Protein Alignment Cyp312a1 and Cyp4a14

DIOPT Version :10

• Sequence 1: NP_649030.1
• Gene: Cyp312a1 / 40005
• FlyBaseID: FBgn0036778
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_031848.1
• Gene: Cyp4a14 / 13119
• MGIID: 1096550
• Length: 507
• Species: Mus musculus
• Alignment Length: 499
• Identity: 138/499 - (27%)
• Similarity: 232/499 - (46%)
• Gaps: 59/499 - (11%)

  Fly     5 GFGLLLLALSLYLL------YVFERQSRIDRLTHKWPAPPALPFIGHLHILAKLVGPHPLRRATE 63
            ||......|||:|:      :...||..:..|.| :|..|:....||
Mouse    17 GFFQWAFLLSLFLVLFKAVQFYLRRQWLLKTLQH-FPCMPSHWLWGH------------------ 62

  Fly    64 MINEHLHDHRAK---LWM------------GTKLYLVDCNPKDIQALCSAQQLLQKTNDYRVFEN 113
                ||.|...:   :|:            |:.:.::..:|..::.:..... .:.:..|:.|..
Mouse    63 ----HLKDKELQQILIWVEKFPSACLQCLSGSNIRVLLYDPDYVKVVLGRSD-PKASGIYQFFAP 122

  Fly   114 WLCEGLFTSGFEKWSHRRKIVMPAFNYTMIKQFVAVFEKQSRILLTNVAKFAESGDQIDFLQLIS 178
            |:..||.....:||...|:::.|||:|.::|.:|.:......|:|....|.......::....:|
Mouse   123 WIGYGLLLLNGKKWFQHRRMLTPAFHYDILKPYVKIMADSVNIMLDKWEKLDGQDHPLEIFHCVS 187

  Fly   179 CFTLDTICETALGVSVGSQSSAKSE-YLDAVKSILVIIDKRLKNIFYRNSFIFKRTSHYKREQEL 242
            ..||||:.:.|.......|....|: |..||:.:..:...||:|.||:.:.|:..:|..:.....
Mouse   188 LMTLDTVMKCAFSYQGSVQLDENSKLYTKAVEDLNNLTFFRLRNAFYKYNIIYNMSSDGRLSHHA 252

  Fly   243 IKTLHGFTEGIIQKRIDEINQDAENRNYQSSDAELDGVKRTLCFLDTLLLSKGPDGKPLTVKDIR 307
            .:..|..|:|:|:.|..::..:.|.:..:.        ||.|.|||.||.::..|...|:.:|:|
Mouse   253 CQIAHEHTDGVIKMRKSQLQNEEELQKARK--------KRHLDFLDILLFARMEDRNSLSDEDLR 309

  Fly   308 EEVDTIIFGGFDLTATTLNFFMYNMTLHPEHQQRCREEVWSVCGKDKSEPISIEQVRQLEFLEAC 372
            .||||.:|.|.|.||:.:::..|.:..||||||||||||.|:.|...|  ::.:.:.|:.:...|
Mouse   310 AEVDTFMFEGHDTTASGISWIFYALATHPEHQQRCREEVQSILGDGTS--VTWDHLGQMPYTTMC 372

  Fly   373 IKETLRMYPSGPLTARKATANCTIND-FFIPKGSDVIISPIYMGRCKDFFPDPMVFKPDRWAIGA 436
            |||.||:||.....:|:.::..|..| ..||||....||...:.....|:|:|.||.|.|:|  .
Mouse   373 IKEALRLYPPVISVSRELSSPVTFPDGRSIPKGITATISIYGLHHNPRFWPNPKVFDPSRFA--P 435

  Fly   437 EPKIEATTFIPFMAGARSCMGQRYAMVMLKMVLAHLLRNFLFEP 480
            :....:..::||..|:|:|:|:::||..||:.:|..|..|...|
Mouse   436 DSSHHSHAYLPFSGGSRNCIGKQFAMNELKVAVALTLLRFELLP 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp312a1	NP_649030.1	CYP4	75..504	CDD:410721	121/423 (29%)
Cyp4a14	NP_031848.1	CYP4B-like	69..502	CDD:410771	121/424 (29%)