Protein Alignment Eip75B and nr1d4b

DIOPT Version :9

• Sequence 1: NP_001246821.1
• Gene: Eip75B / 39999
• FlyBaseID: FBgn0000568
• Length: 1412
• Species: Drosophila melanogaster
• Sequence 2: NP_001272462.1
• Gene: nr1d4b / 571948
• ZFINID: ZDB-GENE-080403-6
• Length: 576
• Species: Danio rerio
• Alignment Length: 595
• Identity: 191/595 - (32%)
• Similarity: 265/595 - (44%)
• Gaps: 182/595 - (30%)

  Fly   354 SSSSSSAIGSGGSSSSHIFRTPVVSSSSSSNMHHQQQQQQQQSSLGNSVMRPPPPPPPPKVKHAS 418
            :.|:.||..|.||.||. ::|...||..||        .::.|..|...::          ||:|
Zfish    12 AGSTGSASPSPGSPSSG-YQTQSPSSQPSS--------PEEVSFTGLGALK----------KHSS 57

  Fly   419 SSSSGNS--------SSSNTNN------SSSSSN-------GEEPSSSIPDLEFDGT-------T 455
            ..:.||.        ||:||.|      :||..|       |..|:.      |.||       .
Zfish    58 GGNGGNKLVFQFPEVSSANTVNAVTPTVTSSGQNSYSHPMVGRRPTG------FTGTFTKTGGMV 116

  Fly   456 VLCRVCGDKASGFHYGVHSCEGCKGFFRRSIQQKIQYRPCTKNQQCSILRINRNRCQYCRLKKCI 520
            :||:||||.|||||||||:||||||||||||||.|.|:.|.||:.|.|:|:||||||:||.|||:
Zfish   117 LLCKVCGDIASGFHYGVHACEGCKGFFRRSIQQNIHYKMCVKNENCLIMRMNRNRCQHCRFKKCL 181

  Fly   521 AVGMSRDAVRFGRVPKREKARILAAMQQ----------------------STQNRGQQ------- 556
            :||||||||||||:|||||.|:|..||.                      |:...||.
Zfish   182 SVGMSRDAVRFGRIPKREKQRLLDEMQSYMNSLNESASMDIGCTTPTETPSSPEDGQSEESIGVI 246

  Fly   557 -----------RALATELDD----------------------------QPRLLAAVLRAHLETCE 582
                       ..|..::|.                            ||.:.|.....|..|..
Zfish   247 SQAYRNIFVNGEKLQVKVDQENNVNNNNNPSSFRHHPMQESGYVQSHPQPNISAQEHSVHSTTSC 311

  Fly   583 FTKEKVSAMRQRAR----------------------DCPSYSMPT-------------------- 605
            ..:.:.....|..:                      ..|:.|.||
Zfish   312 LAQSRCPVANQNNKPTSQVLDNGHYNFPQSSSPSQGTTPTQSYPTKHNSYSTQTQSCPWRLSPGA 376

  Fly   606 -LLACPLNPAP-------ELQSEQEFSQRFAHVIRGVIDFAGMIPGFQLLTQDDKFTLLKAGLFD 662
             :||||||..|       ..|..:.|||.|...::.|::||..|||||.|:|.|:..|||||.|.
Zfish   377 KVLACPLNACPVSSASHSSQQVWESFSQCFTPAVKEVVEFAKSIPGFQALSQHDQVMLLKAGTFQ 441

  Fly   663 ALFVRLICMFDSSINSIICLNGQV-----MRRDAIQNGANARFLVDSTFNFAERMNSMNLTDAEI 722
            .|.||...:|::...::..||||.     :|...:.|      |:|:.|.|:|::.||.|...|:
Zfish   442 VLMVRFCSLFNAKERTVTFLNGQTYPLSYLRVLGMGN------LLDAMFEFSEKLGSMGLEADEM 500

  Fly   723 GLFCAIVLITPDRPGLRNLELIEKMYSRLKGCLQYIVAQNRPDQPEFLAKLLETMPDLRTLSTLH 787
            .||.|:||::.||.|:.::..:|::...|.|.|:.::.:.:|:......||...:||||||:..|
Zfish   501 ALFMAVVLVSADRSGISDMGAVEQLQEDLIGALRALITRRKPEDSSLFPKLPLRLPDLRTLNNQH 565

  Fly   788 TEKLVVFRTE 797
            :|||:.|..:
Zfish   566 SEKLLAFHID 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eip75B	NP_001246821.1	NR_DBD_REV_ERB	453..541	CDD:143540	67/94 (71%)
		NR_LBD_REV_ERB	609..796	CDD:132738	72/198 (36%)
nr1d4b	NP_001272462.1	NR_DBD_REV_ERB	115..202	CDD:143540	65/86 (76%)
		NR_LBD	386..574	CDD:299703	68/193 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	133	1.000	Domainoid score	I5003
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002268
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24082
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1497
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	6.010