Protein Alignment mus304 and Atrip

DIOPT Version :10

• Sequence 1: NP_524135.3
• Gene: mus304 / 40003
• FlyBaseID: FBgn0002901
• Length: 846
• Species: Drosophila melanogaster
• Sequence 2: NP_766362.2
• Gene: Atrip / 235610
• MGIID: 1925349
• Length: 785
• Species: Mus musculus
• Alignment Length: 821
• Identity: 160/821 - (19%)
• Similarity: 278/821 - (33%)
• Gaps: 239/821 - (29%)

  Fly    65 RKKKGGTEVDIGNSEVTFSEFAPTFQGSTSTQQMFPPPPPPQKKPTSLDMDAIFADDDDFDFLAV 129
            ||:.||.|...|.|...  |..|:.:..:.::...|.|..|..:......|    |.::.|.||.
Mouse    11 RKQSGGLEPFPGLSRSI--ENPPSKRARSFSETTVPDPEDPFGEHAEFTAD----DLEELDILAS 69

  Fly   130 TLMDSEPQKMPEPKTSTSRITTSSISVQQKTTTTTTINATQSRQQEHQLKFLMD--RIEALKREN 192
            ..:...|            :...::|...|......:..:..|:....:. :.|  .:|.|:.:.
Mouse    70 QALSQCP------------VAPRNLSSAHKVRRLDGLPNSPIRKSREDIP-VKDNFELEVLQIQY 121

  Fly   193 AQLEKNLGDSKERNEIKSGEVSLLRDELKHLRQQLQASKMEKLALADETNRDCNKKVAEAAKQIA 257
            .:|::.|...:|...||:||:.:|||.|:.....|:..|.....|..|..:..::|..|.::::.
Mouse   122 KELKEKLKAMEEEILIKNGEIKILRDSLRQTESVLEEQKRSHFLLEQEKTQALSEKEKEFSRKLQ 186

  Fly   258 AKDIELKIKNAEFSKLKTQQKAHERS--------------MNSSMSILQAAPDP------LEKRL 302
            :...||:.|:||.::|:|:.:::.|:              ..||:.:...|..|      ...:.
Mouse   187 SLQSELQFKDAEMNELRTKSQSNGRTNKPAAPSVSHVSPRKGSSVVLKSEACSPHVGKTTFPTKE 251

  Fly   303 SLRLNRLNIHRSVPGLKTDNGSVF----EYSENEDQTKKRRNH------FELELKQLLLHYARLQ 357
            |...|....|    ..:|:.|..|    |.|:|       :||      .:.:::|.:|....:|
Mouse   252 SFSANTPLFH----PCQTEAGHRFLVGQEVSDN-------KNHSLGGSLMKQDVQQRILADGWMQ 305

  Fly   358 AK-----------------------------------------PESVDNL-----LPRILSSVGK 376
            .|                                         |..:..|     |..|.||.|.
Mouse   306 RKDAQGSILINLLLKQPLVPGSSLGLCHLLSSCPEVPTGTLLQPPGLSTLPGTSGLRTISSSDGP 370

  Fly   377 VFTEFASYAQSLDF-----------PHN-----CMLYPYNPHNLEEEVHRI-------------- 411
            ........||:|.|           .|:     ..::|.  |.|...||.:
Mouse   371 FSPSALREAQNLAFTGLNLVARTESSHDGDMAGRRVFPL--HQLPGAVHLLPLVQFFVGLHCQAL 433

  Fly   412 --------------SLTHQSCLYDNEKAVPLRRFIATLALICRREERISRGLTEWKENDLGLLDM 462
                          |.||.||:....:|.|              |:.| .||..:....|.:|..
Mouse   434 QDLAPAKKSGVPGDSATHTSCMSSGVEASP--------------EDSI-HGLESFSVASLSVLQN 483

  Fly   463 ------AIEAITKLGFSYEVGQHFGLLEALTSLLNSLLQENALLQHNEELLFDLLKQLVFTRPSP 521
                  |:..:...|...|.....|.|....:...|..:|:|..|....||..||:.:..:..:.
Mouse   484 LVCHSGAVVCLLLSGMGTEAAAREGNLVQTCADTTSASREDAHDQDQHPLLKMLLQLMASSSAAS 548

  Fly   522 WVFAELSSCFLSCLRHPQLMDKMCVNSPKDCFVSDRVRSVYRFGPDSCLLQVYAGLLELCFFSET 586
            ..|.  :|....||:   ::.|:..|:..|.        :.||   ||:..|    |..|..|..
Mouse   549 GHFQ--ASVLGLCLK---VLVKLAENASSDL--------LPRF---SCVFPV----LPQCLGSAL 593

  Fly   587 PLRQDYFQL-LLKIGGNHVRFAFECFKNPPD-FILEMLPYFADDGDEDSSDGTLMKTGTSLSFNS 649
            ||......: ||.:..:|...|::...:|.. .:|.:..|.....|..:|:...::
Mouse   594 PLPCVLLAVELLSVLLDHDSLAWQLCSHPEGCLLLRLYMYITSRPDRTASETQWLQ--------- 649

  Fly   650 TGAVQGSVSNGSTSASVSNPNQNSNSSTTQRGKGCECYVKLCLSAVTIVFQVMHQWMLHSRKAG- 713
               ::..|.......||.:|      :....|..|.|.|: .:.|:|:   ::|:..|..|:||
Mouse   650 ---LEQEVVWLLAKLSVQSP------APAGIGSDCHCNVE-AVRALTV---MLHRQWLTVRRAGG 701

  Fly   714 --TEEVGEISR------IAVHLLSL-----------VFHEY 735
              |.:..:..|      :.:|.||.           |.|:|
Mouse   702 PRTHQQKQTIRCLRDTVLLLHSLSQKDKLFTVHCVEVLHQY 742

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mus304	NP_524135.3	DivIVA	<181..282	CDD:428304	27/102 (26%)
		COG4913	<183..>466	CDD:443941	78/410 (19%)
Atrip	NP_766362.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..53		12/43 (28%)
		Interaction with CINP. /evidence=ECO:0000250	118..156		11/37 (30%)
		ERM_helical	120..205	CDD:466641	23/84 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	201..227		3/25 (12%)
		EEXXXDL motif	763..770