Protein Alignment Eip75B and nhr-254

DIOPT Version :10

• Sequence 1: NP_730321.1
• Gene: Eip75B / 39999
• FlyBaseID: FBgn0000568
• Length: 1412
• Species: Drosophila melanogaster
• Sequence 2: NP_503187.2
• Gene: nhr-254 / 191206
• WormBaseID: WBGene00022640
• Length: 345
• Species: Caenorhabditis elegans
• Alignment Length: 390
• Identity: 85/390 - (21%)
• Similarity: 137/390 - (35%)
• Gaps: 99/390 - (25%)

  Fly   458 CRVCGDKASGFHYGVHSCEGCKGFFRRSIQQKIQYRPCTKNQQCSILRINRNRCQYCRLKKCIAV 522
            |.||....:.|:|||.||..||.||||.|.:....:.|...:.|........:|.:||.:|||.|
 Worm     8 CAVCERFTTEFNYGVPSCNACKIFFRRLITRTAPVKQCYIGEHCFTKSPITKKCTFCRFQKCIQV 72

  Fly   523 GMSRDA-VRFGRVPKREKARILAAMQQSTQNRGQQRALATELDDQPRLLAAVLRAHLETC-EFTK 585
            ||:..: :.||.:.|                                          |.| :.|.
 Worm    73 GMTLPSYLHFGELTK------------------------------------------EKCIDSTI 95

  Fly   586 EKVSAMRQRARDC-----PSYSMPTL-LACPLNPAPELQSEQEFSQRF----AHVIRGVIDFAGM 640
            :|:..|....:|.     .||..||: ....||.....:..|.....|    .|.....:||...
 Worm    96 QKLILMEAHRKDLMANYYTSYLNPTIDEVIRLNKVEYTRKSQNHQMSFYNWAFHCCLVTVDFMKK 160

  Fly   641 IPGFQLLTQDDKFTLLKAGLFDALFVRLICMFDSSINSIICLNGQVMRRDA-------------- 691
            .....||..:|:..|:|     ..:::|..:.:|. .|:.|....:...|.
 Worm   161 FSFVNLLRFEDQKNLMK-----EFYIKLTVLINSK-QSMSCGKEGMTFPDGSDVLPPTSSEWGIS 219

  Fly   692 -----IQNGANARFLVDSTFNFAERMNSMNLTDAEIGLFCAIVLITPD-----RPGLRNLELIEK 746
                 ::|....|.:        .|::.:.:||.|..|.|.::...|:     :.|...|...:.
 Worm   220 KISQNLENKVRCRLI--------GRLSELRITDEEYLLMCVLIFCNPNLSDVSKNGKILLTSYQN 276

  Fly   747 MYSRLKGCLQYIVAQNRPDQPEFLAKLLE--TMPDLRTLSTLHTEKLVVF---RTEHKELLRQQM 806
            :||.:  .|||.:.......|...|:||.  .:..::....:|...||..   |.:.|:|:|..|
 Worm   277 LYSSV--LLQYCLLTYGKMGPSRFAELLGICQVIGIQYGDAIHYNVLVQLTKSRLDMKQLVRDGM 339

  Fly   807  806
             Worm   340  339

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eip75B	NP_730321.1	NR_DBD_REV_ERB	453..541	CDD:143540	30/83 (36%)
		NR_LBD_REV_ERB	609..796	CDD:132738	40/219 (18%)
nhr-254	NP_503187.2	ZnF_C4	7..75	CDD:197701	26/66 (39%)
		HOLI	147..308	CDD:214658	33/176 (19%)