Protein Alignment Eip75B and knrl

DIOPT Version :9

• Sequence 1: NP_001246821.1
• Gene: Eip75B / 39999
• FlyBaseID: FBgn0000568
• Length: 1412
• Species: Drosophila melanogaster
• Sequence 2: NP_001303368.1
• Gene: knrl / 40285
• FlyBaseID: FBgn0001323
• Length: 647
• Species: Drosophila melanogaster
• Alignment Length: 926
• Identity: 172/926 - (18%)
• Similarity: 290/926 - (31%)
• Gaps: 337/926 - (36%)

  Fly   458 CRVCGDKASGFHYGVHSCEGCKGFFRRSIQQKIQYRPCTKNQQCSILRINRNRCQYCRLKKCIAV 522
            |:|||:.|:|||:|..:|||||.||.||.........|..|.:|.|.:.||..|:.||||||:.|
  Fly    14 CKVCGEPAAGFHFGAFTCEGCKSFFGRSYNNLSSISDCKNNGECIINKKNRTACKACRLKKCLMV 78

  Fly   523 GMSRDAVRFGRVPKREKARILAAMQQSTQNRGQQRALATELDDQPRLLAAVLRAHLETCEFTKEK 587
            |||:...|:||.....|...|                   |.:|.:...|.:.||..:
  Fly    79 GMSKSGSRYGRRSNWFKIHCL-------------------LQEQQQQAVAAMAAHHNS------- 117

  Fly   588 VSAMRQRARDCPS------YSMPT----LLACPLNPAPELQSEQEFSQRFAHVIRGVIDFAGMIP 642
                 |:|....|      ..||.    :...| .||.            |....|::...|..|
  Fly   118 -----QQAGGGSSGGSGGGQGMPNGVKGMSGVP-PPAA------------AAAALGMLGHPGGYP 164

  Fly   643 GFQLLTQDDKFTLLKAGLFDALFVRLICMFDSSINSIICLNGQVMRRDAIQNGANARFLVDSTFN 707
            |.        :.:..||                                   |::
  Fly   165 GL--------YAVANAG-----------------------------------GSS---------- 176

  Fly   708 FAERMNSMNLTDAEIGLFCAIVLITPDRPGLRNLELIEKMYSRLKGCLQYIVAQNRPDQPEFLAK 772
                                           |:.|  |.|...|.|.::|
  Fly   177 -------------------------------RSKE--ELMMLGLDGSVEY--------------- 193

  Fly   773 LLETMPDLRTLSTLHTEKLVVFRTEHKE-LLRQQMWSMEDGNNSDGQQNKSPSGSWADAMDVEAA 836
                                   ..||. ::.....|..|.:|||            .:::|.:.
  Fly   194 -----------------------GSHKHPVVASPSVSSPDSHNSD------------SSVEVSSV 223

  Fly   837 K-SPL-------GSVSSTESADLDYGSPSSSQPQGVSLPSPPQQQPSALASSAPLLAATLSGGCP 893
            : :||       .|..|:..||..:.........||:...|||.:.. |:...||         |
  Fly   224 RGNPLLHLGGKSNSGGSSSGADGSHSGGGGGGGGGVTPGRPPQMRKD-LSPFLPL---------P 278

  Fly   894 LRNRANSGSSGDSGAAEMDIVGSHAHLTQNGLTI----TPIVRHQQ------QQQQQQQIGILNN 948
            .           .|.|.|.::...|.|..:.|..    ..:..|.|      .:|||..:.....
  Fly   279 F-----------PGLASMPVMPPPAFLPPSHLLFPGYHPALYSHHQGLLKPTPEQQQAAVAAAAV 332

  Fly   949 AHSRNLNG-------GHAMCQQQQQHPQLHHHLTAGAARYRKLDSPTDSGIESGNEKNECKAVSS 1006
            .|..|.:|       |.:.....|||             :::.|.|..:...|.:..|. ..:::
  Fly   333 QHLFNSSGAGQRFAPGTSPFANHQQH-------------HKEEDQPAPARSPSTHANNN-HLLTN 383

  Fly  1007 GGSSSCSSPRSSVDDALDCSDAAANHNQVVQHPQLSVVSVSPVRSPQPSTS--SHLKRQIVEDMP 1069
            ||::                      :::.:...|..|..|..:||.|:|.  .|.|:.
  Fly   384 GGAA----------------------DELTKRFYLDAVLKSQQQSPPPTTKLPPHSKQD------ 420

  Fly  1070 VLKRVLQAPPLYDTNSLM-DEAYKPHKKFRALRHREFETAEAD-----ASSSTSGSNSLSAGSPR 1128
                       |..::|: ..:....::.::.::.|.:.|.||     |.......:.:.:.:|.
  Fly   421 -----------YSISALVTPNSESGRERVKSRQNEEDDEARADGIIDGAEHDDEEEDLVVSMTPP 474

  Fly  1129 QSPVPNSVATPPPSAASAAAGNPAQSQLHMHLTRSSPKASMASSHSVLAKSLMAEPRMTPEQMKR 1193
            .||......||.......:.|......|.|..|.||..:..:|            |.:.||....
  Fly   475 HSPAQQEERTPAGEDPRPSPGQDNPIDLSMKTTGSSLSSKSSS------------PEIEPETEIS 527

  Fly  1194 SDIIQNYLKRENSTAASSTTNGVGNRSPSSSSTPPPSAVQNQQRWGSSSVITTTCQQRQQSVSPH 1258
            ||:.:|....::.....:....:..|     .|..|...::.         ::|.:..:.|:...
  Fly   528 SDVEKNDTDDDDEDLKVTPEEEISVR-----ETADPEIEEDH---------SSTTETAKTSIENT 578

  Fly  1259 SNGSSSSSSSSSSSSSSSSSTSSNCSSSSASSCQYFQSPHSTSNGTSAPASSSSGSNSATPLLEL 1323
            .|.::|.|:::::::::::|..|:..:|.....:..:         ...|||.:|....   ||.
  Fly   579 HNNNNSISNNNNNNNNNNNSILSDSEASETIKRKLDE---------LIEASSENGKRLR---LEA 631

  Fly  1324 QVDIADSAQPLNLSKK 1339
            .|.:|.| ..|:|:.|
  Fly   632 PVKVATS-NALDLTTK 646

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eip75B	NP_001246821.1	NR_DBD_REV_ERB	453..541	CDD:143540	39/82 (48%)
		NR_LBD_REV_ERB	609..796	CDD:132738	18/186 (10%)
knrl	NP_001303368.1	NR_DBD_like	12..96	CDD:295381	38/81 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910