Protein Alignment Eip75B and nhr-51

DIOPT Version :10

• Sequence 1: NP_730321.1
• Gene: Eip75B / 39999
• FlyBaseID: FBgn0000568
• Length: 1412
• Species: Drosophila melanogaster
• Sequence 2: NP_506898.2
• Gene: nhr-51 / 180052
• WormBaseID: WBGene00003641
• Length: 371
• Species: Caenorhabditis elegans
• Alignment Length: 380
• Identity: 83/380 - (21%)
• Similarity: 137/380 - (36%)
• Gaps: 113/380 - (29%)

  Fly   458 CRVCGDKASGFHYGVHSCEGCKGFFRRSIQQKIQYRPCTKNQQCSILRINRNRCQYCRLKKCIAV 522
            |.:|..||:|.||||.||..||.||.|.:.:.:.| .|.|..:|....|...:|:.||.:||:.:
 Worm     5 CLICHRKAAGQHYGVLSCFACKMFFHRMVVENLHY-CCQKFNKCYEKFIILPKCKACRYQKCLEM 68

  Fly   523 GMSRDAVRFGRVPKREKARILAAMQQSTQNRGQQRAL-ATELDDQPRLLAAVLRAHLETCEFTKE 586
            ||.       ..|:|.|     :.::|...:.|:..: .:|:|:|
 Worm    69 GMQ-------AFPRRVK-----SFEESMDLKIQRMLMNLSEMDEQ-------------------- 101

  Fly   587 KVSAMRQRARDCPSYSM--PTL---------LACPLNPAPELQSEQEFSQRFAHVIRGVIDFAGM 640
                  :..|...|||:  |:|         :.....|:.:..:..|::  |..|...:..|:
 Worm   102 ------RHWRMLNSYSIEDPSLGDVLVDSNVMKIMRKPSNQKVTAHEWA--FLDVYSRISHFS-- 156

  Fly   641 IPGFQLLTQ----DDK----FTLLKAGLFDALFVRLICMFDSSINSIICL---NGQVMRRDAIQN 694
              .|:.:..    |.|    |..|:.|:|......|....|       ||   :|:.:..||:.|
 Worm   157 --NFEFMNNISFADRKLIFSFNCLRTGVFHGSMRTLREQRD-------CLLTPSGEDVYPDAVHN 212

  Fly   695 ------------------------GANARFLVDSTFNFAERMNSMNLTD------------AEIG 723
                                    ..|..:.:.|...|.....|.||:|            ....
 Worm   213 LFKDSPGLLNRTCCLLVSKLIELKVTNEEYQLLSLIFFCNPTISHNLSDFARNTLASHQIKYSSA 277

  Fly   724 LFCAIVLITPDRPGLRNLELIEKMY--SRLKGCLQYIVAQNRPDQPEFLAKLLET 776
            ||..:.:..|....:|..|||..::  :|:...:|::....:...|.|..|.|.|
 Worm   278 LFRHLQITNPGTAPVRFQELISLVHVINRVTNDMQHVSMMFQCMIPSFKFKQLVT 332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eip75B	NP_730321.1	NR_DBD_REV_ERB	453..541	CDD:143540	31/82 (38%)
		NR_LBD_REV_ERB	609..796	CDD:132738	41/217 (19%)
nhr-51	NP_506898.2	ZnF_C4	4..70	CDD:197701	26/65 (40%)
		HOLI	144..307	CDD:214658	32/175 (18%)