Protein Alignment Eip75B and PPARD

DIOPT Version :9

• Sequence 1: NP_001246821.1
• Gene: Eip75B / 39999
• FlyBaseID: FBgn0000568
• Length: 1412
• Species: Drosophila melanogaster
• Sequence 2: NP_001165289.1
• Gene: PPARD / 5467
• HGNCID: 9235
• Length: 441
• Species: Homo sapiens
• Alignment Length: 405
• Identity: 139/405 - (34%)
• Similarity: 210/405 - (51%)
• Gaps: 65/405 - (16%)

  Fly   426 SSSNTNNSSSSSNGEEPSSSIPDLEF--DGTT-----VLCRVCGDKASGFHYGVHSCEGCKGFFR 483
            |||.|:.|.|||    |.|.:..|:.  ||.:     :.||||||||||||||||:|||||||||
Human    39 SSSYTDLSRSSS----PPSLLDQLQMGCDGASCGSLNMECRVCGDKASGFHYGVHACEGCKGFFR 99

  Fly   484 RSIQQKIQYRPCTKNQQCSILRINRNRCQYCRLKKCIAVGMSRDAVRFGRVPKREKARILAAMQQ 548
            |:|:.|::|..|.::  |.|.:.|||:|||||.:||:|:|||.:|:||||:|:.||.:::|.:
Human   100 RTIRMKLEYEKCERS--CKIQKKNRNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGL-- 160

  Fly   549 STQNRGQQRALATELDDQPRLLAAVLRAHLETCEFTKEKV-SAMRQRARDCPSYSMP-------T 605
             |.|.|.|  ...::.|.......:..|:|:....||:|. |.:..:|    |::.|       |
Human   161 -TANEGSQ--YNPQVADLKAFSKHIYNAYLKNFNMTKKKARSILTGKA----SHTAPFVIHDIET 218

  Fly   606 L-----------LACPLNPAPELQSEQEFSQRFAHV-----------IRGVIDFAGMIPGFQLLT 648
            |           |...|.|..|:.         .||           :|.:.:||..||.|..|.
Human   219 LWQAEKGLVWKQLVNGLPPYKEIS---------VHVFYRCQCTTVETVRELTEFAKSIPSFSSLF 274

  Fly   649 QDDKFTLLKAGLFDALFVRLICMFDSSINSIICLNGQVMRRDAIQNGANARF--LVDSTFNFAER 711
            .:|:.||||.|:.:|:|..|..:.:.  :.::..||...............|  :::..|.||.:
Human   275 LNDQVTLLKYGVHEAIFAMLASIVNK--DGLLVANGSGFVTREFLRSLRKPFSDIIEPKFEFAVK 337

  Fly   712 MNSMNLTDAEIGLFCAIVLITPDRPGLRNLELIEKMYSRLKGCLQYIVAQNRPDQPEFLAKLLET 776
            .|::.|.|:::.||.|.:::..|||||.|:..:|.:...:...|::.:..|.||......|||:.
Human   338 FNALELDDSDLALFIAAIILCGDRPGLMNVPRVEAIQDTILRALEFHLQANHPDAQYLFPKLLQK 402

  Fly   777 MPDLRTLSTLHTEKL 791
            |.|||.|.|.|.:.:
Human   403 MADLRQLVTEHAQMM 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eip75B	NP_001246821.1	NR_DBD_REV_ERB	453..541	CDD:143540	55/92 (60%)
		NR_LBD_REV_ERB	609..796	CDD:132738	54/196 (28%)
PPARD	NP_001165289.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..54		9/18 (50%)
		NR_DBD_Ppar	73..156	CDD:143523	54/84 (64%)
		NR_LBD_PPAR	173..440	CDD:132730	67/260 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S6008
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm40886
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24082
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.960