Protein Alignment Eip75B and rxrgb

DIOPT Version :10

• Sequence 1: NP_730321.1
• Gene: Eip75B / 39999
• FlyBaseID: FBgn0000568
• Length: 1412
• Species: Drosophila melanogaster
• Sequence 2: XP_005160723.1
• Gene: rxrgb / 436617
• ZFINID: ZDB-GENE-040718-34
• Length: 465
• Species: Danio rerio
• Alignment Length: 598
• Identity: 163/598 - (27%)
• Similarity: 229/598 - (38%)
• Gaps: 195/598 - (32%)

  Fly   231 PLHHHSRSAPVSPVIARRGGAAAYMDQQYQQRQTPPLAPPPPPPPPPPPPPPPQQQQQQYISTGV 295
            |||..|           .||...:    |.|..:|..:.|..||
Zfish     8 PLHGQS-----------HGGENGH----YSQYSSPLNSSPSQPP--------------------- 36

  Fly   296 PPPTAAARKFVVSTSTRHVNVIASNHFQQQQQQHQAQQHQQQHQQHQQHQQHVIASVSSSSSSSA 360
                      |:|:...|.:||:|                               |....|..|.
Zfish    37 ----------VMSSMVGHPSVISS-------------------------------SRPLPSPMST 60

  Fly   361 IGS--GGSSSSHIFRTPVVSSSSSS-----NMHHQQQQQQQQSSL---GNSVMRPPPPPPPPKVK 415
            :||  .|..|.:...||.:||.|.|     :|........|.:||   ||..::|||...|
Zfish    61 LGSSMNGLPSPYSVITPSLSSPSISLPSTPSMGFNTLNSPQMNSLSMNGNEDIKPPPGLAP---- 121

  Fly   416 HASSSSSGNSSSSNTNNSSSSSNGEEPSSSIPDLEFDGTTVLCRVCGDKASGFHYGVHSCEGCKG 480
                  .||.||....:..|.|..                 :|.:|||::||.||||:|||||||
Zfish   122 ------LGNMSSYQCTSPGSLSKH-----------------ICAICGDRSSGKHYGVYSCEGCKG 163

  Fly   481 FFRRSIQQKIQYRPCTKNQQCSILRINRNRCQYCRLKKCIAVGMSRDAVRFGRVPKREKARILAA 545
            ||:|:|::.:.| .|...::|.|.:..||||||||.:||:|:||.|:||
Zfish   164 FFKRTIRKDLTY-TCRDIKECLIDKRQRNRCQYCRYQKCLAMGMKREAV---------------- 211

  Fly   546 MQQSTQNRGQQRALATEL-------DDQP--RLLAAVLRAHLETCEFTKEKVSAMRQRARDCPSY 601
              |..:.||:::: .||:       :|.|  ::|.|.|....:|..:|:..           ||.
Zfish   212 --QEERQRGKEKS-DTEVETTSRFNEDMPVDKILDAELSVEPKTETYTESS-----------PSN 262

  Fly   602 SM--PTLLACPLNPAPELQSEQEFSQRFAHVIRGVIDFAGMIPGFQLLTQDDKFTLLKAGLFDAL 664
            |.  |....|      ....:|.|:         ::::|..||.|..|..||:..||:||..:.
Zfish   263 STNDPVTNIC------HAADKQLFT---------LVEWAKRIPHFSDLPLDDQVILLRAGWNEL- 311

  Fly   665 FVRLICMFDSSINSIICLNG-------QVMRRDAIQNGANARFLVDSTFN-----FAERMNSMNL 717
               ||..|  |..||...:|       .|.|..|...|      |.|.||     ...:|..|.:
Zfish   312 ---LIASF--SHRSITVKDGILLGTGLHVHRSSAHSAG------VGSIFNRVLTELVSKMKDMQM 365

  Fly   718 TDAEIGLFCAIVLITPDRPGLRNLELIEKMYSRLKGCLQYIVAQNRPDQPEFLAKLLETMPDLRT 782
            ...|:|...||||..||..||.|...:|.:..::...|:....|..||||...||||..:|.||:
Zfish   366 DKTELGCLRAIVLFNPDAKGLSNSLEVEALREKVYASLETYTKQKYPDQPGRFAKLLLRLPALRS 430

  Fly   783 LSTLHTEKLVVFR 795
            :.....|.|..|:
Zfish   431 IGLKCLEHLFFFK 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eip75B	NP_730321.1	NR_DBD_REV_ERB	453..541	CDD:143540	41/87 (47%)
		NR_LBD_REV_ERB	609..796	CDD:132738	59/199 (30%)
rxrgb	XP_005160723.1	Nuc_recep-AF1	27..136	CDD:463363	37/180 (21%)
		NR_DBD_RXR	139..215	CDD:143514	42/111 (38%)
		NR_LBD_RXR_like	235..443	CDD:132741	69/245 (28%)