Protein Alignment Cyp312a1 and Cyp4d1

DIOPT Version :10

• Sequence 1: NP_649030.1
• Gene: Cyp312a1 / 40005
• FlyBaseID: FBgn0036778
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_476907.2
• Gene: Cyp4d1 / 31188
• FlyBaseID: FBgn0005670
• Length: 512
• Species: Drosophila melanogaster
• Alignment Length: 510
• Identity: 205/510 - (40%)
• Similarity: 318/510 - (62%)
• Gaps: 21/510 - (4%)

  Fly    10 LLALSLY---LLYVFERQSRIDRLTHKWPAPPALPFIGHLHILAKLVG--PHPL-RRATEMINEH 68
            :||.:|:   |||..:.:..||.::: .|.||.||.:||.|   ..:|  ||.: ::..|.:..:
  Fly     8 ILASALFVGLLLYHLKFKRLIDLISY-MPGPPVLPLVGHGH---HFIGKPPHEMVKKIFEFMETY 68

  Fly    69 LHDHRAKLWMGTKLYLVDCNPKDIQALCSAQQLLQKTNDYRVFENWLCEGLFTSGFEKWSHRRKI 133
            ..|...|:|:|.:|.::..||||::.:....:...|..:|:..|.||.|||..|...||..||||
  Fly    69 SKDQVLKVWLGPELNVLMGNPKDVEVVLGTLRFNDKAGEYKALEPWLKEGLLVSRGRKWHKRRKI 133

  Fly   134 VMPAFNYTMIKQFVAVFEKQSRILLTNV----AKFAESGDQI-DFLQLISCFTLDTICETALGVS 193
            :.|||::.::.|||.||||.||.||.|:    .|..:||..: |::.|  | |:|||||||:|||
  Fly   134 ITPAFHFKILDQFVEVFEKGSRDLLRNMEQDRLKHGDSGFSLYDWINL--C-TMDTICETAMGVS 195

  Fly   194 VGSQSSAKSEYLDAVKSILVIIDKRLKNIFYRNSFIFKRTSHYKREQELIKTLHGFTEGIIQKRI 258
            :.:||:|.|||:.|||:|.:::.||:.||.||....:..|...:.|::.:..||.|||.||.:|.
  Fly   196 INAQSNADSEYVQAVKTISMVLHKRMFNILYRFDLTYMLTPLARAEKKALNVLHQFTEKIIVQRR 260

  Fly   259 DEINQDAENRNYQSSDAELDGVKRTLCFLDTLLLSKGPDGKPLTVKDIREEVDTIIFGGFDLTAT 323
            :|:.::..::...:.||:: |.||.:.||| :||....|.:||:..||||||||.:|.|.|.|::
  Fly   261 EELIREGSSQESSNDDADV-GAKRKMAFLD-ILLQSTVDERPLSNLDIREEVDTFMFEGHDTTSS 323

  Fly   324 TLNFFMYNMTLHPEHQQRCREEVWSVCGKDKSEPISIEQVRQLEFLEACIKETLRMYPSGPLTAR 388
            .|.||.||:..|||.|::|.||:.||.|.|||.|:|.|.:.||.:::.|:|||||||||.||..|
  Fly   324 ALMFFFYNIATHPEAQKKCFEEIRSVVGNDKSTPVSYELLNQLHYVDLCVKETLRMYPSVPLLGR 388

  Fly   389 KATANCTINDFFIPKGSDVIISPIYMGRCKDFFPDPMVFKPDRW-AIGAEPKIEATTFIPFMAGA 452
            |...:|.||...||.|:::.|||:|:||.::.|.:|.:|||:|: .:....|:....:|||.||.
  Fly   389 KVLEDCEINGKLIPAGTNIGISPLYLGRREELFSEPNIFKPERFDVVTTAEKLNPYAYIPFSAGP 453

  Fly   453 RSCMGQRYAMVMLKMVLAHLLRNFLFEPLGERQVKLKLNFVITLHTVEPYLCRAK 507
            |:|:||::||:.:|.::|::||::..:.:|:......|...:.|.|.||.:.:.:
  Fly   454 RNCIGQKFAMLEIKAIVANVLRHYEVDFVGDSSEPPVLIAELILRTKEPLMFKVR 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp312a1	NP_649030.1	CYP4	75..504	CDD:410721	184/434 (42%)
Cyp4d1	NP_476907.2	CYP4	73..504	CDD:410721	184/435 (42%)