Protein Alignment Cyp312a1 and cyp46a1.1

DIOPT Version :9

• Sequence 1: NP_001262008.1
• Gene: Cyp312a1 / 40005
• FlyBaseID: FBgn0036778
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_001018358.1
• Gene: cyp46a1.1 / 553543
• ZFINID: ZDB-GENE-050522-464
• Length: 501
• Species: Danio rerio
• Alignment Length: 533
• Identity: 140/533 - (26%)
• Similarity: 246/533 - (46%)
• Gaps: 66/533 - (12%)

  Fly     1 MFWLGFGLLLLALSLYL---LYVFERQSRIDRLTHKWPAPPALPF-IGHLHILAKLVGPHPLRRA 61
            :.::.|.||....:.:|   ||:.....:.|.:    |.||...| :||...|.|         |
Zfish     6 VLYIVFFLLAAVFTAFLGYCLYIHHLHQKYDHI----PGPPRDSFLLGHSSSLTK---------A 57

  Fly    62 TEMINEHLHD---HRAKLW-----MGTKLY---LVDCNPKDIQALCSAQQLLQKTNDYRVFEN-- 113
            ....|..:||   |.|:.:     :.|..|   :|.| |:..:.:..:.:.::....|:...|
Zfish    58 VYSDNNLIHDLFLHWAEKYGPVYRINTLHYVTIMVYC-PEATKTIMMSPKYIKDPFVYKQLFNLF 121

  Fly   114 ---WLCEGLFTS-GFEKWSHRRKIVMPAFNYTMIKQFVAVFEKQSRILLTNVAKFAESGDQIDFL 174
               :|..||.|: ..:.|..:|:|:.|||:.|.::..::.|::.|..|:..:.:.|.:.......
Zfish   122 GKRFLGNGLITAVDHDMWYRQRRIMDPAFSSTYLRSLISTFDEMSERLMDKLEEMANNKTPAVMH 186

  Fly   175 QLISCFTLDTICETALGVSVGSQSSAKSEYLDAVKSIL--VIIDKRLKNIFYRNSFIFKRTSHYK 237
            .|::|.|||.||:.|.||.:...:...|.:.:||:..|  :|:|  :::.|:|         .:.
Zfish   187 DLVNCVTLDVICKVAFGVDLNLLNQKDSPFQNAVELCLKGMILD--VRDPFFR---------LFP 240

  Fly   238 REQELIKTLHGFTEGIIQKRIDEINQDAENRNYQSSDAELDGVKRTLCFLDTLLLSKGPDGKPLT 302
            :..:||:.:...|| :::|..::..|:.:.......|...|        :.|.:|....:.....
Zfish   241 KNWKLIQQVREATE-LLRKTGEKWIQNRKTAVKNGEDVPKD--------ILTQILKSAEEENVNN 296

  Fly   303 VKDIREEVD---TIIFGGFDLTATTLNFFMYNMTLHPEHQQRCREEVWSVCGKDKSEPISIEQVR 364
            .:|:.:.:|   |....|.:.||..|:|.:..:..:||..:|.:.||..|.|..:.  ||.|.:.
Zfish   297 TQDLEQMLDNFVTFFIAGQETTANQLSFAIMALGRNPEIYKRAKAEVDEVLGTKRE--ISNEDLG 359

  Fly   365 QLEFLEACIKETLRMYPSGPLTARKATANCTINDFFIPKGSDVIISPIYMGRCKDFFPDPMVFKP 429
            :|.:|...:|||||:||:.|.|.|....:..||...:|:|..|:.|.....|.:.||.||:.|.|
Zfish   360 KLTYLSQVLKETLRLYPTAPGTNRWLHEDIVINGIKVPRGCSVMFSSYVSQRLEKFFKDPLKFDP 424

  Fly   430 DRWAIGAEPKIEATTFIPFMAGARSCMGQRYAMVMLKMVLAHLLRNFLFEPLGERQVKLKLNFVI 494
            :|:.:.| || ....:.||..|.|:|:||.:|.:..|:|||.||:.|.|..:..:...:|.|.
Zfish   425 ERFDVNA-PK-PYYCYYPFSLGPRTCLGQVFAQMEAKLVLAKLLQRFEFSLVPGQSFDIKDNG-- 485

  Fly   495 TLHTVEPYLCRAK 507
            ||......:|..|
Zfish   486 TLRPKSGVICNIK 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp312a1	NP_001262008.1	p450	35..505	CDD:278495	131/492 (27%)
cyp46a1.1	NP_001018358.1	p450	39..495	CDD:278495	131/491 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D825914at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010