DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Wdr92 and AT2G43770

DIOPT Version :9

Sequence 1:	NP_649025.1	Gene:	Wdr92 / 39997	FlyBaseID:	FBgn0036771	Length:	375	Species:	Drosophila melanogaster
Sequence 2:	NP_181905.1	Gene:	AT2G43770 / 818980	AraportID:	AT2G43770	Length:	343	Species:	Arabidopsis thaliana

Alignment Length:	355	Identity:	80/355 - (22%)
Similarity:	134/355 - (37%)	Gaps:	125/355 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 FVILGSKANGHGIMDIYELNQDKLVKVKSVEKKVAFKCGTFGAASLRNRHMAIGDFEGRLQVLDM 94
            |::|  |.:.:.|:|::..:....:...|.:|.|                 ...|.|...|:..|
plant    89 FMVL--KGHKNAILDLHWTSDGSQIVSASPDKTV-----------------RAWDVETGKQIKKM 134

  Fly    95 EQPDLPVYNVKAHNGIINTIDAIGGTQIDC----GAPEIVTGSRDGAVKVWDIRQGQAPVVDMSP 155
            .:          |:..:|:.         |    |.|.|::||.||..|:||:||..|
plant   135 AE----------HSSFVNSC---------CPTRRGPPLIISGSDDGTAKLWDMRQRGA------- 173

  Fly   156 PPQMGDGVNNSSGRRDCWAVAFGNTYNAEERIVAAGYDNGDLKIFDLRSLSVRWEATMKNGICGL 220
                   :.....:....||:|.   :|.::|...|.|| |:|::|||    :.||||
plant   174 -------IQTFPDKYQITAVSFS---DAADKIFTGGVDN-DVKVWDLR----KGEATM------- 216

  Fly   221 EFDRRDIPMNKLAVTTLEGGLLVFDMRTQHPTKGFSYVEERNAGRSVGTNGVISGPKATVWVVR- 284
                           ||||        .|....|.|...:   |..:.|||:.:  |..||.:|
plant   217 ---------------TLEG--------HQDTITGMSLSPD---GSYLLTNGMDN--KLCVWDMRP 253

  Fly   285 HLPQNRDLFLTGGGTGSIRLWQYEYPDRRVIDDS---DGNKLGVAGALNML------SAATLSSQ 340
            :.||||.:.:..|       .|:.: ::.::..|   ||.|:....:..|:      |..|:...
plant   254 YAPQNRCVKIFEG-------HQHNF-EKNLLKCSWSPDGTKVTAGSSDRMVHIWDTTSRRTIYKL 310

  Fly   341 PVH------CFDWHPDKLGLAVCGAFDQSV 364
            |.|      |. :||.:..:..|.: |:::
plant   311 PGHTGSVNECV-FHPTEPIIGSCSS-DKNI 338

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Wdr92	NP_649025.1	WD40	<2..354	CDD:225201	78/343 (23%)
		WD40	77..366	CDD:295369	72/308 (23%)
		WD40 repeat	111..165	CDD:293791	15/57 (26%)
		WD40 repeat	173..210	CDD:293791	13/36 (36%)
		WD40 repeat	217..256	CDD:293791	6/38 (16%)
		WD40 repeat	280..333	CDD:293791	14/62 (23%)
		WD40 repeat	342..366	CDD:293791	6/29 (21%)
AT2G43770	NP_181905.1	WD40	49..340	CDD:238121	80/355 (23%)
		WD40 repeat	57..94	CDD:293791	2/6 (33%)
		WD40 repeat	99..135	CDD:293791	8/52 (15%)
		WD40 repeat	142..177	CDD:293791	15/57 (26%)
		WD40 repeat	183..219	CDD:293791	18/65 (28%)
		WD40 repeat	227..265	CDD:293791	14/42 (33%)
		WD40 repeat	275..299	CDD:293791	5/23 (22%)
		WD40 repeat	317..340	CDD:293791	5/24 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910