DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp312a1 and Cyp313a5

DIOPT Version :9

Sequence 1:	NP_001262008.1	Gene:	Cyp312a1 / 40005	FlyBaseID:	FBgn0036778	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_650168.1	Gene:	Cyp313a5 / 41486	FlyBaseID:	FBgn0038005	Length:	487	Species:	Drosophila melanogaster

Alignment Length:	480	Identity:	113/480 - (23%)
Similarity:	224/480 - (46%)	Gaps:	39/480 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 FGLLLLALSLYLLYVFERQSRIDRLTHKWPAPPALPFIG----HLHILAKLVGPHPLRRATEMIN 66
            |....:.|.:|.|:   .:.|...:..|.|.|...||||    ::.:..|      :|..|.:..
  Fly     7 FEAFAIILCVYFLW---SRRRFYIMMLKLPGPMGFPFIGLAFEYIRLKRK------IRLRTILFK 62

  Fly    67 EHLHDHRAKLWMGTKLYLVDCNPKDIQALCSAQQLLQKTNDY-RVFENWLCEGLFTSGFEKWSHR 130
              ::......|:|....||.|.||.::.:.::.....:::.. :...:.|..||.|.....|:.|
  Fly    63 --IYGKTVLTWIGLTPVLVTCEPKILEDIFTSPNCSNRSSVVDKAISSCLGLGLLTLKNNHWNER 125

  Fly   131 RKIVMPAFNYTMIKQFVAVFEKQSRILLTNVAKFAESGDQIDFLQLISCFTLDTICETALGVSVG 195
            ||:::|:|....:..||.|...::..|:|.:|:|.:.|| |:.|..::.::.....:..:|..|.
  Fly   126 RKLLLPSFKNNAVLSFVPVLNNEANFLVTLLAEFVDGGD-INLLPELNKWSFKIAAQITMGDEVR 189

  Fly   196 SQSSAKS-EYLDAVKSILVIIDKRLKNIFYRNSFIFKRTSHYKREQELIKTLHGFTEGIIQKRID 259
            :|::.:: ..|::.|::..:|...:...:.||.::.|..|:.||..|.....:.|.:.||.|::.
  Fly   190 NQANYQNGNLLESYKALNNLIPIGVVMPWLRNKYLGKLFSYEKRRLEAATQSNAFIKDIIDKKLS 254

  Fly   260 EINQDAENRNYQSSDAELDGVKRTLCFLDTLLLSKGPDGKPLTVKDIREEVDTIIFGGFDLTATT 324
            ..:..:|       .|.:|.:      |:.:.:.:      |:..|:..|...|||...|..:.|
  Fly   255 STDNSSE-------PALIDRI------LNLVRIGE------LSYDDVMGEFSNIIFAASDTLSIT 300

  Fly   325 LNFFMYNMTLHPEHQQRCREEVWSVCGKDKSEPISIEQVRQLEFLEACIKETLRMYPSGPLTARK 389
            :|..:..|.:.|::|....||:..|.........|...:.:|..|:..:.||:|:.|:.||..|:
  Fly   301 VNNVLILMAMFPKYQDNVFEELAEVFPSGGEFEASHADLEKLVKLDRVLHETMRLIPAVPLLIRQ 365

  Fly   390 ATANCTI-NDFFIPKGSDVIISPIYMGRCKDFF-PDPMVFKPDRWAIGAEPKIEATTFIPFMAGA 452
            .:.:..: |.|:||:|..::|...:..|.||.: |....|.||.:....:......:::||..|.
  Fly   366 TSHSIQLSNGFYIPEGVTLMIDIFHTHRNKDIWGPQANAFNPDNFLPENKRARPPYSYLPFSKGK 430

  Fly   453 RSCMGQRYAMVMLKMVLAHLLRNFL 477
            ::|:|.:.:::..|:.||.:|||::
  Fly   431 KTCLGWKLSLISAKLALAKILRNYM 455

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp312a1	NP_001262008.1	p450	35..505	CDD:278495	107/451 (24%)
Cyp313a5	NP_650168.1	p450	33..458	CDD:299894	107/451 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D825914at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.870