Protein Alignment Eip75B and nhr-207

DIOPT Version :10

• Sequence 1: NP_730321.1
• Gene: Eip75B / 39999
• FlyBaseID: FBgn0000568
• Length: 1412
• Species: Drosophila melanogaster
• Sequence 2: NP_506035.1
• Gene: nhr-207 / 187661
• WormBaseID: WBGene00011098
• Length: 406
• Species: Caenorhabditis elegans
• Alignment Length: 413
• Identity: 111/413 - (26%)
• Similarity: 160/413 - (38%)
• Gaps: 121/413 - (29%)

  Fly   440 EEPSSS--IPDLEF-------DGTT--VL---CRVCGDKASGFHYGVHSCEGCKGFFRRSIQQKI 490
            ||.:|.  :||:|.       |..|  :|   ||:|.:.|.|:||.|.||.|||.||||::   |
 Worm     4 EESTSDYILPDIEITDEETKCDPNTKNILPKQCRICRNPAVGYHYDVASCNGCKAFFRRTV---I 65

  Fly   491 QYR--PCTKNQQC----SILRINRNRCQYCRLKKCIAVGMSRDAVRFGRVPKREKARILAAMQQS 549
            ..|  .|....:|    .|.:.....|..||..||..:||:..|::...:.|  |..||......
 Worm    66 TGRLPNCKFGDKCLEDHKIPKPGTRLCGSCRFSKCEQMGMNPMAIKSEIISK--KGNILKMELVK 128

  Fly   550 TQNRGQQRALATE--LDDQPRLLAAVLRA----------------HLETCEFT---KEKVSAMRQ 593
            ..|| |..|:..|  :||:...:.:.|:|                :::..:||   .||
 Worm   129 KHNR-QLIAVTKEIAIDDEFSKVLSKLKAVENKLDNLFNSRLPKNYVDYRQFTDILAEK------ 186

  Fly   594 RARDCPSYS---MPTLLACPLNPAPELQSEQEFSQ--RFAH-VIRGVIDFAGMIPGFQLLTQDDK 652
                 |:::   :|.|...|         :|.|.:  ..|| ....|::||..:..|..|   |.
 Worm   187 -----PTFAVEQIPNLSFIP---------DQVFHEYGGLAHNSFLAVVEFAKFLDFFPKL---DS 234

  Fly   653 FTLLKAGLFDALFVRLICMFDSSINSI--ICLN-------GQVMR---------RDAIQNGANA- 698
            .|.||.....||.||.:...:.||...  .|:.       |:.||         |..:|.|.:|
 Worm   235 ETQLKVVRHGALMVRGMMNTERSIRKFHSDCVRRADGSIAGKPMRNYNGIWVEQRKIVQKGLHAF 299

  Fly   699 -RFLVDSTFNFAERMNSMNLTDAEIGLFCAIVLITPDRPGL-----RNLELIEKMYSR--LKGCL 755
             |..:|.|               |..|...|||..|...||     :.||...:.|.|  |..||
 Worm   300 LRNKIDET---------------EYLLLKGIVLCNPAICGLPESAQQILEDERRRYVRSLLTYCL 349

  Fly   756 QYIVAQNRPDQPEFLAKLLETMP 778
            :....:..||:   |:.:|..||
 Worm   350 KQYGIRYGPDR---LSSILSIMP 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eip75B	NP_730321.1	NR_DBD_REV_ERB	453..541	CDD:143540	34/98 (35%)
		NR_LBD_REV_ERB	609..796	CDD:132738	52/200 (26%)
nhr-207	NP_506035.1	ZnF_C4	36..107	CDD:197701	29/73 (40%)
		HOLI	212..374	CDD:214658	49/179 (27%)