Protein Alignment Cyp312a1 and Cyp4f39

DIOPT Version :10

• Sequence 1: NP_649030.1
• Gene: Cyp312a1 / 40005
• FlyBaseID: FBgn0036778
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: XP_234837.3
• Gene: Cyp4f39 / 299566
• RGDID: 1308796
• Length: 550
• Species: Rattus norvegicus
• Alignment Length: 526
• Identity: 148/526 - (28%)
• Similarity: 260/526 - (49%)
• Gaps: 44/526 - (8%)

  Fly     1 MFWLGFGLLLLALSLYLLYVFERQSRIDRLTHK----WPAPPALPF-IGHLHILAKLVGPHPLRR 60
            :.:|.|.|||.|..|:..:         |:|.:    :|.||...: :||:.:.  |.....|:.
  Rat    31 LLFLLFRLLLQAFKLFSDF---------RITCRRLSCFPEPPGRHWLLGHMSMY--LPNEKGLQN 84

  Fly    61 ATEMINEHLHDHRAKLWMGTKL-YLVDCNPKDIQALCSAQQLLQKTND--YRVFENWLCEGLFTS 122
            ..::: :.:| |....|:|..| .||..:|..|:.:..|...:...::  |...:.||.:||..|
  Rat    85 EKKVL-DTMH-HIILAWVGPFLPLLVLVHPDYIKPVLGASAAIAPKDEFFYSFLKPWLGDGLLIS 147

  Fly   123 GFEKWSHRRKIVMPAFNYTMIKQFVAVFEKQSRILLTNVAKFAESGD--QIDFLQLISCFTLDTI 185
            ...|||..|:::.|||::.::|.::.:|.:...|:.....:....|.  ..|..:.:|..|||::
  Rat   148 KGNKWSRHRRLLTPAFHFDILKPYMKIFNQSVNIMHAKWRRHLAEGSVTSFDMFEHVSLMTLDSL 212

  Fly   186 CETALGVSVGSQSSAKSEYLDAVKSILVIIDKRLKNIFYRNSFIFKRTSHYKREQELIKTLHGFT 250
            .:.....|...|... |:|:.::..:..::.:|...:.:...||:..|:..:|.::...|:|.||
  Rat   213 QKCVFSYSSDCQEKL-SDYISSIIELSALVVRRQYRLHHYLDFIYYLTADGRRFRQACDTVHNFT 276

  Fly   251 EGIIQKR---IDEINQDAENRNYQSSDAELDGVKRTLCFLDTLLLSKGPDGKPLTVKDIREEVDT 312
            ..:||:|   :.|:..:|..:..|.         :||.|:|.|||:|..:||.|:.:|||.|.||
  Rat   277 TEVIQQRRRALRELGAEAWLKAKQG---------KTLDFIDVLLLAKDEEGKELSDEDIRAEADT 332

  Fly   313 IIFGGFDLTATTLNFFMYNMTLHPEHQQRCREEVWSVCGKDKSEPISIEQVRQLEFLEACIKETL 377
            .:|.|.|.|::.|::.::|:..:||:|.:||||:..|....:.|.:..:.:.||.|...||||:|
  Rat   333 FMFEGHDTTSSGLSWALFNLAKYPEYQDKCREEIQEVMKGRELEELDWDDLTQLPFTTMCIKESL 397

  Fly   378 RMYPSGPLTARKATANCTIND-FFIPKGSDVIISPIYMGRCKDF-FPDPMVFKPDRWAIGAEPKI 440
            |.:|...|.:|:.|.:..:.| ..||||...::| ||....... :||..|:.|.|:......:.
  Rat   398 RQFPPVTLISRRCTEDIKLPDGRIIPKGIICLVS-IYGTHYNPLVWPDSKVYNPYRFDPDIPQQR 461

  Fly   441 EATTFIPFMAGARSCMGQRYAMVMLKMVLAHLLRNFLFEPLGERQVKLKLNFVITLH-----TVE 500
            ....|:||.||.|:|:||.:||..:::|:|..|..|.......|:|:.|...::...     .||
  Rat   462 SPLAFVPFSAGPRNCIGQSFAMAEMRVVVALTLLRFRLSVDRTRKVRRKPELILRTENGLWLNVE 526

  Fly   501 PYLCRA 506
            |...||
  Rat   527 PLPSRA 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp312a1	NP_649030.1	CYP4	75..504	CDD:410721	128/443 (29%)
Cyp4f39	XP_234837.3	CYP4F	82..523	CDD:410772	128/453 (28%)