Protein Alignment Eip75B and NR1I3

DIOPT Version :9

• Sequence 1: NP_001246821.1
• Gene: Eip75B / 39999
• FlyBaseID: FBgn0000568
• Length: 1412
• Species: Drosophila melanogaster
• Sequence 2: XP_005245750.1
• Gene: NR1I3 / 9970
• HGNCID: 7969
• Length: 429
• Species: Homo sapiens
• Alignment Length: 528
• Identity: 113/528 - (21%)
• Similarity: 185/528 - (35%)
• Gaps: 159/528 - (30%)

  Fly   329 HQAQQH-------QQQHQQHQQHQQH----VIASVSSSSSSSAIGSGGSSSSHIFRTP------- 375
            |:...|       ..||..|.....|    ..:.|.:.:..|...:||    ||.:|.
Human     3 HKVPTHWSPSPCATNQHFCHAGKTSHPGLCPESRVCALTPQSLRATGG----HIKQTSLVFQILR 63

  Fly   376 -VVSSSSSSNMHHQQQQQQQQSSLGN----SVMRPPPPPPPPKVKHASSSSSGNSSSSNTNNSSS 435
             ::.:|:...:...::.|||:.|||.    .::.|.....|.:.:...|.|.|
Human    64 VIIPNSNHWQLLRSEENQQQRGSLGRGIPYQILWPAGDMLPKRSRRTVSKSIG------------ 116

  Fly   436 SSNGEEPSSSIPDLEFDGTTVLCRVCGDKASGFHYGVHSCEGCKGFFRRSIQQKIQYRPCTKNQQ 500
                       |...|.|:
Human   117 -----------PTCPFAGS---------------------------------------------- 124

  Fly   501 CSILRINRNRCQYCRLKKCIAVGMSRDAVRFGRVPKREKARILAAMQ-QSTQNRGQQRALATELD 564
            |.:.:..|..|..|||:||:..||.:|.:.        .|..||..: :..|.|.||..:... .
Human   125 CEVSKTQRRHCPACRLQKCLDAGMRKDMIL--------SAEALALRRAKQAQRRAQQTPVQLS-K 180

  Fly   565 DQPRLLAAVLRAHLETCEFTKEKVSAMRQRARDCP-------SYSMPTLLACPLNPAPELQSEQE 622
            :|..|:..:|.||      |:...:...|..:..|       ...:|||       ||.|.....
Human   181 EQEELIRTLLGAH------TRHMGTMFEQFVQFRPPAHLFIHHQPLPTL-------APVLPLVTH 232

  Fly   623 FSQRFAHVIRGVIDFAGMIPGFQLLTQDDKFTLLKAGLFDALFVRLICMFDSSINSIICLNGQVM 687
            |:.....::..||.|...:|.|:.|..:|:.:|||....:      ||..  .:|:..||..|..
Human   233 FADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVE------ICHI--VLNTTFCLQTQNF 289

  Fly   688 ----RRDAIQNGA--------NARFLVDSTFNFAERMNSMNLTDAEIGLFCAIVLITP-----DR 735
                .|..|::||        ...|| :..|:|...:..:.|.:.|..|..|:.|.:|     ||
Human   290 LCGPLRYTIEDGARVSPTVGFQVEFL-ELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDR 353

  Fly   736 PGLRNLELIEKMYSRLKGCLQ-YIVAQNRPDQPEFL-AKLLETMPDLRTLSTLHTEKLVVFRTEH 798
            ||:...:.|:::...:...|| ||..|.|..:..|| ||||..:.:||:::..:.     ::.:|
Human   354 PGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYG-----YQIQH 413

  Fly   799 KELLRQQM 806
            .:.|...|
Human   414 IQGLSAMM 421

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eip75B	NP_001246821.1	NR_DBD_REV_ERB	453..541	CDD:143540	12/87 (14%)
		NR_LBD_REV_ERB	609..796	CDD:132738	53/205 (26%)
NR1I3	XP_005245750.1	NR_DBD_like	<108..154	CDD:295381	17/114 (15%)
		NR_LBD_PXR_like	178..427	CDD:132732	67/272 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910