Protein Alignment Eip75B and nhr-222

DIOPT Version :10

• Sequence 1: NP_730321.1
• Gene: Eip75B / 39999
• FlyBaseID: FBgn0000568
• Length: 1412
• Species: Drosophila melanogaster
• Sequence 2: NP_503990.2
• Gene: nhr-222 / 188828
• WormBaseID: WBGene00020750
• Length: 343
• Species: Caenorhabditis elegans
• Alignment Length: 374
• Identity: 85/374 - (22%)
• Similarity: 139/374 - (37%)
• Gaps: 77/374 - (20%)

  Fly   458 CRVCGDKASGFHYGVHSCEGCKGFFRRSIQQKIQYRPCTKNQQC--SILRINR-NRCQYCRLKKC 519
            |.:|...|.|.:||..||:.||.||||.|...:|:. |...::|  ......| .||:.||.:||
 Worm    12 CSICQRPAFGQNYGSFSCDACKMFFRRCIMLDLQFE-CIYQKRCFDKFTEHRRVPRCKACRFQKC 75

  Fly   520 IAVGMSRDAVRFGRVPK----REKARILAAMQQSTQNRGQQRALATELD-DQPRLLAAVLRAHLE 579
            :..||   .:|...:||    .|.|.:....|.|..|..:...|..:.. :.|:|.....|..|.
 Worm    76 LDTGM---FIRPSTLPKIESHSEHALVAILSQLSYLNARRMTVLLNKFSFENPKLQDVARRKKLT 137

  Fly   580 TCEFTKEKVSAMRQRARDCPSYSMPTLLACPLNPAPELQSEQEFSQRFAHVIRGVIDFAGMIPGF 644
            ..    ::.||......|...::|.|.:...||                      :||      .
 Worm   138 IV----DQSSAYDMSDADWRFFTMYTTIEFLLN----------------------LDF------M 170

  Fly   645 QLLTQDDKFTLLKAGLFDALFVRLICMFDSSINSIICLNGQVMR------RDAIQNGANARFLVD 703
            :.|...||..||:.  |.|....|       .||:..:.|...|      .:.:.:..:..|.|.
 Worm   171 EKLEHSDKMVLLQN--FSAKATLL-------FNSLRTVRGNNDRLTTPGGHEIVPDLMSTLFNVS 226

  Fly   704 STF------NFAERMNSMNLTDAEIGLFCAIVLITPDRPGLRN--LELIEKMYSRLKGCL----Q 756
            .:|      ....::..:.:||.|..|...|:...|...||.:  :.::..:......||    |
 Worm   227 LSFIRQIRSRVVSKLIELEITDEEFLLVTVILFCDPAISGLSSHAISILTPLRICYTSCLFQHCQ 291

  Fly   757 YIVAQNRPDQPEFLAKLL----ETMPDLRTLSTLHTEKLVVFRTEHKEL 801
            ....:|.|.:...|..|.    :.:.|:::|:.:  .|..:..:|.|:|
 Worm   292 ITCQKNFPTKFVDLLSLSHVVNKNIEDIQSLTVI--VKFYLKTSECKKL 338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eip75B	NP_730321.1	NR_DBD_REV_ERB	453..541	CDD:143540	31/89 (35%)
		NR_LBD_REV_ERB	609..796	CDD:132738	37/208 (18%)
nhr-222	NP_503990.2	ZnF_C4	12..80	CDD:197701	25/68 (37%)
		HOLI	154..314	CDD:214658	36/196 (18%)