Protein Alignment Cyp312a1 and Cyp4a32

DIOPT Version :9

• Sequence 1: NP_001262008.1
• Gene: Cyp312a1 / 40005
• FlyBaseID: FBgn0036778
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_001093651.1
• Gene: Cyp4a32 / 100040843
• MGIID: 3717148
• Length: 509
• Species: Mus musculus
• Alignment Length: 511
• Identity: 159/511 - (31%)
• Similarity: 254/511 - (49%)
• Gaps: 52/511 - (10%)

  Fly     7 GLLLLALSLYLLYVFERQSRIDRLTHKW--------PAPPALPFIGHLHILAKLVGPHPLRRATE 63
            |||||.:.....|          |..||        |:||...|.||    .:..|...|:....
Mouse    26 GLLLLLVKAVQFY----------LHRKWLLKALQQFPSPPFHWFFGH----EQFKGEQELKEVVS 76

  Fly    64 MINEHLHDHRAKLWMGTKLYLVDCNPKDIQALCSAQQLLQKTND-YRVFENWLCEGLFTSGFEKW 127
            .| ||........:.|:..||...:|..::.:.....  .|.|. ||:...|:..||.....:.|
Mouse    77 CI-EHFPSAFPCWFWGSNAYLTVYDPDYMKVILGRSD--PKANGIYRLLAPWIGYGLLLLNGQPW 138

  Fly   128 SHRRKIVMPAFNYTMIKQFVAVFEKQSRILLTNVAKFAESGDQIDFLQLISCFTLDTICETALG- 191
            ...|:::.|||:|.::|.:|.......|::|....:.|.....|:..|.||..||||:.:.|..
Mouse   139 FQHRRMLTPAFHYDILKPYVKNMADSIRLMLDKWERLAGQDSSIEIFQHISLMTLDTVMKCAFSH 203

  Fly   192 -VSVGSQSSAKSEYLDAVKSILVIIDKRLKNIFYRNSFIFKRTSHYKREQELIKTLHGFTEGIIQ 255
             .||....:.|: ||.|:..:..:...|::|||::|..|::.:|:.:..::..:..|..|:|:|:
Mouse   204 KGSVQVDGNYKT-YLQAIGDLNNLFHSRVRNIFHQNDTIYRLSSNGRLAKQACQLAHDHTDGVIK 267

  Fly   256 KRIDEINQDAENRNYQSSDAELDGVKRTLCFLDTLLLSKGPDGKPLTVKDIREEVDTIIFGGFDL 320
            .|.|::..:.|..|.:.        ||.|.|||.||.::..:|..::.||:|.||||.:|.|.|.
Mouse   268 MRKDQLQDEGELENIKK--------KRRLDFLDILLFARMENGDSMSDKDLRAEVDTFMFEGHDT 324

  Fly   321 TATTLNFFMYNMTLHPEHQQRCREEVWSVCGKDKSEPISIEQVRQLEFLEACIKETLRMYPSGPL 385
            ||:.:::..|.:..||||||||||||.|:.|...|  |:.:.:.|:.:...||||.||:||..|.
Mouse   325 TASGVSWIFYALATHPEHQQRCREEVQSLLGDGSS--ITWDHLDQIPYTTMCIKEALRLYPPVPG 387

  Fly   386 TARKATANCTIND-FFIPKGSDVIISPIYMGRCKDFFPDPMVFKPDRWAIGAEPKIEATTFIPFM 449
            ..|:.:.:.|..| ..:|||..|.:|...:......:|:|.||.|.|:|..: |: .:.:|:||.
Mouse   388 IVRELSTSVTFPDGRSLPKGVQVTLSIYGLHHNPKVWPNPEVFDPSRFAPDS-PR-HSHSFLPFS 450

  Fly   450 AGARSCMGQRYAMVMLKMVLAHLLRNF--------LFEPLGERQVKLKLNFVITLH 497
            .|||:|:|:::||..||:::|..|.:|        :.|||.  ::.||....|.||
Mouse   451 GGARNCIGKQFAMSELKVIVALTLLHFELLPDPTRVPEPLA--RIVLKSKNGIYLH 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp312a1	NP_001262008.1	p450	35..505	CDD:278495	150/475 (32%)
Cyp4a32	NP_001093651.1	p450	52..503	CDD:278495	148/472 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845133
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D214327at33208
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.750