Protein Alignment Eip75B and sex-1

DIOPT Version :9

• Sequence 1: NP_001246821.1
• Gene: Eip75B / 39999
• FlyBaseID: FBgn0000568
• Length: 1412
• Species: Drosophila melanogaster
• Sequence 2: NP_001024662.1
• Gene: sex-1 / 181231
• WormBaseID: WBGene00004786
• Length: 534
• Species: Caenorhabditis elegans
• Alignment Length: 584
• Identity: 161/584 - (27%)
• Similarity: 251/584 - (42%)
• Gaps: 148/584 - (25%)

  Fly   350 ASVSSSSSSSAIGSGGSSSSHIFRTPVVSSSSSSNMHHQQQQQQQQSSLGNSVMRPPPPPPPPKV 414
            ||:.||.:|...|:.|..|........|:...||....|......||...|:...|        :
 Worm    34 ASIPSSEASKPEGTNGQWSHLPTGATYVTDEFSSEFQIQNGSTAAQSGNANNYADP--------L 90

  Fly   415 KHASSSSSGNSSSSNT-NNSSSSSNGEEPSSSI------PDLEFDGTTV----------LCRVCG 462
            .|....::.|..:.:. .:::|.::...|::|:      ||...:|.|.          .|:|||
 Worm    91 SHRRYFNNVNGYNHHQFYDTASQASVSSPATSVTSSLSPPDSLSNGHTTQRHHIGKAISFCKVCG 155

  Fly   463 DKASGFHYGVHSCEGCKGFFRRSIQQKIQYRPCTKNQQCSILRINRNRCQYCRLKKCIAVGMSRD 527
            |||||:||||.||||||||||||||:||.|| |.|.|.|.|.|.:||||||||.|||:..|||:|
 Worm   156 DKASGYHYGVTSCEGCKGFFRRSIQRKIDYR-CLKQQVCEIKRESRNRCQYCRFKKCLDSGMSKD 219

  Fly   528 AVR---FGRVPKREKARILAAMQQ-STQNRGQQRALATELDDQPRLLAAVLRAHLETCEFTKEKV 588
            :||   |....:.:|:.....:.: ||..|.:      |:|   .:..||||||.....:|..|:
 Worm   220 SVRQMKFRNAMRDDKSPDSVFVPEISTLERQE------EVD---AVYEAVLRAHTTFSFYTDIKI 275

  Fly   589 SAMRQRARDCPSYSMPTLLACPLNPAPELQSEQEFS-----QRFAHV----IRGVIDFAGMIPGF 644
            .               :::|.|.|  ..:..:.:.:     |.:||.    |:.|::|...||.|
 Worm   276 R---------------SIVARPFN--VRINEDSKMNRLNAWQIYAHEIDVDIKEVVNFVKEIPKF 323

  Fly   645 QLLTQDDKFTLLKAGLFDALFVRLICMFDSSINSIICLNGQVMRRDAIQ--NGANARFLVDSTFN 707
            ..:..:||..||:...|....:|::  ...|...::..:|:::...::|  .|:    |.|....
 Worm   324 NFINGNDKAVLLRKNAFPLYLLRIV--RGMSNRGLMLRDGRLIDFKSLQLLYGS----LADEMLA 382

  Fly   708 FAERMNSMNLTDAEIGLFCAIVLITP----------DRPGLRNLE--------LIEKMYSRLKGC 754
            ||..:.::..||.:|.||..::|..|          .:..|:.||        |.:||..|:.||
 Worm   383 FANHIITIGCTDGDIALFIVLILCQPLTTEQQFSTNFKSQLQLLEMFDFYKKVLFQKMTCRIDGC 447

  Fly   755 LQYIVAQNRPDQPEFLAKLLETMPDLRTLSTLHTEKLVVFRTEHKEL----LRQQMWSME----- 810
            ..|             .:|::.:.:|..|:.||.::|.:.|.....|    |..:|:.:.
 Worm   448 DTY-------------KQLMKCIHELNRLNELHKQQLNILRENLSFLNLPPLVVEMFQLSTLPLP 499

  Fly   811 -DGNNSDGQQNKSPSGSWADAMDVEAAKSPLGSVSSTESADLDYGSPSSSQPQGVSLPSPPQQQ 873
             :.||.:.|...:|                            ::.||   |||   .|:|.|||
 Worm   500 VNHNNQENQYTPAP----------------------------EHQSP---QPQ---QPTPNQQQ 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eip75B	NP_001246821.1	NR_DBD_REV_ERB	453..541	CDD:143540	58/100 (58%)
		NR_LBD_REV_ERB	609..796	CDD:132738	48/215 (22%)
sex-1	NP_001024662.1	NR_DBD_DmE78_like	151..231	CDD:143539	55/80 (69%)
		NR_LBD_Sex_1_like	296..488	CDD:132740	49/210 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	46	1.000	Domainoid score	I8190
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S6008
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24082
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1497
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.960