Protein Alignment Eip75B and pparg

DIOPT Version :10

• Sequence 1: NP_730321.1
• Gene: Eip75B / 39999
• FlyBaseID: FBgn0000568
• Length: 1412
• Species: Drosophila melanogaster
• Sequence 2: NP_571542.2
• Gene: pparg / 557037
• ZFINID: ZDB-GENE-990415-213
• Length: 511
• Species: Danio rerio
• Alignment Length: 468
• Identity: 146/468 - (31%)
• Similarity: 224/468 - (47%)
• Gaps: 79/468 - (16%)

  Fly   371 IFRTPVVSSSSSSNMHHQQQQQQQQSSLGNSVMRPPPPPPPPKVKHASSSSSGNSSSSNTNNSSS 435
            |:|....|.|...|.:..||.|       ||:...|..||                ....|:.|.
Zfish    82 IYRPEHSSYSPEENTYRAQQIQ-------NSIKLEPESPP----------------QFAENSVSF 123

  Fly   436 SSNGEEPSSSIPDLEFDGTTVLCRVCGDKASGFHYGVHSCEGCKGFFRRSIQQKIQYRPCTKNQQ 500
            |...|:||||..::|       ||||||||||||||||:||||||||||:|:.|:.|..|  :..
Zfish   124 SKTPEDPSSSSLNIE-------CRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLVYDHC--DLH 179

  Fly   501 CSILRINRNRCQYCRLKKCIAVGMSRDAVRFGRVPKREKARILAAMQQSTQNRGQQ----RALAT 561
            |.|.:.:||:|||||.:||:.||||.:|:||||:|:.||.::||.......:...:    ||||.
Zfish   180 CRIHKKSRNKCQYCRFQKCLMVGMSHNAIRFGRMPQAEKEKLLAEFSSDVNHMHPESADLRALAR 244

  Fly   562 ELDDQPRLLAAVLRAHLETCEFTKEKVSAM--RQRARDCP--SYSMPTL------LACPLNP--- 613
            .|          ..::|:....||.|..|:  .:.:.:.|  .:.|.:|      :.|...|
Zfish   245 HL----------YESYLKYFPLTKAKARAILSGKTSDNAPFVIHDMKSLVEGEQMINCRYMPLHE 299

  Fly   614 ----------APELQSEQEFSQRFAHVIRGVIDFAGMIPGFQLLTQDDKFTLLKAGLFDALFVRL 668
                      ..||:....:..|.|..|..|.:||..||||..|..:|:.||||.|:.:.:.:.:
Zfish   300 HRRSDLGIMHEVELRFFHSYQSRSAEAISEVTEFAKSIPGFINLDLNDQVTLLKYGVIEVMIIMI 364

  Fly   669 ICMFDSSINSIICLNGQVMRRDAIQNGANARF--LVDSTFNFAERMNSMNLTDAEIGLFCAIVLI 731
            ..:.:.  :..:...||:.............|  :::..|.|:.:.|.:.|.|.::.||.|::::
Zfish   365 SPLMNK--DGTLISYGQIFMTREFLKSLRKPFCEMMEPKFEFSIKFNMLELDDCDMALFLAVIIL 427

  Fly   732 TPDRPGLRNLELIEKMYSRLKGCLQYIVAQNRPDQPEFLAKLLETMPDLRTLSTLHTEKLVVFRT 796
            :.|||||.|::.||.:...:...|:..:..|.||..:..||:|:.|.|||.|.|.|.:.:.:.:.
Zfish   428 SGDRPGLLNVKPIEDLQETVLHSLELQLKINHPDSLQLFAKVLQKMTDLRQLVTDHVQLIQMMKE 492

  Fly   797 EHKELLRQQMWSM 809
            ...:      ||:
Zfish   493 TEAD------WSL 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eip75B	NP_730321.1	NR_DBD_REV_ERB	453..541	CDD:143540	53/87 (61%)
		NR_LBD_REV_ERB	609..796	CDD:132738	54/201 (27%)
pparg	NP_571542.2	None