Protein Alignment CG5290 and ttc27

DIOPT Version :10

• Sequence 1: NP_649026.1
• Gene: CG5290 / 39998
• FlyBaseID: FBgn0036772
• Length: 798
• Species: Drosophila melanogaster
• Sequence 2: XP_002934504.2
• Gene: ttc27 / 100380007
• XenbaseID: XB-GENE-952006
• Length: 839
• Species: Xenopus tropicalis
• Alignment Length: 781
• Identity: 234/781 - (29%)
• Similarity: 381/781 - (48%)
• Gaps: 63/781 - (8%)

  Fly    59 PNDNPTSQLKDFLL---LIFAFVQNSFTGP--------------FDKLEEYQQIHSELELEKLDA 106
            |.|....||..|||   .:..|||:::|||              |:...|.:.:.:.:
 Frog    79 PADVQNRQLMVFLLGVSCLHLFVQSNWTGPPIISIPQDFLPSSLFEHFSEQKAVSATI------- 136

  Fly   107 LEKLKASGEELNPNVKSVELLLIAREILEGLLENHPESKVLIWWRLRLICLHQHVLDDLAASLYE 171
            |..|...||.......:...|||||.|...|.....|.::|.||.||.|.:||.:||:.:..|:.
 Frog   137 LSCLILDGESAYSLTANPIFLLIARVIFVKLRNKLTEFQMLPWWTLRCINVHQQLLDERSPELFA 201

  Fly   172 QFKSAAGHLQAHFNQFESRELQSLLL---LELANGYLQFHRSEIASQILDELCKHLQVELKVEGL 233
            ..::....:|...|.|.....|.|.:   ||.:...|.::..:.|.:.|:.......:::.:.|.
 Frog   202 IAQTCTNEIQKCKNFFLEEAAQDLSVQQCLECSYTCLYYYDYKNAKEHLNAAKDMTTLQINLTGA 266

  Fly   234 LGVRTKFQQKALPQLCLKVEHLNE---QQPLPPAVQTNETTKLPKLLLLEDDTRLERIRFVELKD 295
            ||.||:||:..:.||.|.|:...:   :|.|.||....|  .|||...|||||.|.:|:   |:|
 Frog   267 LGKRTRFQENNVAQLILDVQRKGDLFLRQGLTPAPTPIE--YLPKNQDLEDDTVLNQIK---LED 326

  Fly   296 NEVMTLPSVLQ---ALVLAKVKQLKRSTPKDRLADEQLEPYTQTLLYQEHGP--FQVRQSALLLN 355
            .|...:|.:..   |::|......:::.|..:|.:|:|..:...||.|   |  :.::.:|||:.
 Frog   327 PEQFHIPDLCAEELAVILGVCIDFQKNNPVHKLTEEELLAFNSCLLSQ---PKFWALQTTALLMR 388

  Fly   356 CLQESNQRRTVERSWKQCEECVKLLDT-SEEELSLRSRLSYGFAAHLSPKWQVQLQLVDLLRSLG 419
            ...|....|.|||:..|.:   .|.|. .::|.:...||...:.:.:...|.:|.||..||..||
 Frog   389 TKLEKGSARRVERAMMQTQ---ALADQFQQKEPNCTERLKMFYCSQMPAIWDIQRQLASLLFDLG 450

  Fly   420 MTKTALDICLRIHAWQQVIECYTSLELRHKAAEIIRQELEKKPTALLYCLLGDAIDDPSFYEQAW 484
            .|.:||.|..::..|:.|:.||..|....||.||:|||||||.|..|||||||.:.|..:|::||
 Frog   451 CTSSALQIFEKLEMWEDVVICYERLGQHGKAEEILRQELEKKETPRLYCLLGDVLKDHQYYDKAW 515

  Fly   485 LYSKKTSGKAQAYWGNHFYRSADYAQAMDHFEISLEINNLQEAILLRCGYCAIQLERWEPAVKYY 549
            ..|...|.::|...|....|:.::.|..:.||.|::||.:|..:....|...|.|:.:|.|.|.:
 Frog   516 ELSNHRSARSQRSKGLLHLRNKEFKQCAECFEKSVKINPIQLGVWFSLGCAYITLQEYEGAAKAF 580

  Fly   550 LAYTHLEPNGFESWNNLAKALIKLGDKQRAHRVLGEALKCNYSNWKVWENYMLVSVDTSHWDDAM 614
            .....|||:..|:||||:.|.|:|..|.:|.|.|.||:||||.:|::||||:|.|.|...:.:|:
 Frog   581 QRCVTLEPDNAEAWNNLSSAYIRLKQKIKAFRTLQEAIKCNYEHWQIWENYLLTSTDVGEFAEAV 645

  Fly   615 RAYQRMAELKQHYLDQEVLTRIVYGVSK--EDPAGSSA--LIKRLIKLLGQQSIQHGNEPLVWEL 675
            :||.|:.:|:..:.|.:||..:|..|.:  ||..|.|.  |..:|::|:|:.:.:..::..:|::
 Frog   646 KAYHRLMDLRDKFKDVQVLKILVRAVVEGIEDHKGESTSNLKPKLLELMGRVTSRDSSDAEIWKV 710

  Fly   676 AALVAQTPL--------KKAEKLVKSYRAYTPKHLGWETKSEHALKALDLCLEVCDLSVAAITEH 732
            .|.:.....        |..:.|:|:::..|.| .|||:......:.:...:|:..:::......
 Frog   711 YARLCGNGASEKDDENDKALQYLIKAHKCETQK-TGWESDVSSFKEIIRGAVELAHVAMKCSERK 774

  Fly   733 IQEESEVMITSQLNSARLAGTSCLNALKRAINVDVSAEQTAKVEQLEKRIEDLTKIVQERMNASR 797
            ...:..|.|   |:||||...|..:..|:......|.|....:.:..|.::::...:||..|..|
 Frog   775 SNPQEAVQI---LSSARLNLRSLSSKAKQVYTDAASGEVLPDLAEDVKTMDNIISEIQEISNQLR 836

  Fly   798 S 798
            :
 Frog   837 N 837

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5290	NP_649026.1	TPR	464..655	CDD:440225	73/194 (38%)
		TPR repeat	493..520	CDD:276809	7/26 (27%)
		TPR repeat	525..555	CDD:276809	7/29 (24%)
		TPR repeat	560..588	CDD:276809	14/27 (52%)
		TPR repeat	594..622	CDD:276809	12/27 (44%)
ttc27	XP_002934504.2	TPR repeat	437..463	CDD:276809	11/25 (44%)
		TPR	496..>651	CDD:440225	61/154 (40%)
		TPR repeat	523..551	CDD:276809	7/27 (26%)
		TPR repeat	556..586	CDD:276809	7/29 (24%)
		LapB	560..>787	CDD:442196	67/230 (29%)
		TPR repeat	591..619	CDD:276809	14/27 (52%)
		TPR repeat	625..653	CDD:276809	12/27 (44%)