Protein Alignment Cyp312a1 and cyp46a1.3

DIOPT Version :9

• Sequence 1: NP_001262008.1
• Gene: Cyp312a1 / 40005
• FlyBaseID: FBgn0036778
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_001027517.1
• Gene: cyp46a1.3 / 613109
• XenbaseID: XB-GENE-969052
• Length: 504
• Species: Xenopus tropicalis
• Alignment Length: 550
• Identity: 137/550 - (24%)
• Similarity: 252/550 - (45%)
• Gaps: 105/550 - (19%)

  Fly     3 WLGFG---LLLLALSL--------YLLYVFERQSRIDRLTHKWPAPPALP-FIGHLHILAKLVGP 55
            |...|   ||||||.|        |:.|:..:...|       |.||... |:||...:.:|:..
 Frog     4 WALIGWAALLLLALILICFLLFSGYIHYIHMKYDHI-------PGPPRDSFFLGHSPTMLRLMKN 61

  Fly    56 HPLRRATEMINEHLHDHRAKLWMG--------------TKLYLVDCNPKDIQALCSAQQLLQKTN 106
            :.|          ::||    ::|              .::.::..:|:.::.|..:.: ..|..
 Frog    62 NLL----------MYDH----FLGWVQKYGPVVRINGLHRVIILVVSPEAVKELLMSPK-YSKDK 111

  Fly   107 DYRVFEN-----WLCEGLFTS-GFEKWSHRRKIVMPAFNYTMIKQFVAVFEKQSRILLTNVAKFA 165
            .|.|..|     ::.:||.|. .::.|..:|:|:.|||:.|.:...:..|.:::..|:..:.:.|
 Frog   112 FYDVIANMFGVRFMGKGLVTDRDYDHWHKQRRIMDPAFSRTYLMGLMGPFNEKAEELMEKLMEKA 176

  Fly   166 ESGDQIDFLQLISCFTLDTICETALGVSVGSQSSAKSEYLDAVKSILV-IIDKRLKNIFY---RN 226
            :...:|....::|..|||.|.:.|.|:.:.|.:...:.:..|:..::. |::.|...:.|   :.
 Frog   177 DGKCEIKMHDMLSRLTLDVIGKVAFGMELNSLNDDLTPFPKAISLVMKGIVEMRNPMVRYSLAKR 241

  Fly   227 SFIFKRTSHYKREQELIKTLHGFTEGIIQKRIDEINQDAENRNYQSSDAELDGVKRTLCFLDTLL 291
            .||       ::.||.|:.|....:..|::|..:| ||.|       :..:|.:.:.|
 Frog   242 GFI-------RKVQESIRLLRQTGKECIERRQKQI-QDGE-------EIPVDILTQIL------- 284

  Fly   292 LSKGPDGKPLTVKDIREEVD---------TIIFGGFDLTATTLNFFMYNMTLHPEHQQRCREEVW 347
              ||        ..:.||.|         |....|.:.||..|:|.:..:..:||..::.:.|:.
 Frog   285 --KG--------AAMEEECDPEILLDNFVTFFIAGQETTANQLSFVVMELGRNPEILEKAQAEID 339

  Fly   348 SVCGKDKSEPISIEQVRQLEFLEACIKETLRMYPSGPLTARKATANCTINDFFIPKGSDVIISPI 412
            .|.|..:.  |..|.:.:|::|...:|||||:||:.|.|:|..|.:..|:...:|:...::::..
 Frog   340 EVIGSKRD--IEYEDLGKLQYLSQVLKETLRLYPTAPGTSRGLTEDMVIDGVKVPENVTIMLNSY 402

  Fly   413 YMGRCKDFFPDPMVFKPDRWAIGAEPKIEATTFIPFMAGARSCMGQRYAMVMLKMVLAHLLRNFL 477
            .|||.:.::.||:.|.|||::..| || ...::.||..|.|||:||.::.:..|:|:|.||:.:.
 Frog   403 IMGRMEQYYSDPLTFNPDRFSPDA-PK-PYYSYFPFSLGPRSCIGQVFSQMEAKVVMAKLLQRYE 465

  Fly   478 FEPLGERQVKLKLNFVITLHTVEPYLCRAK 507
            || |.|.| ..|:....||..::..:||.:
 Frog   466 FE-LAEGQ-SFKILDTGTLRPLDGVICRLR 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp312a1	NP_001262008.1	p450	35..505	CDD:278495	123/503 (24%)
cyp46a1.3	NP_001027517.1	p450	40..491	CDD:306555	123/503 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D825914at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920