Protein Alignment Eip75B and NR1I2

DIOPT Version :9

• Sequence 1: NP_001246821.1
• Gene: Eip75B / 39999
• FlyBaseID: FBgn0000568
• Length: 1412
• Species: Drosophila melanogaster
• Sequence 2: NP_071285.1
• Gene: NR1I2 / 8856
• HGNCID: 7968
• Length: 473
• Species: Homo sapiens
• Alignment Length: 467
• Identity: 115/467 - (24%)
• Similarity: 201/467 - (43%)
• Gaps: 70/467 - (14%)

  Fly   386 HHQQQQQQQQSSLGNSVMRPPPPPPPPKVKHASSSSSGNSSSSNTNNSSSSSNGE----EPSSSI 446
            ||.::         .|:..|..|......:.||:...|..::.......|.::.:    |.:.|:
Human     7 HHFKE---------GSLRAPAIPLHSAAAELASNHPRGPEANLEVRPKESWNHADFVHCEDTESV 62

  Fly   447 P-------DLEFDGTTVLCRVCGDKASGFHYGVHSCEGCKGFFRRSIQQKIQYRPCTKNQQCSIL 504
            |       |.|..|..: ||||||||:|:|:.|.:||||||||||::::..:.|...:...|.|.
Human    63 PGKPSVNADEEVGGPQI-CRVCGDKATGYHFNVMTCEGCKGFFRRAMKRNARLRCPFRKGACEIT 126

  Fly   505 RINRNRCQYCRLKKCIAVGMSRDAVRFGRVPKREKARILAAMQQ--STQNRG------QQRALAT 561
            |..|.:||.|||:||:..||.::.:......:..:|.|.....:  .||..|      :||.:..
Human   127 RKTRRQCQACRLRKCLESGMKKEMIMSDEAVEERRALIKRKKSERTGTQPLGVQGLTEEQRMMIR 191

  Fly   562 ELDDQPRLLAAVLRAHLET----------CEFTKEKVSAMRQRARDCPSYSMPTLLACPLNPAPE 616
            ||.|..........:|.:.          ||..:...:..|:.|   ..:|......|.|..:.:
Human   192 ELMDAQMKTFDTTFSHFKNFRLPGVLSSGCELPESLQAPSREEA---AKWSQVRKDLCSLKVSLQ 253

  Fly   617 LQSEQ----------------------EFSQRFAHVIRGVIDFAGMIPGFQLLTQDDKFTLLKAG 659
            |:.|.                      ..:....::.:|:|.||.:|..|:.|..:|:.:|||..
Human   254 LRGEDGSVWNYKPPADSGGKEIFSLLPHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLLKGA 318

  Fly   660 LFDALFVRLICMFDSSINSIICLNGQVMRRDAIQNGANARFLVDSTFNFAERMNSMNLTDAEIGL 724
            .|:...:|...:|::...:..|........|..  |...:.|::....|...:..:.|.:.|..|
Human   319 AFELCQLRFNTVFNAETGTWECGRLSYCLEDTA--GGFQQLLLEPMLKFHYMLKKLQLHEEEYVL 381

  Fly   725 FCAIVLITPDRPGLRNLELIEKMYSRLKGCLQYIVAQNRPDQP--EFL-AKLLETMPDLRTLSTL 786
            ..||.|.:|||||:....:::::..:....|:..:..||| ||  .|| .|::..:.:||:::..
Human   382 MQAISLFSPDRPGVLQHRVVDQLQEQFAITLKSYIECNRP-QPAHRFLFLKIMAMLTELRSINAQ 445

  Fly   787 HTEKLVVFRTEH 798
            ||::|:..:..|
Human   446 HTQRLLRIQDIH 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eip75B	NP_001246821.1	NR_DBD_REV_ERB	453..541	CDD:143540	36/87 (41%)
		NR_LBD_REV_ERB	609..796	CDD:132738	48/211 (23%)
NR1I2	NP_071285.1	NR_DBD_PXR	79..166	CDD:143536	37/87 (43%)
		NR_LBD_PXR_like	182..467	CDD:132732	60/282 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910