Protein Alignment Eip75B and pparg

DIOPT Version :10

• Sequence 1: NP_730321.1
• Gene: Eip75B / 39999
• FlyBaseID: FBgn0000568
• Length: 1412
• Species: Drosophila melanogaster
• Sequence 2: XP_031757160.1
• Gene: pparg / 100144687
• XenbaseID: XB-GENE-483136
• Length: 475
• Species: Xenopus tropicalis
• Alignment Length: 467
• Identity: 154/467 - (32%)
• Similarity: 231/467 - (49%)
• Gaps: 98/467 - (20%)

  Fly   381 SSSNMHHQQ----------------------QQQQQQSSLGNSVMRPPPPPPPPKVKHASSSSSG 423
            ||.|.|::.                      :.|:.|||:   .:.||.||
 Frog    40 SSINSHYEDILDEKTFLCRGEQSPIDYKYDLKLQECQSSI---KLEPPSPP-------------- 87

  Fly   424 NSSSSNTNNSSSSSNGEE--PSSSIPDLEFDGTTVLCRVCGDKASGFHYGVHSCEGCKGFFRRSI 486
                 ..::.:..|.|.|  |:|.|        .:.||||||||||||||||:||||||||||:|
 Frog    88 -----YFSDKTQFSKGLEDAPNSFI--------AIECRVCGDKASGFHYGVHACEGCKGFFRRTI 139

  Fly   487 QQKIQYRPCTKNQQCSILRINRNRCQYCRLKKCIAVGMSRDAVRFGRVPKREKARILAA----MQ 547
            :.|:.|..|..|  |.|.:.:||:||:||.:||::||||.:|:||||:|:.||.::||.    :.
 Frog   140 RLKLIYERCDLN--CRIHKKSRNKCQFCRFQKCLSVGMSHNAIRFGRMPQAEKEKLLAEISSDID 202

  Fly   548 QSTQNRGQQRALATELDDQPRLLAAVLRAHLETCEFTKEKVSA-MRQRARD---CPSYSMPTLL- 607
            |.......||.||..|.|          ::|::...||.|..| :..||.|   ...|.|.:|:
 Frog   203 QLNPESADQRVLAKHLYD----------SYLKSFPLTKAKARAILTGRATDKSPVVIYDMNSLMM 257

  Fly   608 -------ACPLNPAPELQSE------QEFSQRFAHVIRGVIDFAGMIPGFQLLTQDDKFTLLKAG 659
                   .|   .|||...|      |....|....:|.:.:||..||||..|..:|:.||||.|
 Frog   258 GEDQIKGQC---QAPEQNKEVAIRIFQRCQSRSVEAVREITEFAKNIPGFVSLDLNDQVTLLKYG 319

  Fly   660 LFDALFVRLICMFDSSINSIICLNGQ-VMRRDAIQNGANARF--LVDSTFNFAERMNSMNLTDAE 721
            :.:.:|..|..:.:.  :.::...|| .|.|:.::: ....|  .::..|.||.|.|.:.|.|::
 Frog   320 VHEIIFTMLASLMNK--DGVLIAEGQGFMTREFLKS-LRKPFSDFMEPKFEFAIRFNGLELDDSD 381

  Fly   722 IGLFCAIVLITPDRPGLRNLELIEKMYSRLKGCLQYIVAQNRPDQPEFLAKLLETMPDLRTLSTL 786
            :.:|.|:::::.|||||.|:..||::...|...|:..:..|.||..:..||||:.|.|||.:.|.
 Frog   382 LAIFIAVIILSGDRPGLLNVGPIEEIQGSLLQALELQLKLNHPDSAQLFAKLLQKMTDLRQVVTE 446

  Fly   787 HTEKL-VVFRTE 797
            |.:.| ::.:||
 Frog   447 HVQLLQLIKKTE 458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eip75B	NP_730321.1	NR_DBD_REV_ERB	453..541	CDD:143540	53/87 (61%)
		NR_LBD_REV_ERB	609..796	CDD:132738	61/196 (31%)
pparg	XP_031757160.1	PPARgamma_N	1..81	CDD:463633	8/43 (19%)
		NR_DBD_Ppar	110..193	CDD:143523	53/84 (63%)
		NR_LBD_PPAR	209..474	CDD:132730	80/266 (30%)