Protein Alignment Eip75B and nhr-7

DIOPT Version :9

• Sequence 1: NP_001246821.1
• Gene: Eip75B / 39999
• FlyBaseID: FBgn0000568
• Length: 1412
• Species: Drosophila melanogaster
• Sequence 2: NP_502117.2
• Gene: nhr-7 / 178035
• WormBaseID: WBGene00003606
• Length: 536
• Species: Caenorhabditis elegans
• Alignment Length: 593
• Identity: 136/593 - (22%)
• Similarity: 229/593 - (38%)
• Gaps: 159/593 - (26%)

  Fly   454 TTVLCRVCGDKASGFHYGVHSCEGCKGFFRRSIQQKIQYRPCTKNQQCSILRINRNRCQYCRLKK 518
            |..:|.||||..:..||||.:|.||||||||:::.......|...:.|.:.:..||.|:|||.:|
 Worm     5 TNRICAVCGDTPAKIHYGVLACFGCKGFFRRAVKDGRNKYVCRFEKNCEVTKFERNACRYCRFRK 69

  Fly   519 CIAVGMSRDAVRFGRVPKREKAR----ILAAMQQSTQNRGQQRALATEL---DDQPRLLAAVLRA 576
            |:.|||:.|.||    |.|||::    :|      ::.:...|:|:..|   .|....|:...|.
 Worm    70 CLLVGMNPDYVR----PDREKSKKGKTVL------SKKKSVSRSLSYRLADPSDWTSFLSPSSRK 124

  Fly   577 HL-------ETC----------EFTKEKVSAMRQRAR--------DCPSYSMPTLLACPLNPAPE 616
            .|       |||          .|:.:.:.|.|..||        ||.:
 Worm   125 QLSEIGKLAETCSTSTNFDGIGNFSLKSLIADRSLARKTGDSEAMDCSN---------------- 173

  Fly   617 LQSEQEFSQRFAHVIRGVIDFAGMIPGFQLLTQDD---KFTLL-KAGLFDALFVRLICMFDSSIN 677
              |.::.:::|..:.| ::.....|..|.::.:::   ||::. |:.|.....:.|: :|:|:..
 Worm   174 --SPRQLNEQFLGIER-IVQCVDYIDRFLVMLEEEHCRKFSVEDKSALISDTMIHLL-LFESTSR 234

  Fly   678 SIICLNGQVMRRDAIQNGANARFLVDSTFNFAE-RMNSMNLTDAEIGLFCAIVLITPDRPGLRNL 741
            .:               ...|..|.|...:.|: .:.:.:||.....:|...:...|
 Worm   235 FV---------------AKGAPGLEDLKLSLAQLPICTTHLTQKIADVFETYLRKPP-------- 276

  Fly   742 ELIEKMYSRLKGCLQYIV--AQN--------------RPDQPEFLAKLLETMPDLRTLSTLHTEK 790
            .:||  ||.||.   |||  |::              |.:..|.|.|:::...:..::|..::..
 Worm   277 SIIE--YSVLKA---YIVLSAESTVLSNSLNESLSLARENLSELLFKVIKHSRNKTSISAANSLS 336

  Fly   791 LVV-FRTEHKELL-----RQQMWSMEDGNNSDGQ----------QNKSPSGSWADAMDVEAAKSP 839
            .:: |..|.:.|.     .||.:.:.|   ||.:          .|...|.......:.....:.
 Worm   337 TILHFVYESRNLASRIRQSQQPFFVRD---SDPKIPFHKILTDIINPEVSDLLLTTANCRKLSTQ 398

  Fly   840 LGSVSS--------TESADLDYGSPSSSQPQGVSLPSPPQQQPSALASSAPLLAATLSGGCPLRN 896
            :||..|        :::..|.:.||.|..|..:|.|.|||||.:.. |..|..::..:...|.::
 Worm   399 MGSSLSSVPPVPPPSDTVPLFHFSPPSLSPCQISAPPPPQQQYTDY-SQMPSTSSYPANSSPFQS 462

  Fly   897 --RANSGSSGDSGAAEMDIVGSHAHLTQNGLT-----------------ITPIVRHQQQQQQQQQ 942
              |.||.||......|| .......|..||:|                 :||:.......|...:
 Worm   463 PYRPNSLSSFPKIPLEM-TKSIEEFLRPNGMTTDEMNKPLEKNWADGFRLTPVFNKDIVSQFFPE 526

  Fly   943 IGILNNAH 950
            :..:|..|
 Worm   527 LSNINQHH 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eip75B	NP_001246821.1	NR_DBD_REV_ERB	453..541	CDD:143540	39/86 (45%)
		NR_LBD_REV_ERB	609..796	CDD:132738	36/208 (17%)
nhr-7	NP_502117.2	NR_DBD_HNF4A	9..85	CDD:143518	35/79 (44%)
		NR_LBD	188..339	CDD:299703	32/179 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24082
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010