Protein Alignment Eip75B and rarga

DIOPT Version :9

• Sequence 1: NP_001246821.1
• Gene: Eip75B / 39999
• FlyBaseID: FBgn0000568
• Length: 1412
• Species: Drosophila melanogaster
• Sequence 2: NP_571414.1
• Gene: rarga / 30606
• ZFINID: ZDB-GENE-980526-531
• Length: 499
• Species: Danio rerio
• Alignment Length: 589
• Identity: 151/589 - (25%)
• Similarity: 232/589 - (39%)
• Gaps: 162/589 - (27%)

  Fly   392 QQQQSSLGNSVMRPPPPPPPPKVKHASSSSSGNSSSSNTNNSSSSSNGEEPSSSIPDLEFDGTTV 456
            :.|.:|....|...|.|||||:|                         .:|
Zfish    51 ETQSTSSEEMVPSSPSPPPPPRV-------------------------YKP-------------- 76

  Fly   457 LCRVCGDKASGFHYGVHSCEGCKGFFRRSIQQKIQYRPCTKNQQCSILRINRNRCQYCRLKKCIA 521
             |.||.||:||:||||.||||||||||||||:.:.| .|.:::.|.|.::.|||||||||:||..
Zfish    77 -CFVCQDKSSGYHYGVSSCEGCKGFFRRSIQKNMVY-TCHRDKNCQINKVTRNRCQYCRLQKCFE 139

  Fly   522 VGMSRDAVRFGRVPKREKARILAAMQQSTQNRGQQRALATELDDQPRLLAAVLRAHLET----CE 582
            ||||::|||..|..|::..:......:|.:       |:.||::   |:..|.:||.||    |:
Zfish   140 VGMSKEAVRNDRNKKKKDVKDEVIPPESYE-------LSGELEE---LVNKVSKAHQETFPSLCQ 194

  Fly   583 FTKEKVSAMRQRARDCPSYSMPTLLACPLNPAPELQSEQEFSQRFAHVIRGVIDFAGMIPGFQLL 647
            ..|...::........                 :|....:||:.....|..:::||..:|||..|
Zfish   195 LGKYTTNSSSDHRIQL-----------------DLGLWDKFSELSTKCIIKIVEFAKRLPGFTTL 242

  Fly   648 TQDDKFTLLKAGLFDALFVRLICMFDSSINSIICLNGQVMRRDAIQNGANARF--LVDSTFNFAE 710
            |..|:.||||:...|.|.:|:...:....:::...:|..:.|..:.   ||.|  |.|..|.||.
Zfish   243 TIADQITLLKSACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQMH---NAGFGPLTDLVFAFAG 304

  Fly   711 RMNSMNLTDAEIGLFCAIVLITPDRPGLRNLELIEKMYSRLKGCLQYIVAQNRPDQPEFLAKLLE 775
            ::..:.:.|.|.||..||.||..||..|...|.::::...|...|:....:.||::|....::|.
Zfish   305 QLLPLEMDDTETGLLSAICLICGDRMDLEEPERVDRLQEPLLEALKIYARRRRPNKPHMFPRMLM 369

  Fly   776 TMPDLRTLSTLHTEKLVVFRTE----HKELLRQQMWSMEDGNNSDGQQNKSPSGSWADAMDVEAA 836
            .:.|||.:||...|:.:..:.|    ...|:|:.:.:.|...:......|.|.
Zfish   370 KITDLRGISTKGAERAITLKMEIPGPMPPLIREMLENPEAFEDQSEATEKKPE------------ 422

  Fly   837 KSPLGSVSSTESADLDYGSPSSSQPQGVSLPSPPQQQPSALASSAPLLAATLSGGCPLRNRANSG 901
                                          |.||...|.||                |..:....
Zfish   423 ------------------------------PEPPAPPPPAL----------------LTMKKEQE 441

  Fly   902 SSGDSGAAEMDIVGSHAHLTQNGLTITPIVRHQQQQQQQQQIGILNNAH-----------SRNLN 955
            ...||.|            |:||...:|.......:..:::.|..::..           ||..:
Zfish   442 DEDDSWA------------TENGSEPSPEEEDDDDEDGEEERGTDSDGEAWGGQEPNADVSRKSH 494

  Fly   956 GGHA 959
            ||.|
Zfish   495 GGRA 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eip75B	NP_001246821.1	NR_DBD_REV_ERB	453..541	CDD:143540	49/87 (56%)
		NR_LBD_REV_ERB	609..796	CDD:132738	53/188 (28%)
rarga	NP_571414.1	Modulating	1..76		10/49 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	51..70		6/18 (33%)
		NR_DBD_RAR	72..152	CDD:143522	49/120 (41%)
		Hinge	143..172		8/35 (23%)
		NR_LBD_RAR	176..406	CDD:132735	64/252 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	409..499		22/160 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24082
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010