Protein Alignment Eip75B and Rarg

DIOPT Version :10

• Sequence 1: NP_730321.1
• Gene: Eip75B / 39999
• FlyBaseID: FBgn0000568
• Length: 1412
• Species: Drosophila melanogaster
• Sequence 2: NP_035374.3
• Gene: Rarg / 19411
• MGIID: 97858
• Length: 458
• Species: Mus musculus
• Alignment Length: 461
• Identity: 136/461 - (29%)
• Similarity: 209/461 - (45%)
• Gaps: 85/461 - (18%)

  Fly   392 QQQQSSLGNSVMRPPPPPPPPKVKHASSSSSGNSSSSNTNNSSSSSNGEEPSSSIPDLEFDGTTV 456
            :.|.:|....|...|.|||||:|                         .:|
Mouse    64 ETQSTSSEEMVPSSPSPPPPPRV-------------------------YKP-------------- 89

  Fly   457 LCRVCGDKASGFHYGVHSCEGCKGFFRRSIQQKIQYRPCTKNQQCSILRINRNRCQYCRLKKCIA 521
             |.||.||:||:||||.||||||||||||||:.:.| .|.:::.|.|.::.|||||||||:||..
Mouse    90 -CFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVY-TCHRDKNCIINKVTRNRCQYCRLQKCFE 152

  Fly   522 VGMSRDAVRFGRVPKREKARILAAMQQSTQNRGQQRALATELDDQPRLLAAVLRAHLET----CE 582
            ||||::|||..|..|:::.:        .:.......|:.:|::   |:..|.:||.||    |:
Mouse   153 VGMSKEAVRNDRNKKKKEVK--------EEGSPDSYELSPQLEE---LITKVSKAHQETFPSLCQ 206

  Fly   583 FTKEKVSAMRQRARDCPSYSMPTLLACPLNPAPELQSEQEFSQRFAHVIRGVIDFAGMIPGFQLL 647
            ..|...::........                 :|....:||:.....|..:::||..:|||..|
Mouse   207 LGKYTTNSSADHRVQL-----------------DLGLWDKFSELATKCIIKIVEFAKRLPGFTGL 254

  Fly   648 TQDDKFTLLKAGLFDALFVRLICMFDSSINSIICLNGQVMRRDAIQNGANARF--LVDSTFNFAE 710
            :..|:.|||||...|.|.:|:...:....:::...:|..:.|..:.   ||.|  |.|..|.||.
Mouse   255 SIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQMH---NAGFGPLTDLVFAFAG 316

  Fly   711 RMNSMNLTDAEIGLFCAIVLITPDRPGLRNLELIEKMYSRLKGCLQYIVAQNRPDQPEFLAKLLE 775
            ::..:.:.|.|.||..||.||..||..|...|.::|:...|...|:....:.||.||....::|.
Mouse   317 QLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLLEALRLYARRRRPSQPYMFPRMLM 381

  Fly   776 TMPDLRTLSTLHTEKLVVFRTE----HKELLRQQMWS---MEDGNNSDGQQNKSPSGSWADAMDV 833
            .:.|||.:||...|:.:..:.|    ...|:|:.:.:   .||.::..|...|:.|...|.....
Mouse   382 KITDLRGISTKGAERAITLKMEIPGPMPPLIREMLENPEMFEDDSSKPGPHPKASSEDEAPGGQG 446

  Fly   834 EAAKSP 839
            :..:||
Mouse   447 KRGQSP 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eip75B	NP_730321.1	NR_DBD_REV_ERB	453..541	CDD:143540	49/87 (56%)
		NR_LBD_REV_ERB	609..796	CDD:132738	55/188 (29%)
Rarg	NP_035374.3	Modulating	1..89		10/49 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	58..83		6/18 (33%)
		NR_DBD_RAR	85..165	CDD:143522	49/120 (41%)
		Hinge	156..184		7/35 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	161..180		3/26 (12%)
		NR_LBD_RAR	188..418	CDD:132735	66/252 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	409..458		10/44 (23%)