Protein Alignment Eip75B and nr1d2a

DIOPT Version :9

• Sequence 1: NP_001246821.1
• Gene: Eip75B / 39999
• FlyBaseID: FBgn0000568
• Length: 1412
• Species: Drosophila melanogaster
• Sequence 2: NP_001124064.2
• Gene: nr1d2a / 402815
• ZFINID: ZDB-GENE-040504-1
• Length: 504
• Species: Danio rerio
• Alignment Length: 542
• Identity: 181/542 - (33%)
• Similarity: 264/542 - (48%)
• Gaps: 133/542 - (24%)

  Fly   345 QQHVIASVSSSSSSSAIGSGGSSSSHIFRTPVVSSSSSSNMHHQQQQQQQQSSLGNSVMRPPPPP 409
            |..|||.|.||||:|:..|..|.||       .|.|.||:                       ||
Zfish     6 QGGVIAYVCSSSSASSPESCMSDSS-------ASQSPSSS-----------------------PP 40

  Fly   410 PPPKVKHASSSS---------SGNSSSSNTNNSSSSSNGEEPSSSIPDLEFDGTTVLCRVCGDKA 465
            .|.|...|:..|         .|::|..:..|.||.:            :.:|..:||:||||.|
Zfish    41 LPTKASRATDLSISAGMLKHTRGHTSDKSLANKSSIT------------KLNGMVLLCKVCGDVA 93

  Fly   466 SGFHYGVHSCEGCKGFFRRSIQQKIQYRPCTKNQQCSILRINRNRCQYCRLKKCIAVGMSRDAVR 530
            ||||||||:||||||||||||||.|||:.|.|.:.|:|:||||||||.||.|||::|||||||||
Zfish    94 SGFHYGVHACEGCKGFFRRSIQQNIQYKKCLKTESCTIVRINRNRCQQCRFKKCLSVGMSRDAVR 158

  Fly   531 FGRVPKREKARILAAMQQSTQNRGQQRALATEL---------------DDQPR------------ 568
            |||:|||||.|:|..||.:..|......|...|               .|.||
Zfish   159 FGRIPKREKQRMLLEMQTAMNNMMNNSQLQHMLHVSPSDSSSSSSASPPDSPRSSTESLVPMDTA 223

  Fly   569 ---------------LLAAVLRAHLETCEFTKEKVSAMRQRARDCPSYS-------------MPT 605
                           ..|:|..|..||....:|:......|..||.:.:             :||
Zfish   224 SSCSSDSGEEDGRFSYSASVSPAASETLSREEEEPQMQCWRRSDCQNTTGPYREQTAQQCIRLPT 288

  Fly   606 -----------------LLACPLNPAPELQSE-------QEFSQRFAHVIRGVIDFAGMIPGFQL 646
                             .|.||::.:|.:.:.       :|||:.|...:|.|::||..|||||.
Zfish   289 ENMSYCRRNMNEGGNRAHLVCPMSASPFVDASRPGHEVWEEFSRSFIPAVREVVEFAKRIPGFQE 353

  Fly   647 LTQDDKFTLLKAGLFDALFVRLICMFDSSINSIICLNGQVMRRDAIQN-GANARFLVDSTFNFAE 710
            |:|.|:..|||||.|:.|.||.:.:||....::..::|:....|.::: ||..  |::..|.|:|
Zfish   354 LSQHDQVNLLKAGTFEVLMVRFVPLFDVQQRTVSFMSGRRYSVDLLRSMGAGE--LLNCMFEFSE 416

  Fly   711 RMNSMNLTDAEIGLFCAIVLITPDRPGLRNLELIEKMYSRLKGCLQYIVAQNRPDQPEFLAKLLE 775
            ::.::.|.|.|:.||.|:||::.||..:.::..:|.:...|...|:.::.:|..::.....|||.
Zfish   417 KLAALQLNDEEMSLFSAVVLVSADRSAIEDVVGVEALQESLIRALRNLIMKNHSNESSVFTKLLL 481

  Fly   776 TMPDLRTLSTLHTEKLVVFRTE 797
            .:|:||:|:.:|:|:|:.|:.:
Zfish   482 KLPELRSLNNMHSEELLAFKIQ 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eip75B	NP_001246821.1	NR_DBD_REV_ERB	453..541	CDD:143540	67/87 (77%)
		NR_LBD_REV_ERB	609..796	CDD:132738	63/194 (32%)
nr1d2a	NP_001124064.2	NR_DBD_REV_ERB	81..169	CDD:143540	67/87 (77%)
		NR_LBD	314..502	CDD:299703	61/189 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	133	1.000	Domainoid score	I5003
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002268
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1497
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.910