Protein Alignment Eip75B and nhr-248

DIOPT Version :10

• Sequence 1: NP_730321.1
• Gene: Eip75B / 39999
• FlyBaseID: FBgn0000568
• Length: 1412
• Species: Drosophila melanogaster
• Sequence 2: NP_507334.1
• Gene: nhr-248 / 191246
• WormBaseID: WBGene00013940
• Length: 342
• Species: Caenorhabditis elegans
• Alignment Length: 376
• Identity: 84/376 - (22%)
• Similarity: 142/376 - (37%)
• Gaps: 70/376 - (18%)

  Fly   443 SSSIPDLEFDGTTVLCRVCGDKASGFHYGVHSCEGCKGFFRRSIQQKIQYRPCTKNQQCSILRIN 507
            |.|.|.:.|:.    |.|||...|...:|..:|..|..|||..:..|...| |:||.:|.|....
 Worm    12 SMSSPSVLFEA----CAVCGGPPSSRRFGALACFRCNVFFRNMLLNKRNIR-CSKNPECEIGIKT 71

  Fly   508 RNRCQYCRLKKCIAVGMSRDAVRFGRVPKREKARILAAMQQSTQNRGQQRALATELDDQPRLLAA 572
            |..||.||.|||:..||...|::     .|:|....:...:|.:.:.|    :.|:|
 Worm    72 RYACQGCRFKKCLKSGMDPKALK-----HRDKIGPRSPKMKSNKPQFQ----SAEID-------- 119

  Fly   573 VLRAHLETCEFTKEKVSAMRQRARDCPSYSMPT--LLACPLNPAPELQSEQEFSQRFAHVIRGVI 635
             .|..|:..:..|.|..          .|:.|.  .||.|        |:.....|...:  ...
 Worm   120 -FRCLLDLQKSQKSKHQ----------YYNKPNQYRLAKP--------SDINLMLRIGFM--NAT 163

  Fly   636 DFAGMIPGFQLLTQDDKFTLLK-----AGLFDALFVRLICMFDSSINSIICLNGQVMRRDAIQNG 695
            ::......|:...:..|..:|.     :||.|..|....   :::.|..:.:|...:|.||....
 Worm   164 EWGNCFRPFRYSNRSVKKRILSEFGIASGLIDQAFKTAT---ETNQNEWLFINNSCLRPDAFCTV 225

  Fly   696 ANARFLVDSTFNFAERMNSMNLTDAEIGLFCAIVLITPDRPGLRNLELIEKMYSR-----LKGCL 755
            .| .||.......::....:.|...|..:...::|:||..|....|:..:|...:     :|.||
 Worm   226 HN-DFLNTLKRELSQPFRILQLDSFECVILKTLMLLTPSFPEQSKLQSTQKSRDKCTSELMKCCL 289

  Fly   756 QYIVAQNRPDQPEFLAKLLETMPDLRTLSTL-----HTEKLVVFRTEHKEL 801
                |:......|...:::..:..:||  |:     ||::..::...|.::
 Worm   290 ----AKFPLSGVERFGEIILLIGSIRT--TVKEFHNHTKRSDLYNPNHFDI 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eip75B	NP_730321.1	NR_DBD_REV_ERB	453..541	CDD:143540	31/87 (36%)
		NR_LBD_REV_ERB	609..796	CDD:132738	36/201 (18%)
nhr-248	NP_507334.1	ZnF_C4	23..91	CDD:197701	28/68 (41%)
		HOLI	155..313	CDD:214658	31/169 (18%)