Protein Alignment Cyp312a1 and Cyp4f6

DIOPT Version :10

• Sequence 1: NP_649030.1
• Gene: Cyp312a1 / 40005
• FlyBaseID: FBgn0036778
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: XP_006241111.1
• Gene: Cyp4f6 / 266689
• RGDID: 708365
• Length: 538
• Species: Rattus norvegicus
• Alignment Length: 537
• Identity: 165/537 - (30%)
• Similarity: 255/537 - (47%)
• Gaps: 66/537 - (12%)

  Fly     4 LGFG--------LLLLA-----LSLYLLYVFERQSRIDRLTHKWPAPPALP--FIGHLHILAKLV 53
            ||.|        ||||.     |:..|.:::.......|| ..:|.||. |  |.|||.::..
  Rat    10 LGMGSLTASPWHLLLLGGASWILARILAWIYTFYDNCCRL-RCFPQPPK-PSWFWGHLTLMKN-- 70

  Fly    54 GPHPLRRATEMINEHLHDHRAKL----------WMGTK---LYLVDCNPKDIQALCSAQQLL--Q 103
                        ||......|.|          |:|..   |.||  :|..|..|..|...:  :
  Rat    71 ------------NEEGMQFIAHLGRNFRDIHLSWVGPVYPILRLV--HPNVIAPLLQASAAVAPK 121

  Fly   104 KTNDYRVFENWLCEGLFTSGFEKWSHRRKIVMPAFNYTMIKQFVAVFEKQSRILLTNVAKFAESG 168
            :...|...:.||.:||..|..|||:|.|:::.|||::.::|.:|.:|.|....:.....:....|
  Rat   122 EMTLYGFLKPWLGDGLLMSAGEKWNHHRRLLTPAFHFDILKSYVKIFNKSVNTMHAKWQRLTAKG 186

  Fly   169 D-QIDFLQLISCFTLDTICETALGVSVGSQSSAKSEYLDAVKSILVIIDKRLKNIFYRNSFIFKR 232
            . ::|..:.||..|||::.:.........|.| .|||:.|:..:..:|.||.:..|....|::..
  Rat   187 SARLDMFEHISLMTLDSLQKCIFSFDSNCQES-NSEYIAAILELSSLIVKRQRQPFLYLDFLYYL 250

  Fly   233 TSHYKREQELIKTLHGFTEGIIQKRIDEINQDAENRNYQSSDAELD--GVKRTLCFLDTLLLSKG 295
            |:..:|.::....:|.||:.:|::|...:|.       |..|..|.  ...:||.|:|.|||:|.
  Rat   251 TADGRRFRKACDVVHNFTDAVIRERRSTLNT-------QGVDEFLKARAKTKTLDFIDVLLLAKD 308

  Fly   296 PDGKPLTVKDIREEVDTIIFGGFDLTATTLNFFMYNMTLHPEHQQRCREEVWSVCGKDKSEPISI 360
            ..||.|:..|||.|.||.:|||.|.||:.|::.:||:..|||:|:|||:||..:....:.|.|..
  Rat   309 EHGKGLSDVDIRAEADTFMFGGHDTTASALSWILYNLARHPEYQERCRQEVRELLRDREPEEIEW 373

  Fly   361 EQVRQLEFLEACIKETLRMYPSGPLTARKATANCTIND-FFIPKGSDVIISPIYMGRCKDFFPDP 424
            :.:.||.||..||||:||::|...|.:|..:.:..:.| ..||||:..:||...:......:|||
  Rat   374 DDLAQLPFLTMCIKESLRLHPPVLLISRCCSQDIVLPDGRVIPKGNICVISIFGVHHNPSVWPDP 438

  Fly   425 MVFKPDRWAIGAEPKIEATTFIPFMAGARSCMGQRYAMVMLKMVLAHLLRNFLFEPLGERQVKLK 489
            .|:.|.|:......|.....||||.||.|:|:||.:||..:|:.||..|..|...| .:::.:.|
  Rat   439 EVYNPFRFDPENPQKRSPLAFIPFSAGPRNCIGQTFAMSEIKVALALTLLRFCVLP-DDKEPRRK 502

  Fly   490 LNFVITLH-----TVEP 501
            ...::...     .|||
  Rat   503 PELILRAEGGLWLRVEP 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp312a1	NP_649030.1	CYP4	75..504	CDD:410721	143/451 (32%)
Cyp4f6	XP_006241111.1	CYP4F	75..516	CDD:410772	141/451 (31%)