Protein Alignment Eip75B and nhr-116

DIOPT Version :10

• Sequence 1: NP_730321.1
• Gene: Eip75B / 39999
• FlyBaseID: FBgn0000568
• Length: 1412
• Species: Drosophila melanogaster
• Sequence 2: NP_507273.2
• Gene: nhr-116 / 180129
• WormBaseID: WBGene00003706
• Length: 448
• Species: Caenorhabditis elegans
• Alignment Length: 466
• Identity: 100/466 - (21%)
• Similarity: 165/466 - (35%)
• Gaps: 116/466 - (24%)

  Fly   408 PPPPPKVKHASSSSSGNSSSSNTNNSSSSSNGEEPSSSIPDLEFDGTTVLCRVCGDKASGFHYGV 472
            |...|:...:..:.|...|:|:.:..|..|..|.|:.             |.|||..|.|:||.|
 Worm    13 PVDLPEFSLSPPALSAEPSTSSPSKKSIGSRVERPTE-------------CLVCGRSAHGYHYNV 64

  Fly   473 HSCEGCKGFFRRSIQQKIQYRPCTKNQQCSIL--RINRNRCQYCRLKKCIAVGMSRDAVR----- 530
            .||.|||.||||.......: .|..::.|..|  |....:|:.|||::|::|||...|:.
 Worm    65 ASCNGCKTFFRRMCLSGRSF-SCKLDRDCFDLTKRKTPAKCRACRLQRCLSVGMDPGAMEVDEKA 128

  Fly   531 -----FGRVPKREKARILAAMQQSTQNRGQQRALATELDDQP----RLLAAVLRAHLETCEFTKE 586
                 :..:.||.|      :::..|:..|..||.:....:|    :.|...|:..::...:.:.
 Worm   129 ASSSTYKSLLKRSK------VKEEDQDDCQIIALVSNNSKKPWELVKSLENKLQNTIDMLVYLES 187

  Fly   587 KVSAMRQRA------------------------------RDCPSYSMPTLLACPLNPA------- 614
            ||...|:.:                              ::||..|....|..|.:|:
 Worm   188 KVEKFRKSSYNPDWNEMDGLEFLLKTESRIGFADRYGPMKECPIRSDQKKLPPPPHPSSAKFGGP 252

  Fly   615 ---PELQSEQEFSQRFAHVIRGVIDFAGMIPGFQLLTQDDKFTLLKAGLFDALFVRLICMFDSSI 676
               |:.:....|:      :...:::|.....|..|...|||.|.|       .:.|.||
 Worm   253 KHNPDRKQWMYFN------LFTTVEYAKTFMFFHRLDSRDKFILTK-------HITLSCM----- 299

  Fly   677 NSIICLNGQVMRRDAIQNGANARFLVDSTFNFAERMNSM------NLTDAEIGLFCAIVLITPDR 735
            |..:.......:.:.:.|.....|...:..::..:..|:      .:...|..|..||.|..|..
 Worm   300 NLHLSYISVARKSEVLTNPDGTSFPSRTQAHYTSKTMSVAPLIRYQIQYIEYTLLKAICLCNPAV 364

  Fly   736 PGLRN--LELIEKMYSRLKGCLQYIVAQNRPDQPEFLAKLLE----------TMPDLRTLSTL-- 786
            |.|.:  .|::.|...:....|.....:.|.|.|...|:|::          ...||..|..|
 Worm   365 PDLSHHAQEILSKEREKYADALFDYCLRTRNDGPSHFAQLMQIFDVLERQQKLQKDLHLLYILPT 429

  Fly   787 --HTEKLVVFR 795
              |..|.:|.|
 Worm   430 LAHAPKCLVIR 440

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eip75B	NP_730321.1	NR_DBD_REV_ERB	453..541	CDD:143540	34/99 (34%)
		NR_LBD_REV_ERB	609..796	CDD:132738	43/219 (20%)
nhr-116	NP_507273.2	ZnF_C4	50..119	CDD:197701	30/69 (43%)
		HOLI	262..414	CDD:214658	32/169 (19%)