Protein Alignment Cyp312a1 and Cyp4p2

DIOPT Version :9

• Sequence 1: NP_001262008.1
• Gene: Cyp312a1 / 40005
• FlyBaseID: FBgn0036778
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_610472.1
• Gene: Cyp4p2 / 35946
• FlyBaseID: FBgn0033395
• Length: 520
• Species: Drosophila melanogaster
• Alignment Length: 525
• Identity: 143/525 - (27%)
• Similarity: 254/525 - (48%)
• Gaps: 56/525 - (10%)

  Fly     1 MFWLGFGLLLLALSLY-------LLYVFERQSRIDRLTHKWPAPPALPFIGHLHILAK---LVGP 55
            :.|:...:|::...:|       :|..|.|  |:.....| |....:|.|....:.|.   |:|
  Fly     5 LLWISVAILVVIHWIYKVNKDYNILAFFAR--RVQTKDGK-PLDSLVPMIKGRTVFANCFDLLG- 65

  Fly    56 HPLRRATEMINEHLH-------DHRAKLWMG-TKLYLVDCNPKDIQALCSAQQLLQKTNDYRVFE 112
                :.|:.:..||.       |...:..|| :...::|.:  :...:.:...|:.|...|....
  Fly    66 ----KDTDQVFTHLRQLAKNSGDSYLQYSMGFSNFNVIDAH--NAANILNHPNLITKGVIYNFLH 124

  Fly   113 NWLCEGLFTSGFEKWSHRRKIVMPAFNYTMIKQFVAVFEKQSRILLTNVAKFAESGDQIDFLQ-L 176
            .:|..|:.|:..:||..||.::...|:..::.||..:|..:|   |..|::|....:.:..|: .
  Fly   125 PFLRTGVLTATEKKWHTRRSMLTRTFHLDILNQFQEIFIAES---LKFVSQFQGQNEVVVSLKDR 186

  Fly   177 ISCFTLDTICETALGVSVGSQSSAKSEYLDAVKSILVIID----KRLKNIFYRNSFIFKRTSHYK 237
            ||.|||::|||||:|:.:...:.....|    ::...|||    :|:.|..|.:..::...:.:|
  Fly   187 ISRFTLNSICETAMGIKLDEMAEKGDRY----RANFHIIDEGLTRRIVNPLYWDDCVYNMFTGHK 247

  Fly   238 REQELIKTLHGFTEGIIQKRIDEINQDAENRN-YQSSDAELDGV-KRTLCFLDTLLLSKGPDGKP 300
            ....| |.:|.|:..||.||...:.::.|||. .|::|.::..: |:....||||:.:: .||
  Fly   248 YNAAL-KVVHEFSREIIAKRRVLLEEELENRRATQTADDDICVIRKKRFAMLDTLICAE-KDG-- 308

  Fly   301 LTVKD--IREEVDTIIFGGFDLTATTLNFFMYNMTLHPEHQQRCREEVWSVCGKDKSEPISIEQV 363
             .:.|  |.|||||::..|:|.|:..|.|.:.||:|:...|:.|.:|:......|.|. :::.|:
  Fly   309 -LIDDIGISEEVDTLMAEGYDTTSIGLVFGLMNMSLYAAEQELCYQEIQEHILDDLSN-LNLSQL 371

  Fly   364 RQLEFLEACIKETLRMYPSGPLTARKATANCTI-NDFFIPKGSDVIISPIYMGRCKDFFPDPMVF 427
            .:|.:|...||||:|:|||.|:..|:......: |...:||.|.:.|....:.|...::..|..|
  Fly   372 SKLNYLGYFIKETMRLYPSIPIMGRQTLQETELENGLILPKRSQINIHVFDIHRNPKYWESPEEF 436

  Fly   428 KPDRWAIGAEPKIEATTFIPFMAGARSCMGQRYAMVMLKMVLAHLLRNFLFEPLGER-----QVK 487
            :|:|:......|.....:|||.||.|:|:||:|||..:|.::..:|::|...|:.:.     ||.
  Fly   437 RPERFLPQNCLKRHPYAYIPFSAGQRNCIGQKYAMQEMKTLMVVILKHFKILPVIDPKSIVFQVG 501

  Fly   488 LKLNF 492
            :.|.|
  Fly   502 ITLRF 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp312a1	NP_001262008.1	p450	35..505	CDD:278495	135/484 (28%)
Cyp4p2	NP_610472.1	p450	63..514	CDD:299894	131/464 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460541
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24291
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
	7	6.990