Protein Alignment Eip75B and nhr-2

DIOPT Version :9

• Sequence 1: NP_001246821.1
• Gene: Eip75B / 39999
• FlyBaseID: FBgn0000568
• Length: 1412
• Species: Drosophila melanogaster
• Sequence 2: NP_491689.4
• Gene: nhr-2 / 172251
• WormBaseID: WBGene00003601
• Length: 472
• Species: Caenorhabditis elegans
• Alignment Length: 480
• Identity: 116/480 - (24%)
• Similarity: 178/480 - (37%)
• Gaps: 146/480 - (30%)

  Fly   320 NHFQQQQQQHQAQQHQQQHQQHQQHQQHVIASVSSSS--------------SSSAIG--SGGSSS 368
            |.:||...|:.||...:.....|...|.::...:::|              ::|.:.  |...|.
 Worm    25 NAYQQSYLQNPAQWTPEMLLCMQMQMQQMVPGTATNSTYMPPQSKNTVTPNATSPLSQISDRDSG 89

  Fly   369 SHIFRTPVVSSSSSSNMHHQQQQQQQQSSLGNSVMRPPPPPPPP----KVKHASSSSSGNSSSSN 429
            :.....|:.|.:|::..::..|.|.|.:.|..:  :|......|    .:..::.||..|.:.::
 Worm    90 NDTISPPLTSQNSATTPNYHNQPQMQLTPLQQA--KPEKEEISPYAINNILSSTQSSPDNGNEAD 152

  Fly   430 TNNSSSSSNGEEPSSSIPDLEFDGT---------TVL---------------------------- 457
            ...:||......|:||....:..||         ||:
 Worm   153 DKENSSVRRNTFPASSASTKKPRGTPYDRTNTPMTVVPQMPQFAPDFSNYNLTMNAWSEFFKKDR 217

  Fly   458 CRVCGDKASGFHYGVHSCEGCKGFFRRSIQQKIQYRPCTKNQQCSILRIN-------RNRCQYCR 515
            |.||||.::|:||||.||||||||||||:.:.|.| .|||.:.|:....|       |.|||.||
 Worm   218 CMVCGDNSTGYHYGVQSCEGCKGFFRRSVHKNIAY-VCTKGENCTFSYENCAANRGVRTRCQACR 281

  Fly   516 LKKCIAVGMSRDAVRFGRVPKREKARILAAMQQSTQNRGQQRALATELDDQPRLLAAVLRAHLET 580
            ..||:||||:||.||..:                          .|:.|.:|    :|...:.|.
 Worm   282 FAKCLAVGMNRDNVRVNK--------------------------ETDKDVKP----SVASPNFEM 316

  Fly   581 CEFTKEKVSAMRQRARDCPSYSMPTLLACPLNPAPELQSEQEFSQRFAHVIRGVIDFAGMIPGF- 644
            ....||..:|.        ..:||    |    :..|.|.       .|.|..:..|...:|..
 Worm   317 TSQVKELTAAF--------VANMP----C----STHLTSG-------THAIGAIKKFIESVPALS 358

  Fly   645 QLLTQDDK---FTLLKAGLFDALFVRLICMFDSSINSIICLNGQVMRRDAIQNGANARFLVDSTF 706
            .||.:|:|   .::.|. :...|.:|....|| .|....|.|...:.|..|:|         :.|
 Worm   359 SLLPKDEKALEMSIQKV-MSGILAIRAAFTFD-PITFYSCENPVNLLRGGIRN---------TVF 412

  Fly   707 NFAERMNSMNLTDAEIGLFCAIVLI 731
            |           |.|:.|...|.::
 Worm   413 N-----------DCEVALLSGIHIL 426

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eip75B	NP_001246821.1	NR_DBD_REV_ERB	453..541	CDD:143540	49/131 (37%)
		NR_LBD_REV_ERB	609..796	CDD:132738	28/127 (22%)
nhr-2	NP_491689.4	NR_DBD_like	218..296	CDD:143512	43/78 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24082
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.100