Protein Alignment Eip75B and Ppard

DIOPT Version :9

• Sequence 1: NP_001246821.1
• Gene: Eip75B / 39999
• FlyBaseID: FBgn0000568
• Length: 1412
• Species: Drosophila melanogaster
• Sequence 2: NP_035275.1
• Gene: Ppard / 19015
• MGIID: 101884
• Length: 440
• Species: Mus musculus
• Alignment Length: 450
• Identity: 139/450 - (30%)
• Similarity: 233/450 - (51%)
• Gaps: 69/450 - (15%)

  Fly   389 QQQQQQQSSLGNSVMRPPPPPPPPKVKHASSSSSGNSSSSNTNNSSSSSNGEEPSSSIPDLEF-- 451
            :::::::.::|:..         |::......:..:||.::.:.:||      |||.:..|:.
Mouse    12 REEEKEEVAMGDGA---------PELNGGPEHTLPSSSCADLSQNSS------PSSLLDQLQMGC 61

  Fly   452 DGTT-----VLCRVCGDKASGFHYGVHSCEGCKGFFRRSIQQKIQYRPCTKNQQCSILRINRNRC 511
            ||.:     :.||||||||||||||||:||||||||||:|:.|::|..|  ::.|.|.:.|||:|
Mouse    62 DGASGGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKC--DRICKIQKKNRNKC 124

  Fly   512 QYCRLKKCIAVGMSRDAVRFGRVPKREKARILAAMQQSTQNRGQQRALATELDDQPRLLAAVLRA 576
            ||||.:||:|:|||.:|:||||:|:.||.:::|.:   |.:.|.|.  ..:|.|.......:..|
Mouse   125 QYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGL---TASEGCQH--NPQLADLKAFSKHIYNA 184

  Fly   577 HLETCEFTKEKVSAM--RQRARDCP--SYSMPTL-----------LACPLNPAPELQSEQEFSQR 626
            :|:....||:|..::  .:.:.:.|  .:.:.||           |...|.|..|:.
Mouse   185 YLKNFNMTKKKARSILTGKSSHNAPFVIHDIETLWQAEKGLVWKQLVNGLPPYNEIS-------- 241

  Fly   627 FAHV-----------IRGVIDFAGMIPGFQLLTQDDKFTLLKAGLFDALFVRLICMFDSSINSII 680
             .||           :|.:.:||..||.|..|..:|:.||||.|:.:|:|..|..:.:.  :.::
Mouse   242 -VHVFYRCQSTTVETVRELTEFAKNIPNFSSLFLNDQVTLLKYGVHEAIFAMLASIVNK--DGLL 303

  Fly   681 CLNGQVMRRDAIQNGANARF--LVDSTFNFAERMNSMNLTDAEIGLFCAIVLITPDRPGLRNLEL 743
            ..||...............|  :::..|.||.:.|::.|.|:::.||.|.:::..|||||.|:..
Mouse   304 VANGSGFVTHEFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGDRPGLMNVPQ 368

  Fly   744 IEKMYSRLKGCLQYIVAQNRPDQPEFLAKLLETMPDLRTLSTLHTEKLV-VFRTEHKELL 802
            :|.:...:...|::.:..|.||......|||:.|.|||.|.|.|.:.:. :.:||.:.||
Mouse   369 VEAIQDTILRALEFHLQVNHPDSQYLFPKLLQKMADLRQLVTEHAQMMQWLKKTESETLL 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eip75B	NP_001246821.1	NR_DBD_REV_ERB	453..541	CDD:143540	55/92 (60%)
		NR_LBD_REV_ERB	609..796	CDD:132738	54/200 (27%)
Ppard	NP_035275.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..53		8/55 (15%)
		NR_DBD_Ppar	72..155	CDD:143523	54/84 (64%)
		NR_LBD_PPAR	172..439	CDD:132730	67/267 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S6008
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm42959
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24082
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.960