Protein Alignment Eip75B and Nr1i2

DIOPT Version :9

• Sequence 1: NP_001246821.1
• Gene: Eip75B / 39999
• FlyBaseID: FBgn0000568
• Length: 1412
• Species: Drosophila melanogaster
• Sequence 2: NP_443212.1
• Gene: Nr1i2 / 84385
• RGDID: 69057
• Length: 431
• Species: Rattus norvegicus
• Alignment Length: 424
• Identity: 118/424 - (27%)
• Similarity: 197/424 - (46%)
• Gaps: 66/424 - (15%)

  Fly   440 EEPSSSIPDLEFDGTTVLCRVCGDKASGFHYGVHSCEGCKGFFRRSIQQKIQYRPCTKNQQCSIL 504
            |||   |...|.||...:||||||||:|:|:.|.:||||||||||::::.::.|...:...|.|.
  Rat    23 EEP---INVDEEDGGLQICRVCGDKANGYHFNVMTCEGCKGFFRRAMKRNVRLRCPFRKGTCEIT 84

  Fly   505 RINRNRCQYCRLKKCIAVGMSRDAV--------RFGRVPKREKARILAAMQQSTQNRGQQRALAT 561
            |..|.:||.|||:||:..||.::.:        |...:.::::.:|.|..........:|:||..
  Rat    85 RKTRRQCQACRLRKCLESGMKKEMIMSDAAVEQRRALIKRKKREKIEAPPPGGQGLTEEQQALIQ 149

  Fly   562 ELDDQPRLLAAVLRAHLETCEFTKEKVSAMRQRA---RDC--PSYSMPTLL------------AC 609
            ||.|          |.::|.:.|.......|..|   .||  |.....:||            :.
  Rat   150 ELMD----------AQMQTFDTTFSHFKDFRLPAVFHSDCELPEVLQASLLEDPATWSQIMKDSV 204

  Fly   610 PLNPAPELQSE---------------QEFSQRFAH-------VIRGVIDFAGMIPGFQLLTQDDK 652
            |:..:.:|:.|               :|......|       :.:|||:||.:|..|:.|..:|:
  Rat   205 PMKISVQLRGEDGSIWNYQPPSKSDGKEIIPLLPHLADVSTYMFKGVINFAKVISHFRELPIEDQ 269

  Fly   653 FTLLKAGLFDALFVRLICMFDSSINSIICLNGQVMRRDAIQNGANARFLVDSTFNFAERMNSMNL 717
            .:|||...|:...:|...|||:...:..|  |::.......||...:.|:|....|...:..:.|
  Rat   270 ISLLKGATFEMCILRFNTMFDTETGTWEC--GRLAYCFEDPNGGFQKLLLDPLMKFHCMLKKLQL 332

  Fly   718 TDAEIGLFCAIVLITPDRPGLRNLELIEKMYSRLKGCLQYIVAQNRP-DQPEFL-AKLLETMPDL 780
            .:.|..|..||.|.:|||||:....:::::..|....|:..:..:|| ....|| .|::..:.:|
  Rat   333 REEEYVLMQAISLFSPDRPGVVQRSVVDQLQERFALTLKAYIECSRPYPAHRFLFLKIMAVLTEL 397

  Fly   781 RTLSTLHTEKLVVFRTEH--KELLRQQMWSMEDG 812
            |:::...|::|:..:..|  ...|.|:::|..||
  Rat   398 RSINAQQTQQLLRIQDTHPFATPLMQELFSSTDG 431

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eip75B	NP_001246821.1	NR_DBD_REV_ERB	453..541	CDD:143540	37/95 (39%)
		NR_LBD_REV_ERB	609..796	CDD:132738	51/210 (24%)
Nr1i2	NP_443212.1	NR_DBD_like	37..124	CDD:413390	36/86 (42%)
		Bipartite nuclear localization signal. /evidence=ECO:0000250	63..89		6/25 (24%)
		Hinge	105..142		3/36 (8%)
		NR_LBD	140..425	CDD:416257	70/296 (24%)
		Hyperforin binding, agonist. /evidence=ECO:0000250|UniProtKB:O75469	282..285		0/2 (0%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910