALHRVIVLITSP---------EGVKEFLM--SPK--------- 106

  Fly   100 QLLQKTNDY-RVFE----NWLCEGLFT-SGFEKWSHRRKIVMPAFNYTMIKQFVAVFEKQSRILL 158
              ..|.:.| ||..    .::.:||.| ...:.|..:|:|:.|||:.|.:...:..|.:::..|:
 Frog   107 --YSKNDIYDRVATLYGMRFMGKGLVTDKDHDHWYKQRRIMDPAFSRTYLMDLMGPFNEKAEELM 169

  Fly   159 TNVAKFAESGDQIDFLQLISCFTLDTICETALGVSVGSQSSAKSEYLDAVKSIL-VIIDKRLKNI 222
            ..:::.|:.....:...|.|..|||.|.:.|.|:.:.|.....:....|:..:: .|::.|...|
 Frog   170 ERLSEQADGKSDTEMHNLFSRVTLDVIAKVAFGMELNSLKDDLTPLPQAISLVMNGIVETRNPMI 234

  Fly   223 FY---RNSFIFKRTSHYKREQELIKTLHGFTEGIIQKRIDEINQDAENRNYQSSDAELDGVKRTL 284
            .|   :..||       ::.||.|:.|....:..|::|..:| ||.|       :..:|.:.:.|
 Frog   235 KYSLAKRGFI-------RKVQESIRLLRQTGKECIERRQKQI-QDGE-------EIPMDILTQIL 284

  Fly   285 CFLDTLLLSKG----PDGKPLTVKDIREEVDTIIFGGFDLTATTLNFFMYNMTLHPEHQQRCREE 345
                     ||    .|..|.|:.|   ...|....|.:.||..|:|.:..:..:||..|:.::|
 Frog   285 ---------KGAALEEDCDPETLLD---NFVTFFIAGQETTANQLSFAVMELGRNPEILQKAQKE 337

  Fly   346 VWSVCGKDKSEPISIEQVRQLEFLEACIKETLRMYPSGPLTARKATANCTINDFFIPKGSDVIIS 410
            :..|.|..:.  |..|.:.:|.:|...:|||||:||:.|.|:|.......|....||...:|:.:
 Frog   338 IDEVIGSRRF--IEHEDLSKLHYLSQVLKETLRLYPTAPGTSRGLKEEIVIEGVRIPPNVNVMFN 400

  Fly   411 PIYMGRCKDFFPDPMVFKPDRWAIGAEPKIEATTFIPFMAGARSCMGQRYAMVMLKMVLAHLLRN 475
            ...|||.:..:.||:.|.|||::.|| || ...|:.||..|.|||:||.::.:..|:|:|.||:.
 Frog   401 SYIMGRMEQNYTDPLTFNPDRFSPGA-PK-PYYTYFPFSLGPRSCIGQVFSQMEAKVVMAKLLQR 463

  Fly   476 FLFEPLGERQVKLKLNFVI----TLHTVEPYLCRAK 507
            :.|| |.|.|     :|.|    :|..::..:||.:
 Frog   464 YDFE-LAEGQ-----SFSIFDTGSLRPLDGVICRLR 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp312a1	NP_001262008.1	p450	35..505	CDD:278495	134/509 (26%)
cyp46a1.1	NP_001027519.1	p450	40..491	CDD:306555	134/509 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D825914at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010